UPSI Digital Repository (UDRep)
Start | FAQ | About

QR Code Link :

Type :thesis
Subject :QR180 Immunology
Main Author :Zailatul Hani Mohamad Yadzir
Title :Production, characterization and cross-reactivity of local bivalve allergens (IR)
Place of Production :Tanjong Malim
Publisher :Fakulti Sains dan Matematik
Year of Publication :2017
Notes :Doctoral
Corporate Name :Universiti Pendidikan Sultan Idris
PDF Full Text :Item embargoed.

Abstract : Universiti Pendidikan Sultan Idris
This study aimed to produce allergen extracts, determine the frequency and characterize the major and cross-reactive allergens of five species of local bivalves. Allergen extracts were produced from raw and cooked bivalves. The raw bivalve extracts were used in skin prick tests (SPT) on 131 atopic patients. Protein profiles, major and cross-reactive allergens were then identified by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), immunoblotting and immunoblotting inhibition tests, respectively, using sera from bivalve-allergic patients. The major allergens were then identified by mass spectrometry analysis. Research findings indicated that SDS-PAGE of raw extracts revealed 12 to 23 protein bands between 13 to 250 kDa, while the cooked extracts have fewer protein bands. 34 (26%) of the subjects had a positive SPT to at least one bivalve species. The frequency of SPT reactivity to Anadara granosa was the highest at 18%, while Perna viridis was the lowest at 5%. Immunoblotting demonstrated that the raw extracts had more allergenic proteins than the cooked extracts. The fried and roasted bivalves had lower degree of allergenicity than the boiled bivalves. Two major allergens were identified in A. granosa (36 and 40 kDa), Paphia textile (37 and 42 kDa) and P. viridis (18 and 36 kDa), while Crassostrea belcheri and Meretrix meretrix have only one major allergen at 37 and 36 kDa, respectively. Mass spectrometry analysis identified the major allergens of 36 and 37, 40, 42 and 18 kDa as tropomyosin, arginine kinase, actin and troponin C, respectively. Inhibition tests identified variable cross-rectivity patterns among bivalve allergens, from none to almost total. As conclusions, bivalves have numerous major and cross-reactive allergens with either thermal-stable or thermal-labile characteristics, contributing to variable allergenicity of bivalves. Thus, the allergenicity of bivalves can be possibly reduced by thermal treatments. Implication of this study is that these allergens can be applied for the improvement of diagnostic and therapeutic strategies of local bivalve allergy.

References

Aalberse,  R.  C.  (2000).  Structural  biology  of  allergens.  Journal  of  Allergy  and

Clinical Immunology, 106 (2), 228-238.

 

Aalberse,  R.  C.,  Akkerdaas,  J.  &  van  Ree,  R.  (2001).  Cross-reactivity  of  IgE antibodies 

to allergens. Allergy, 56, 478-490.

 

Abbas,   A.   K.,   Lichtman,   A.   H.   &   Pillai,   S.   (2012).   Cellular   and   molecular 

immunology. Elsevier Saunders. pp. 426.

 

Abdel  Rahman,  A.  M.,  Helleur,  R.  J.,  Jeebhay,  M.  F.  &  Lopata,  A.  L.  (2012). 

Characterization  of  Seafood  Proteins  Causing  Allergic  Diseases,  in  Allergic Diseases-  

Highlights  in  the  Clinic,  Mechanisms  and  Treatment,  Celso  Pereira (Ed.),        ISBN:       

 978-953-51-0227-4,        Intech,        Available        from: 

http://www.intechopen.com/books/allergic-diseases-highlights-in-the-clinic- 

mechanisms-and-treatment/characterization-of-seafood-proteins-causing- allergic-diseases.

 

Abdel Rahman, A. M., Kamath, S. D., Lopata, A. L., Robinson, J. J. & Helleur, R. J. (2011).    

Biomolecular  characterization  of  allergenic  proteins  in  snow  crab (Chionoecetes opilio) and 

de novo sequencing of the second allergen arginine kinase  using  tandem  mass  spectrometry.  

Journal  of  Proteomics,  74  (2),  231- 241.

 

Abdel Rahman, A. M., Lopata, A. L., O'Hehir, R. E., Robinson, J. J, Banoub, J. H. & Helleur,  R.  

J.  (2010).  Characterization  and  de  novo  sequencing  of  snow  crab tropomyosin  enzymatic  

peptides  by  both  electrospray  ionization  and  matrix- assisted laser desorption ionization 

QToF tandem mass spectrometry. Journal of Mass Spectrometry, 45 (4), 372-381.

 

Abramovitch, J. B., Kamath, S., Varese, N., Zubrinich, C., Lopata, A. L., O'Hehir R. E.,  et  al.  

(2013).  IgE  reactivity  of  blue  swimmer  crab  (Portunus  pelagicus) Tropomyosin, Por p 1, and 

other allergens; cross-reactivity with black tiger prawn and effects of heating. PLoS One, 8 (6), 

e67487.

 

Aebersold, R. & Mann, M. (2003). Mass spectrometry-based proteomics. Nature, 422

(6928), 198–207.

 

Agusa, T., Kunito, T., Sudaryanto, A., Monirith, I., Kan-Atireklap, S., Iwata, H., et al. (2007).  

Exposure  assessment  for  trace  elements  from  consumption  of  marine

fish in Southeast Asia. Environmental Pollution, 145, 766-777.

 

Akagawa, M., Handoyo, T., Ishii, T., Kumazawa, S., Marita, N. & Suyama, K.

(2007). Proteomic analysis of wheat flour allergens. Journal of Agricultural and

Food Chemistry, 55 (17), 6863-6870.

 

Andre, F., Andre, C., Colin, L. & Cavagna, S. (1995). IgE in stools as indicator of

food sensitization. Allergy, 50, 328-333.

 

Arai, Y., Sano, Y., Ito, K., Iwasaki, E., Mukouyama, T. & Baba, M. (1998). Food and

food additives hypersensitivity in adult asthmatics. Skin scratch test with food

allergens and food challenges in adult asthmatics. Arerugi, 47, 658-666.

 

Asha, K. K., Anandan, R., Mathew, S. & Lakshmanan, P. T. (2014). Biochemical

profile of oyster Crassostrea madrasensis and its nutritional attributes. Egyptian

Journal of Aquatic Research, 40 (1), 35-41.

 

Asha’ari, Z. A., Yusof, S., Ismail, R. & Che Hussin, C. M. (2010). Clinical features of

allergic rhinitis and skin prick test analysis based on the ARIA classification: A

preliminary study in Malaysia. Annals Academy of Medicine Singapore, 39,

619-624.

 

Ayuso, R., Reese, G., Leong-Kee, S., Plante, M. & Lehrer S. B. (2002). Molecular

basis of arthropod cross-reactivity: IgE-binding cross-reactive epitopes of

shrimp, house dust mite and cockroach tropomyosins. International Archives of

Allergy and Immunology, 129 (1), 38-48.

