ELECTROCHEMICAL SENSOR OF MULTIWALLED CARBON NANOTUBE ELECTRODE MODIFIED BY 1-PHENYL-3-METHYL-4-ORTHOFLUORO BENZOYL-5-PYRAZOLONE FOR SENSING DOPAMINE

Mohamad Syahrizal Ahmad

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Type :	article
ISSN :	1011-3924
Main Author :	Mohamad Syahrizal Ahmad
Title :	ELECTROCHEMICAL SENSOR OF MULTIWALLED CARBON NANOTUBE ELECTRODE MODIFIED BY 1-PHENYL-3-METHYL-4-ORTHOFLUORO BENZOYL-5-PYRAZOLONE FOR SENSING DOPAMINE

Place of Production :	Tanjung Malim
Publisher :	Fakulti Sains dan Matematik
Year of Publication :	2023
Notes :	Bulletin of the Chemical Society of Ethiopia
Corporate Name :	Universiti Pendidikan Sultan Idris
HTTP Link :	Click to view web link

Abstract : Universiti Pendidikan Sultan Idris

This work explicates a simple, rapid, and sensitive method for the electrochemical detection of dopamine (DOP) utilising 1-phenyl-3-methyl-4-orthofluorobenzoyl-5-pyrazolone (HPMoFBP)/multiwalled carbon nanotube (MWCNT) carbon paste electrode (CPE). The electrochemical behaviour of DOP was performed through cyclic voltammetry and square wave voltammetry. HPMoFBP/MWCNT showed a higher current at the lower potential for the oxidation of DOP compared to bare MWCNT. The sensor's improved electrocatalytic activity was observed to detect in a 1.0 x 10-1 M phosphate buffer saline (PBS) solution at pH 8.0. A good linear regression analysis was observed between electrical response and the concentration of DOP in the range of 1 to 1000 M. Under optimized experimental conditions, 1.0 x 10-7 M has been determined as the limit of detection (LOD). The sensor has expressed considerable sensitivity towards DOP detection without interference and is successfully used to determine DOP in dopamine hydrochloride injection. 2023 Chemical Society of Ethiopia and The Authors.

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