 

Baldassarre, A., Dragonieri, S., Luisi, V., Musti, M. & Vimercati, L. (2016).

Occupational asthma in a fruit and vegetables vendor. La Medicina del lavoro

Journal, 107 (2), 87-91.

 

Bangping, W., Zhenxing, L., Lina, Z., Yixuan, L. & Hong, L. (2011). Identification

and characterization of a new IgE-binding protein in mackerel (Scomber

japonicus) by MALDI-TOF-MS. Journal of Ocean University of China, 10 (1),

93-98.

 

Barda, I., Kankaanpää, H., Purina, I., Balode, M., Sjövall, O. & Meriluoto, J. (2015).

Bioaccumulation of hepatotoxins – A considerable risk in the Latvian

environment. Environmental Pollution, 196, 313-320.

 

Barea, P. L., Calvo, E., Rodriguez, J. A., Rementeria, A., Calcedo, R., Sevilla, M.J., et

al. (1999). Characterization of Candida albicans antigenic determinants by twodimensional

polyacry-lamide gel electrophoresis and enhanced

chemiluminescence. FEMS Immunology and Medical Microbiology, 23, 343-54.

 

Barraclough, R. M., Walker, J., Hamilton, N., Fishwick, D. & Curran, A. D. (2006).

Sensitization to king scallop (Pectin maximus) and queen scallop (Chlamys

opercularis) proteins. Occupational Medicine (London) 56 (1), 63-66.

 

Barral, P., Suárez, C., Batanero, E., Alfonso, C., Alché, J. d. D., Rodríguez,-Garcia,

M. I., et al. (2005). An olive pollen protein with allergenic activity, Ole e 10,

defines a novel family of carbohydrate-binding modules and is potentially

implicated in pollen germination. Biochemical Journal, 390 (1), 77-84.

 

Bauermeister, K., Wangorsch, A., Garoffo, L. P., Reuter, A., Conti, A., Taylor, S. R.,

et al. (2011). Generation of a comprehensive panel of crustacean allergens from

the North Sea Shrimp Crangon crangon. Molecular Immunology, 48, 1983-

1992.

 

Begin, P. & Kari, C. N. (2013). Diagnosis of food allergy. Pediatric Annals, 42 (6),

102-109.

 

Bernstein, I. L., Li, J. T., Bernstein, D. I., Hamilton, R., Spector, S. L., Sicherer, S. et

al. (2008). Allergy diagnostic testing: an updated practice parameter. Annals of

Allergy, Asthma and Immunology, 100 (3), S1-148.

 

Beyer, K., Morrow, E., Li, X. M., Bardina, L., Bannon, G. A., Burks, A. W., et al.

(2001). Effects of cooking methods on peanut allergenicity. Journal of Allergy

and Clinical Immunology, 107 (6), 1077-1081.

 

Binder, M., Mahler, V., Hayek, B., Sperr, W. R., Scholler, M., Prozell, S., et al.

(2001). Molecular and imunological characterization of arginine kinase from the

Indianmeal moth, Plodia interpunctella, a novel cross-reactive invertebrate panallergen.

Journal of Immunology, 167, 5470-5477.

 

Bindslev-Jensen, C., Ballmer-Weber, B. K., Bengtsson, U., Blanco, C., Ebner, C.,

Hourihane, J., et al. (2004). Standardization of food challenges in patients with

immediate reactions to food – Position Paper from the European Academy of

Allergology and Clinical Immunology. Allergy, 59 (7), 690-697.

 

Bobolea, I., Barranco, P., Pastor-Vargas, C., Iraola, V. & Quirce, S. (2011). Arginine

kinase from a cellar spider (Holocnemus pluchei): a new asthma-causing

allergen. International Archives of Allergy and Immunology, 155 (2), 180-186.

 

Bohle, B. (2007). The impact of pollen-related food allergens on pollen allergy.

Allergy, 62, 3-10.

 

Bolhaar, S. T., van de Weg, W. E., van Ree, R., Gonzalez-Mancebo, E., Zuidmeer,

L., Bruijnzeel-Koomen, C. A., et al. (2005). In vivo assessment with prick-toprick

testing and double-blind, placebo-controlled food challenge of

allergenicity of apple cultivars. Journal of Allergy and Clinical Immunology,

116 (5), 1080-1086.

 

Borres, M. P., Ebisawa, M. & Eigenmann, P. A. (2011). Use of allergen components

begins a new era in pediatric allergology. Pediatric Allergy and Immunology, 22

(5), 454-461.

 

Bouman, A., Heineman, M. J. & Faas, M. M. (2005). Sex hormones and the immune

response in humans. Human Reproduction Update, 11 (4), 411–423.

 

Bousquet, J., Khaltaev, N., Cruz, A. A., Denburg, J., Fokkens, W. J., Togias, A., et al.

(2008). Allergic rhinitis and its impact on asthma (ARIA) 2008 update

(incollaboration with the World Health Organization, GA(2)LEN and

AllerGen). Allergy, 63 (8), 8-160.

 

Bozkurt, H., D'Souza, D. H. & Davidson, P. M. (2015). Thermal inactivation kinetics

of hepatitis A virus in homogenized clam meat (Mercenaria mercenaria).

Journal of Applied Microbiology, 119 (3), 834-844.

 

Breiteneder, H. & Mills, E. N. C. (2005). Plant food allergens-structural and

functional aspects of allergenicity. Biotechnology Advances, 23 (6), 395-399.

 

Cabanillas, B., Maleki, S. J., Rodríguez, J., Burbano, C., Muzquiz, M., Jiménez, M.

A., et al. (2012). Heat and pressure treatments effects on peanut allergenicity.

Food Chemistry, 132, 360-366.

 

Caffarelli, C. & Petroccione, T. (2001). False-negative food challenges in children

with suspected food allergy. Lancet, 358 (9296), 1871-1872.

 

Carnés, J., Ferrer, Á., Huertas, Á. J., Andreu, C., Larramendi, C. H. & Fernández-

Caldas, E. (2007). The use of raw or boiled crustacean extracts for the diagnosis

of seafood allergic individuals. Annals of Allergy, Asthma and Immunology, 98

(4), 349-354.

 

Carrillo, T., Castillo, R., Caminero, J., Cuevas, M., Rodríguez, J. C., Acosta, O., et al.

(1992). Squid hypersensitivity: a clinical and immunologic study. Annals of

Allergy, 68, 483-487.

 

Castillo, R., Delgado, J., Quiralte, J., Blanco, C. & Carillo, T. (1996). Food

hypersensitivity among adult patients: Epidemiological and clinical aspects.

Allergologia et Immunopathologia, 24, 93-97.

 

Caubet, J. C. & Sampson, H. A. (2012). Beyond skin testing: state of the art and new

horizons in food allergy diagnostic testing. Immunology and Allergy Clinics of

North America, 32, (1), 97-109.

 

Chapman, M. D., Pomes, A., Breiteneder, H. & Ferreira, F. (2007). Nomenclature and

structural biology of allergens. Journal of Allergy and Clinical Immunology,

119, 414-420.

 

Chatterjee, U., Mondal, G., Chakraborti, P., Patra, H. K. & Chatterjee, B. P. (2006).

Changes in the allergenicity during different preparations of pomfret, hilsa,

bhetki and mackerel fish as illustrated by enzyme-linked immunosorbent assay

and immunoblotting. International Archives of Allergy and Immunology, 141, 1-

10.

 

Chehade, M., Nowak-Wegrzyn, A., Kaufman, S. S., Fishbein, T. M., Tschernia, A. &

LeLeiko, N.S. (2004). De novo food allergy after intestinal transplantation: A

report of three cases. Journal of Pediatric Gastroenterology and Nutrition, 38,

545-547.

 

Chen, H., Mao, H., Cao, M., Cai, Q., Su, W., Zhang, Y. et al. (2013). Purification,

physicochemical and immunological characterization of arginine kinase, an

allergen of crayfish (Procambarus clarkii). Food and Chemical Toxicology, 62,

475-484.

 

Chen, L. & Phillips, R. (2005). Effects of twin-screw extrusion of peanut flour on in

vitro digestion of potentially allergenic peanut proteins. Journal of Food

Protection, 68 (8),1712-1719.

 

Chen, Y., Dales, R., Tang, M. & Krewski, D. (2002). Obesity may increase the

incidence of asthma in women but not in men: longitudinal observations from

the Canadian National Population Health Surveys. American Journal of

Epidemiology, 155 (3), 191-197.

 

Chiou, Y. H., Yuo, C. Y., Wang, L. Y. & Huang, S. P. (2003). Detection of crossreactivity

for atopic immunoglobulin E against multiple allergens. Clinical and

Diagnostic Laboratory Immunology, 10, 229-232.

 

Chirumbolo, S. (2016). Is basophil activation test (BAT) really useful for allergy

diagnosis? European Annals of Allergy and Clinical Immunology, 48 (3),107-

109.

 

Choi, J. H., Yoon, S. H., Suh, J. J., Suh, C. H., Nahm, D. H., Kim, Y. K., et al. (2003).

Measurement of specific IgE to abalone and identification of IgE-binding

components. Journal of Asthma, Allergy and Clinical Immunology, 23 (2), 349-

357.

 

Chu, K. H., Wong, S. H. & Leung, S. C. (2000). Tropomyosin is the major mollusc

allergen: reverse transcriptase polymerase chain reaction, expression and IgE

reactivity. Marine Biotechnology, 2, 499-509.

 

Cianferoni, A., Novembre, E., Mugnaini, L., Lombardi, E., Bernardini, R., Pucci, N.

et al. (2001). Clinical features of acute anaphylaxis in patients admitted to a

auniversity hospital: An 11-year retrospective review. Annals of Allergy,

Asthma and Immunology, 87, 27-32.

 

Ciardiello, M. A., Tamburrini, M., Liso, M., Crescenzo, R., Rafaiani, C. & Mari, A.

(2013). Food allergen profiling: A big challenge. Food Research International,

54, 1033-1041.

 

Cooke, R. A. & Vander Veer, A. (1916). Human sensitization. Journal of

Immunology, 1, 201-305.

 

Daul, C., Slattery, M., Reese, G. & Lehrer, S. B. (1994). Identification of the major

brown shrimp (Penaeus aztecus) as the muscle protein tropomyosin.

International Archives of Allergy and Immunology, 105, 49-55.

 

Deb, A., Mukherjee, S., Saha, B. K., Sarkar, B. S., Pal, J., Pandey, N., et al. (2014).

Profile of patients with allergic rhinitis (AR): A clinical based cross-sectional

study from Kolkata, India. Journal of Clinical and Diagnostic Research, 8 (1),

67-70.

 

Desjardins, A., Malo, J. L., L’Archeveque, J., Cartier, A., McCants, M. & Lehrer, S.

B. (1995). Occupational IgE-mediated sensitization and asthma caused by clam

and shrimp. Journal of Allergy and Clinical Immunology, 96, 608-617.

 

Department of Fisheries Malaysia (DOF) (2015). Available from: URL:

http://www.dof.gov.my [20 April 2016].

 

DeWitt, A. M., Mattsson, L., Lauer, I., Reese, G. & Lidholm, J. (2004). Recombinant

tropomyosin from Penaeus aztecus (rPen a 1) for measurement of specific

immunoglobulin IgE antibodies relevant in food allergy to crustaceans and other

invertebrates. Molecular Nutrition and Food Research, 48, 370-379.

 

Dincer, T. (2006). Differences of Turkish clam (Ruditapes decussates) and Manila

clam (R. philippinarum) according to their proximate composition and heavy

metal contents. Journal of Shellfish Research, 25 (2), 455-459.

 

Dissanayake, M., Ramchandran, L., Donkor, O. N. & Vasiljevic, T. (2013).

Denaturation of whey proteins as a function of heat, pH and protein

concentration. International Dairy Journal, 31 (2), 93-99.

 

Docena, G. H., Fernandez, R., Chirdo, F. G. & Fossati, C. A. (1996). Identification of

casein as the major allergenic and antigenic protein of cow’s milk. Allergy, 51

(6), 412-416.

 

Ebo, D. G., Hagendorens, M. M., De Knop, K. J., Verweij, M. M., Bridts, C. H., De

Clerck, L. S., et al. (2010). Component-resolved diagnosis from latex allergy by

microarray. Clinical and Experimental Allergy, 40, 348-358.

 

Ebo, D. G., Hagendorens, M. M., Bridts, C. H., De Clerck, L. S. & Stevens, W. J.

(2004). Sensitization to cross-reactive carbohydrate determinants and the

ubiquitous protein profilin: mimickers of allergy. Clinical and Experimental

Allergy, 34,137-144.

 

Ebo, D. G. & Stevens, W. J. (2001). IgE-mediated food allergy-extensive review of

the literature. Acta Clinica Belgica, 56, 234-247.

 

Egger, M., Mutschlechner, S., Wopfner, N., Gadermaier, G., Briza, P. & Ferreira, F.

(2006). Pollen-food syndromes associated with weed pollinosis: an update from

the molecular point of view. Allergy, 61, 461-476.

 

Eigenmann, P. A. & Sampson, H. A. (1998). Interpreting skin prick tests in the

evaluation of food allergy in children. Pediatric Allergy and Immunology, 9 (4),

186-191.

 

Emoto, A., Ishizaki, S. & Shiomi, K. (2009). Tropomyosins in gastropods and

bivalves: Identification as major allergens and amino acid sequence features.

Food Chemistry, 114 (2), 634-641.

 

Eriksson, J., Ekerljung, L., Lotvall, J., Pullerits, T., Wennergren, G., Ronmark, E., et

al. (2010). Growing up on a farm leads to lifelong protection against allergic

rhinitis. Allergy, 65, 1397-1403.

 

Erikson, N. E., Moller, C., Werner, S., Magnusson, J., Bengtsson, U. & Zoloubas, M.

(2004). Self-reported food hypersensitivity in Sweden, Denmark, Estonia,

Lithuania and Russia. Journal of Investigational Allergology and Clinical

Immunology, 14, 70-79.

 

Esch, R. E. (1997). Allergen source materials and quality control of allergenic

extracts. Methods in Enzymology, 13, 2-13.

 

Estlander, T., Kanerva, L., Tupasela, O., Keskinen, H. & Jolanki, R. (1993).

Immediate and delayed allergy to nickel with contact urticaria, rhinitis, asthma

and contact dermatitis. Clinical and Experimental Allergy, 23, 306-310.

 

European Food Safety Authority (EFSA) (2006). Opinion of the scientific panel on

dietetic products, nutrition and allergies on a request from the Commission

related to the evaluation of mollusks for labeling purposes. EFSA J, 327, 1-25.

 

European Directorate for the Quality of Medicines (EDQM) (2010). Monograph:

Allergen Products – Producta Allergenica 01/2010:1063, In: Council of Europe

(ed.) European Pharmacopoeia, 6, 679-680.

 

Ferrão-Filho, A. d. S. & Kozlowski-Suzuki, B. (2011). Cyanotoxins: bioaccumulation

and effects on aquatic animals. Marine Drugs, 9, 2729-2772.

 

Flinterman, A. E., Hoekstra, M. O., Meijer, Y., van Ree, R., Akkerdaas, J. H.,

Bruijnzeel-Koomen, C. A., et al. (2006). Clinical reactivity to hazelnut in

children: Association with sensitization to birch pollen or nuts? Journal of

Allergy and Clinical Immunology, 118 (5), 1186-1189.

 

Food and Agriculture Organization (FAO) (2015). Global aquaculture production

statistics database updated to 2013. Fisheries and aquaculture department.

Available from: URL: http://www.fao.org [15 August 2016].

 

Food and Agriculture Organization of the United Nations (FAO)/World Health

Organization (WHO) (2001). Evaluation of allergenicity of genetically modified

foods. In: Report of a joint FAO/WHO expert consultation of allergenicity of

foods derived from biotechnology. pp. 22-5.

 

Freeman, S. & Rosen, R. H. (1991). Urticarial contact dermatitis in food handlers.

Medical Journal of Australia, 155, 91-94.

 

Fujikawa, A., Ishimaru, N., Seto, A., Yamada, H., Aki, T., Shigeta, S., et al. (1996).

Cloning and characterization of a new allergen, Mag 3, from the house dust

mite, Dermatophagoides farinae: Cross-reactivity with high-molecular-weight

allergen. Molecular Immunology, 33 (3), 311-319.

 

Funari, E. & Testai, E. (2008). Human health risk assessment related to cyanotoxins

exposure. Critical Reviews in Toxicology, 38 (2), 97-125.

 

Galli, S. J. & Tsai, M. (2010). Mast cell in allergy and infection: versatile effector and

regulatory cells in innate and adaptive immunity. European Journal of

Immunology, 40, 1843-1851.

 

García, B. E., Martínez-Aranguren, R., Bernard Alonso, A., Gamboa, P., Feo Brito,

F., Bartra, J., et al. (2016). Is the ISAC 112 microarray useful in the diagnosis of

pollinosis in Spain? Journal of Investigational Allergology and Clinical

Immunology, 26 (2), 92-99.

 

García, B. E. & Lisazo, M. T. (2011). Cross-reactivity syndromes in food allergy.

Journal of Investigational Allergology and Clinical Immunology, 21 (3), 162-

170.

 

Garcia-Orozco, K. D., Aispuro-Hernandez, E., Yepiz-Plascencia, G., Calderon-de-la-

Barca, A. M. & Sotelo-Mundo, R. R. (2007). Molecular characterization of

arginine kinase, an allergen from shrimp Litopenaeus vannamei. International

Archives of Allergy and Immunology, 144, 23-28.

 

Gautam, P., Sundaram, C. S., Madan, T., Gade, W. N., Shah, A., Sirdeshmukh, R., et

al. (2007). Identification of novel allergens of Aspergillus fumigatus using

immunoproteomics approach. Clinical and Experimental Allergy, 37 (8), 1239-

1249.

 

Gendeh, B. S., Mujahid, S. H., Murad, S. & Rizal, M. (2004). Atopic sensitization of

children with rhinitis in Malaysia. Medical Journal of Malaysia, 59 (4), 522-

529.

 

Gendeh, B. S., Murad, S., Razi, A. M., Abdullah, N., Mohamed, A. S. & Kadir, K. A.

(2000). Skin prick test reactivity to foods in adult Malaysians with rhinitis.

Otolaryngology Head Neck Surgery, 122, 758-762.

 

Gernez, Y., Waters, J., Tirouvanziam, R., Herzenberg, L. & Moss, R. (2016).

Basophil activation test determination of CD63 combined with CD203c is not

superior to CD203c alone in identifying allergic bronchopulmonary aspergillosis

in cystic fibrosis. Journal of Allergy and Clinical Immunology, pii: S0091-

6749(16)30098-7. doi: 10.1016/j.jaci.2016.04.002.

 

George, C. & Gopakumar, K. (1995). Biochemical and microbiological studies on

clam Villorita cyprinoides. Journal of the Marine Biological Association of

India, 37 (1&2), 27-30.

 

Giavi, S., Vissers, Y. M., Muraro, A., Lauener, R., Konstantinopoulos, A. P.,

Mercenier, A., et al. (2016). Oral immunotherapy with low allergenic

hydrolysed egg in egg allergic children. Allergy, doi: 10.1111/all.12905.

 

Gill, B. V., Rice, T. R., Cartier, A., Gautrin, D., Neis, B., Horth-Susin, L., et al.

(2009). Identification of crab proteins that elicit IgE reactivity in snow crabprocessing

workers. Journal of Allergy and Clinical Immunology, 124, 1055-

1061.

 

Glass, W. I., Power, P., Burt, R., Fishwick, D., Bradshaw, L. M. & Pearce, N. E.

(1998). Work-related respiratory symptoms and lung function in New Zealand

mussel openers. American Journal of Industrial Medicine, 34, 163-168.

 

Gobin, J., Agard, J., Madera, J. & Mohammed, A. (2013). The Asian Green Mussel

Perna viridis (Linnaeus 1758): 20 Years after Its Introduction in Trinidad and

Tobago. Open Journal of Marine Science, 3, 62-65.

 

Goetz, D. W. & Whisman, B. A. (2000). Occupational asthma in a seafood restaurant

worker: Cross-reactivity of shrimp and scallops. Annals of Allergy, Asthma and

Immunology, 85, 461.

 

González Galán, I., García Menaya, J. M., Jiménez Ferrera, G. & González Mateos,

G. (2002). Anaphylactic shock to oysters and white fish with generalized

urticaria to prawns and white fish. Allergologia et Immunopathologia, 30, 300-

303.

 

González-Fernández, J., Rodero, M., Daschner, A. & Cuéllar, C. (2014). New insights

into the allergenicity of tropomyosin: a bioinformatics approach. Molecular

Biology Reports, 41, 6509-6517.

 

Goodman, R. E., Silvanovich, A., Hileman, R. E., Bannon, G. A., Rice, E. A. &

Astwood, J. D. (2002). Bioinformatic methods for identifying known or

potential allergens in the safety assessment of genetically modified crops.

Comments on Toxicology, 8, 251-269.

 

G?rg, A., Weiss, W. & Dunn, M. J. (2004). Current two-dimensional electrophoresis

technology for proteomics. Proteomics, 4 (12), 3665-3685.

 

Gould, H. J. & Sutton, B. J. (2008). IgE in allergy and asthma today. Nature Reviews

Immunology, 8, 205-217.

 

Haeggstr?m, A., ?stberg, B., Stjerna, P., Graf, P. & Hallén, H. (2000). Nasal mucosal

swelling and reactivity during a menstrual cycle. ORL Journal for Oto-Rhino-

Laryngology and Its Related Specialties, 62 (1), 39–42.

 

Hajeb, P., Jinap, S., Ismail, A., Fatimah, A.B., Jamilah, B. & Abdul Rahim, M.

(2009). Assessment of mercury level in commonly consumed marine fishes in

Malaysia. Food Control, 20, 79-84.

 

Hales, B. J., Laing, I. A., Pearce, L. J., Hazell, L. A., Mills, K. L.,Chua, K. Y., et al.

(2007). Distinctive immunoglobulin E anti-house dust allergen-binding

specificities in a tropical Australian Aboriginal community. Clinical

Experimental of Allergy, 37 (9), 1357-1363.

 

Hamilton, R. G. & Franklin, A. N. (2004). In vitro assays for the diagnosis of IgEmediated

disorders. Journal of Allergy and Clinical Immunology, 114 (2), 213-

225.

 

Hamli, H., Idris, M. H., Kamal, A. B. M. & Wong, S. K. (2012). Diversity of edible

mollusc (Gastropoda and Bivalvia) at selected divison of Sarawak, Malaysia.

International Journal on Advanced Science, Engineering and Information

Technology, 2, 5-7.

 

Hawkins, A. J. S., Smith, R. F. M., Tan, S. H. & Yasin, S. B. (1998). Suspensionfeeding

behaviour in tropical bivalve mollusc: Perna viridis, Crassostrea

belcheri, Crassostrea iradelei, Saccostrea cucculata and Pinctada margarifera.

Marine Ecology Progress Series, 166, 173-185.

 

Hedlund, U., Rönmark, E., Eriksson, K., Lundbäck, B. & Järvholm, B. (2008).

Occupational exposure to dust, gases and fumes, a family history of asthma and

impaired respiratory health. Scandinavian Journal of Work, Environment and

Health, 34, 381-386.

 

Hersoug, L-G. & Linneberg, A. (2007). The link between the epidemics of obesity

and allergic diseases: does obesity induce decreased immune tolerance? Allergy,

62 (10), 1205-1213.

 

Hilger, C., Kohnen, M., Grigioni, F., Lehners, C. & Hentges, F. (1997). Allergic

cross-reactions between cat and pig serum albumin. Study at the protein and

DNA levels. Allergy, 52, 179-187.

 

Hilmenyuk, T., Bellinghausen, I., Heydenreich, B., Ilchmann, A., Toda, M., Grabbe,

S., et al. (2010). Effects of glycation of the model food allergen ovalbumin on

antigen uptake and presentation by human dendritic cells. Immunology, 129,

437-445.

 

Hindley, J., Wunschmann, S., Satinover, S. M., Woodfolk, J. A., Chew, F. T.,

Chapman, M. D., et al. (2006). Bla g 6: A troponin C allergen from Blattella

germanica with IgE binding calcium dependence. Journal of Allergy and

Clinical Immunology, 117 (6), 1389-1395.

 

Holgate, S., Bousquet, J., Wenzel, S., Fox, H., Liu, J. & Castellsague, J. (2001).

Efficacy of omalizumab, an anti-immunoglobulin E antibody, in patients with

allergic asthma at high risk of serious asthma-related morbidity and mortality.

Current Medical Research and Opinion, 17 (4), 233-240.

 

Huang, S-L., Shiao, G-M. & Chou, P. (1999). Association between body mass index

and allergy in teenage girls in Taiwan. Clinical and Experimental Allergy, 29

(3), 323-329.

 

Huber, M. (2010). Compendium of Bivalves. A full-color guide to 3,300 of the

world’s marine bivalve. A status on bivalvia after 250 years of research. Conch

books. p. 23. ISBN 978-3-939767-28-2.

 

Hussein, A. & Khaled, A. (2014). Determination of metals in tuna species and

bivalves from Alexandria, Egypt. Egyptian Journal of Aquatic Research, 40, 9-

17.

 

Ibekwe, P. U. & Ibekwe, T. S. (2016). Skin prick test analysis in allergic rhinitis

patients: A preliminary study in Abuja, Nigeria. Journal of Allergy, Article ID

3219104, 5 pages, doi:10.1155/2016/3219104.

 

Ilano, A. S., Sotto, F. B. & Juario, J. V. (2007). Sexual maturity and reproductive

cycle of Paphia textilis (Gmelin, 1791) (Bivalvia: Veneroidea) off Sillon waters,

Bantayan Island, Cebu, Philippines. Journal of Aquatic Science, 4, 89-103.

 

Ishikawa, M., Ishida, M., Shimakura, K., Nagashima, Y. & Shiomi, K. (1998).

Tropomyosin, the major oyster Crassostrea gigas allergen and its IgE-binding

epitopes. Journal of Food Science, 63 (1), 44-47.

 

Ismail, A., Badri, M. A. & Ramlan, M. N. (1993). The background levels of heavy

metal concentration in sediments of the west coast of Peninsular Malaysia.

Science of The Total Environment, 314, 315-323.

 

Jeebhay, M. F., Robins, T. G., Lehrer, S. B. & Lopata, A. L. (2001). Occupational

seafood allergy: a review. Occupational and Environmental Medicine, 58, 553-

562.

 

Jenkins, J. A., Griffiths-Jones, S., Shewry, P. R., Breiteneder, H. & Mills, C. (2005).

Structural relatedness of plant food allergens with specific reference to crossreactive

allergens: An in silico analysis. Journal of Allergy and Clinical

Immunology, 115 (1), 163-170.

 

Jeong, K. Y., Kim, C. R., Un, S., Yi, M. H., Lee, I. Y., Park, J. W., et al. (2010).

Allergenicity of recombinant troponin C from Tyrophagus putrescentiae.

International Archives of Allergy and Immunology, 151 (3), 207-213.

 

Jimenez, M., Pineda, F., Sanchez, I., Orozco, I. & Senent, C. (2005). Allergy due to

Enis macha. Allergy, 60, 1090-1091.

 

Jonasson, S. Eriksson, J., Berntzon, L., Spácil, Z., Ilag, L., Ronnevi, L. O., et al.

(2010). Transfero of a cyanobacterial neurotoxin within a temperate aquatic

ecosystem suggests pathways for human exposure. Proceedings of the National

Academy of Sciences of the United States, 17 (20), 9252-9257.

 

Kabsch, W. & Vandekerckhove, J. (1992). Structure and function of actin. Annual

Review of Biophysics and Biomolecular Structure, 21, 49-76.

 

Kalogeromitros, D., Katsarou, A., Armenaka, M., Rigopoulos, D., Zapanti, M. &

Stratigos, I. (1995). Influence of the menstrual cycle on skin-prick test reactions

to histamine, morphine and allergen. Clinical and Experimental Allergy, 25 (5),

461–466.

 

Kalyanasundaram, A. & Santiago, T. C. (2015). Identification and characterization of

new allergen troponin C (Pen m 6.0101) from Indian black tiger shrimp

Penaeus monodon. European Food Research and Technology, 240 (3), 509-

515.

 

Kamaruzzaman, B. Y., Mohd Zahir, M. S., Akbar John, B., Jalal, K. C. A.,

Shahbudin, S., Al-Barwani, S. M., et al. (2011). Bioaccumulation of some

heavy metal by green mussel Perna viridis (Linnaues 1758) from Pekan,

Pahang, Malaysia. International Journal of Biological Chemistry, 5 (1), 54-60.

 

Kamath, S. D., Abdel Rahman, A. M., Komoda, T. & Lopata, A. L. (2013). Impact of

heat processing on the detection of the major shellfish allergen tropomyosin in

crustaceans and molluscs using specific monoclonal antibodies. Food

Chemistry, 141, 4031-4039.

 

Kelly, C. & Gangur, V. (2009). Sex disparity in food allergy: evidence from the

PubMed Database. Journal of Allergy, Article ID 159845, 7 pages,

doi:10.1155/2009/159845.

 

Key, T. J., Appleby, P. N., Reeves, G. K., Roddam, A., Dorgan, J. F., Longcape, C., et

al. (2003). Body mass index, serum sex hormones, and breast cancer risk in

postmenopausal women. Journal of the National Cancer Institute, 95 (16),

1218-1226.

 

Kidon, M. I., Chiang, W. C., Liew, W. K., Ong, T. C., Tiong, Y. S., Wong, K. N., et

al. (2011). Mite component-specific IgE repertoire and phenotypes of allergic

disease in childhood: the tropical perspective. Pediatric Allergy and

Immunology, 22 (2), 202-210.

 

King, T. P., Hoffman, D., LØwenstein, H., Marsh, D. G., Platts-Mills, T. A. E. &

Thomas, W. (1995). Allergen nomenclature. Allergy, 50, 765-774.

 

Kinter, M. & Sherman, N. (2000). Protein sequencing and identification using tandem

mass spectrometry, Libre Digital.

 

Kirmaz, C., Yuksel, H., Mete, N., Bayrak, P. & Baytur, Y. B. (2004). Is the menstrual

cycle affecting the skin prick test reactivity? Asian Pacific Journal of Allergy

and Immunology, 22 (4), 197-203.

 

Kong, M., Hang, X., Wang, L., Yin, H. & Zhang, Y. (2016). Accumulation and risk

assessment of heavy metals in sediments and zoobenthos (Bellamya aeruginosa

and Corbicula fluminea) from Lake Taihu. Water Science & Technology, 73 (1),

203-214.

 

Kraneveld, A. D., Sagar, S., Garssen, J. & Folkerts, G. (2012). The two faces of mast

cells in food allergy and allergic asthma: the possible concept of Yin Yang.

Biochimica et Biophysica Acta-Molecular Basis of Disease, 1822, 93-99.

 

Kukreja, N., Singh, B. P., Arora, N., Gaur, S. N. & Sridhara, S. (2008). Identification

of Epicoccum purpurascens allergen by two-dimensional immunoblotting and

mass spectrometry. Immunobiology, 213, 67-73.

 

Kurien, B. T. & Scofield, R. H. (2006). Western blotting. Methods, 38 (4), 283-293.

Lám, H. T., Ván Tuong, N., Ekerljung L., Rönmark, E. & Lundbäck, B. (2011).

Allergic rhinitis in northern vietnam: increased risk of urban living according to

a large population survey. Clinical and Translational Allergy, 1, 7.

 

Lauer, I., Foetisch, K., Kolarich, D., Ballmer-Weber, B. K., Canti, A., Altmann, F., et

al. (2004). Hazelnut (Corylus avellana) vicilin Cor a 11: molecular

characterization of a glycoprotein and its allergenic activity. Biochemical

Journal, 383, 327-334.

 

Laxmilatha, P. (2009). Proximate composition of the surf clam Mactraviolacea

(Gmelin 1791). Indian Journal of Fisheries, 56 (2), 147-150.

 

Leao, J. D. C., Giordano, S. B. & Yunes, J. S. (2010). Microcystins uptake by the

yellow clam Mesodesma mactroides (Bivalvia, Mactroidea). Atlantica, Rio

Grande, 32 (1), 79-85.

 

Lee, R., Lovatelli, A. & Ababouch, L. (2008). Bivalve depuration: fundamental and

practical aspects. FAO Fisheries Technical Paper. No. 511, Rome, FAO.

 

Lehrer, S. B. & McCants, M. L. (1987). Reactivity of IgE antibodies with crustacea

and oyster allergens. Evidence for common antigenic structure. Journal of

Allergy and Clinical Immunology, 80, 133.

 

Le Renard, J., Sabelli, B., Taviani, M. (1996). On Candinia (Sacoglossa: Juliidae), a

new fossil genus of bivalved gastropods. Journal of Paleontology, 70 (2), 230-

235.

 

Leszczynska, J., Lacka, A., Szemraj, J., Lukamowicz, J. & Zegota, H. (2003). The

effect of microwave treatment on the immunoreactivity of gliadin and wheat

flour. European Food Research and Technology, 217 (5), 387-391.

 

Leung, N. Y., Wai, C. Y., Shu, S., Wang, J., Kenny, T. P., Chu, K. H., et al. (2014).

Current immunological and molecular biological perspectives on seafood

allergy: a comprehensive review. Clinical Reviews in Allergy & Immunology, 46

(3), 180-197.

 

Leung, P. S., Chow, W. K., Duffey, S., Kwan, H. S., Gershwin, M. E. & Chu, K. H.

(1996). IgE reactivity against a cross-reactive allergen in Crustacea and

Mollusca: Evidence for tropomyosin as the common allergen. Journal of Allergy

and Clinical Immunology, 98 (5 Pt 1), 954-961.

 

Leung, P. S. & Chu, K. H. (2001). cDNA cloning and molecular identification of the

major oyster allergen from the Pacific oyster Crassostrea gigas. Clinical and

Experimental Allergy, 31 (8), 1287-1294.

 

Li, G., Li, J. & Li, D. (2010). Seasonal variation in nutrient composition of Mytilus

coruscus from China. Journal of Agricultural and Food Chemistry, 58, 7831-

7837.

 

Liu, G. M., Cheng, H., Nesbit, J. B., Su, W. J., Cao, M. J. & Maleki, S. J. (2010).

Effects of boiling on the IgE-binding properties of tropomyosin of shrimp

(Litopenaeus vannamei). Journal of Food Scince, 75 (1), T1-T5.

 

Lopata, A. L. & Kamath, S. (2012). Shellfish allergy diagnosis- gaps and needs.

Current Allergy and Clinical Immunology, 25 (2), 60-66.

 

Luengo, O. & Cardona, V. (2014). Component resolved diagnosis: when should it be

used? Clinical and Translational Allergy, 4, 28.

 

Ma, H., Xu, W., Mai, K., Liufu, Z. & Chen, H. (2004). Cloning and characterization

of an abalone (Haliotis discus hannai) actin gene. Journal of Ocean University

of China, 3 (2), 145-149.

 

Maleki, S. J., Chung, S. Y., Champagne, E. T. & Raufman, J. P. (2010). The effects of

roasting on the allergenic properties of peanut proteins. Journal of Allergy and

Clinical Immunology, 106 (4), 763-768.

 

Mao, H. Y., Cao, M. J., Maleki, S. J., Cai, Q. F., Su, W. J., Yang, Y., et al. (2013).

Structural characterization and IgE epitope analysis of arginine kinase from

Scylla paramamosain. Molecular immunology, 56 (4), 463-470.

 

Mari, A. (2008). When does a protein become an allergen? Searching for a dynamic

definition based on most advanced technology tools. Clinical and Experimental

Allergy, 38 (7), 1089-1094.

 

Marinho, S., Morais-Almeida, M., Gaspar, A., Santa-Marta, C., Pires, G., Postigo, I.,

et al. (2006). Barnacle allergy: allergen characterization and cross-reactivity

with mites. Journal of Investigational Allergology and Clinical Immunology, 16,

117-122.

 

Marvin, L. F., Roberts, M. A. & Fay L. B. (2003). Matrix-assisted laser

desorption/ionization time-of-flight mass spectrometry in clinical chemistry.

Clinica Chimica Acta, 337, 11-21.

 

Matricardi, P. M., Kleine-Tebbe, J., Hoffmann, H. J., Valenta, R., Hilger, C.,

Hofmaier, S., et al. (2016). EAACI molecular allergology user’s guide.

Pediatric Allergy and Immunology, 27 (suppl 23), 1-250.

 

McGuire, M. & Stevely, J. (2015). Invasive Species of Florida's Coastal Waters: The

Asian Green Mussel (Perna viridis). Available from: URL:

http://edis.ifas.ufl.edu/sg094 [7 April 2016].

 

Meno, K. H. (2011). Allergen structures and epitopes. Allergy, 66 (95), 19-21.

 

Michael, R. N. & Linda, C. (2012). Allergen immunotherapy extract preparation

manual. In AAAAI Practice Management Resource Guide, 2012 ed American

Academy of Allergy, Asthma and Immunology, 1-39.

 

Mikita, C. P. & Padlan, E. A. (2007). Why is there a greater incidence of allergy to

the tropomyosin of certain animals than to that of others? Medical Hypotheses,

69, 1070-1073.

 

Mills, E. N. & Mackie, A. R. (2008). The impact of processing on allergenicity of

food. Current Opinion in Allergy and Clinical Immunology, 8 (3), 249-253.

 

Misnan, R., Murad, S., Yadzir, Z. H. M. & Abdullah, N. (2012). Identification of the

major allergens of Charybdis feriatus (red crab) and its cross-reactivity with

Portunus pelagicus (blue crab). Asian Pacific Journal of Allergy and

Immunology, 30, 285-293.

 

Misnan, R., Murad, S., Arip, M., Abdullah, N. & Mohamed, J. (2005).

Characterization of immunoglobulin E-binding proteins (IgE) of

Scomberomorus commerson Lacepede. Jurnal Sains Kesihatan Malaysia, 3 (2),

79-87.

 

Mok, W. J., Senoo, S., Itoh, T., Tsukamasa Y., Kawasaki, K. & Ando, M. (2012).

Assessment of concentrations of toxic elements in aquaculture food products in

Malaysia. Food Chemistry, 133, 1326-1332.

 

Mondoulet, L., Paty, E., Drumare, M. F., Ah-Leung, S., Scheinmann, P., Willemot, R.

M., et al. (2005). Influence of thermal processing on the allergenicity of peanut

proteins. Journal of Agricultural and Food Chemistry, 53 (11), 4547-4553.

 

Moneret-Vautrin, D. A., Kanny, G., Morisset, M., Rance, F., Fardeau, M. F. &

Beaudouin, E. (2004). Severe food anaphylaxis: 107 cases registered in 2002 by

the Allergy Vigilance Network. Allergie Immunology, 36, 46-51.

 

Morton, B. (2008). The evolution of eyes in the Bivalvia: new insights. American

Malacological Bulletin, 26 (1-2), 35-45.

 

Motoyama, K., Suma, Y., Ishizaki, S., Nagashima, Y., Lu, Y., Ushio, H., et al.

(2008). Identification of tropomyosins as major allergens in antarctic krill and

mantis shrimp and their amino acid sequence characteristics. Marine

Biotechnology (New York), 10 (6), 709-718.

 

Motoyama, K., Suma, Y., Ishizaki, S., Nagashima, Y. & Shiomi, K. (2007).

Molecular cloning of tropomyosin identified as allergens in six species of

crustaceans. Journal of Agricultural and Food Chemistry, 55 (3), 985-991.

 

Mykles, D. L., Cotton, J. L. S., Taniguchi, H., Sano, K. & Maeda, Y. (1998). Cloning

of tropomyosins from lobster (Homarus americanus) striated muscles: fast and

slow isoforms may be generated from the transcript. Journal of Muscle

Research and Cell Motility, 19, 105-115.

 

Naguit, M. R. A., Aquin, J., Tabiliran, F. P. & Raymundo, L. J. (2004). Lead and Zinc

concentrations in the Venus clam, Paphia textile (Gmelin) in soft-bottom

communities of Katipunan and Roxas, Zamboanga Del Norte: An indicator of

heavy metal contamination. Silliman Journal, 45, 96-110.

 

Nakashima, T. (1969). Studies on bronchial asthma observed in cultured oyster

workers. Hiroshima Journal of Medical Sciences, 18, 141-184.

 

Nettis, E., Pannofino, A., Dambra, P., Loria, M. P., DiMaggio, G., Damiani, E., et al.

(2001). IgE-mediated urticaria/angioedema after ingestion of mussels. Acta

Dermato-Venereologica, 81, 62.

 

Novembre, E., Cianferoni, A., Bernardini, R., Mugnaini, L., Caffarelli, C. & Cavagni,

G., et al. (1998). Anaphylaxis in children: clinical and allergologic features.

Pediatric, e1-e8.

 

Nowak-Wegrzyn, A. & Fiocchi, A. (2009). Rare, medium, or well done? The effect of

heating and food matrix on food protein allergenicity. Current Opinion in

Allergy and Clinical Immunology, 9, 234-237.

 

Nurnadia, A. A., Azrina, A. & Amin, I. (2011). Proximate composition and energetic

value of selected marine fish and shellfish from the West coast of Peninsular

Malaysia. International Food Research Journal, 18, 137-148.

 

Oliveira, T. C., Lima, S. L. & Bressan, J. (2013). Influences of different thermal

processings in milk, bovine meat and frog protein structure. Nutricion

Hospitalaria, 28 (3), 896-902.

 

Ortea, I., Canas, B. & Gallardo, J. M. (2009). Mass spectrometry characterization of

species-specific peptides from arginine kinase for the identification of

commercially relevant shrimp species. Journal of Proteome Research, 8, 5356–

5362.

 

Paldaviciene, A., Zaiko, A., Mazur-Marzec, H. & Razinkovas-Baziukas, A. (2015).

Bioaccumulation of microcystins in invasive bivalves: A case study from the

boreal lagoon ecosystem. Oceanologia, 57, 93-101.

 

Papadimitriou, T., Kagalou, I., Stalikas, C., Pilidis, G. & Leonardos, I. D. (2012).

Assessment of microcystin distribution and biomagnification in tissues of

aquatic food web compartments from a shallow lake and evaluation of potential

risks to public health. Ecotoxicology, 21, 1155-1166.

 

Parker, S. L., Leznoff, A., Sussman, G. L., Tarlo, S. M. & Krondl, M. (1990).

Characteristics of patients with food-related complaints. Journal of Allergy and

Clinical Immunology, 86, 503-511.

 

Paschke, A. (2009). Aspects of food processing and its effect on allergen structure.

Molecular Nutrition and Food Research, 53 (8), 956-962.

 

Pasini, G., Simonato, B., Giannattasio, M., Peruffo, A. D. B. & Curioni, A. (2001).

Modifications of wheat flour proteins during in vitro digestion of bread dough,

crumb, and crust: An electrophoretic and immunological study. Journal of

Agricultural and Food Chemistry, 49 (5), 2254-2261.

 

Passali, D., Bellusi, L. M., Kern, E. B., Sarafoleanu, C. & Popescu, F. D. (2013).

Genes, allergens and inflammation in allergic rhinitis. In: Rhinosinusal

inflammation and infections: modern thinking and current treatment. Bucharest:

Editura Academiei Romane, pp101-167.

 

Pastorello, E. A. & Trambaioli, C. (2001). Isolation of food allergens. Journal of

Chromatography B: Biomedical Sciences and Applications, 756 (1-2), 71-84.

 

Patelis, A., Borres, M. P., Kober, A. & Berthold, M. (2016). Multiplex componentbased

allergen microarray in recent clinical studies. Clinical and Experimental

Allergy, doi: 10.1111/cea.12761.

 

Pathansali, D. (1966). Notes on the biology of the cockle, Anadara granosa.

Proceedings of the Indo-Pacific Fisheries Council, 11, 84-98.

 

Peakman, M. & Vergani, D. (1997). Basic and clinical immunology, Pearson

Professional Limited. pp. 136.

 

Peng, L., Liu, Y., Chen, W., Liu, L., Kent, M. & Song, L. (2010). Health risks

associated with consumption of microcystin-contaminated fish and shellfish in

three Chinese lakes: significance for freshwater aquacultures. Ecotoxicology and

Environmental Safety, 73, 1804-1811.

 

Perry, T. T., Matsui, E. C., Conover-Walker, M. K. & Wood, R. A. (2004). Risk of

oral food challenge. Journal of Allergy and Clinical Immunology, 114 (5), 1164-

1168.

 

Pham, T. L., Shimizu, K., Kanazawa, A., Gao, Y., Dao, T. S. & Utsumi, M. (2016).

Microcystin accumulation and biochemical responses in the edible clam

Corbiculaleana P. exposed to cyanobacterial crude extract. Journal of

Environmental Sciences (China), 44, 120-130.

 

Pham, T. L., Shimizu, K., Dao, T. S., Hong-Do, L. C. & Utsumi, M. (2015).

Microcystin uptake and biochemical responses in the freshwater clam Corbicula

leana P. exposed to toxic and non-toxic Microcystis aeruginosa: Evidence of

tolerance to cyanotoxins. Toxicology Reports, 2, 88-98.

 

Ponnusamy, K., Sivaperumal, P., Suresh, M., Arularasan S., Munilkumar, S. & Pal,

A. K. (2014). Heavy metal concentration from biologically important edible

species of bivalves (Perna viridis and Modiolus metcalfei) from Vellar Estuary,

South East Coast of India. Journal of Aquaculture Research and Development,

5, 5.

 

Popescu, F-D. (2015). Cross-reactivity between aeroallergens and food allergens.

World Journal of Methodology, 5 (2), 31-50.

 

Potasman, I., Paz, A. & Odeh, M. (2002). Infectious outbreaks associated with bivalve

shellfish consumption: a worldwide perspective. Clinical Infectious Diseases, 35

(8), 921-928.

 

Pourhoseingholi, M. A., Vahedi, M. & Rahimzadeh, M. (2013). Sample size

calculation in medical studies. Gastroenterology and Hepatology from Bed to

Bench, 6 (1), 14-17.

 

Poutiers, J. M. (1998). Bivalves: Acephala, Lamellibranchia, Pelecypoda. In:

Carpenter K.E., Niem V.H (eds.) The Living Marine Resources of the West

Central Pacific. Vol. 1, Seaweeds, Corals, Bivalves and Gastropods. FAO

Species Identification Guide for Fishery Purpose. Rome: Food and Agriculture

Organization of the United Nations. pp. 123-362.

 

Quirce, S., Marañón, F., Umpiérrez, A., de las Heras, M., Fernández-Caldas, E. &

Sastre, J. (2001). Chicken serum albumin (Gal d 5*) is a partially heat-labile

inhalant and food allergen implicated in the bird-egg syndrome. Allergy, 56,

754-762.

 

Rabilloud, T. (2000). Proteome research: two-dimensional gel electrophoresis and

identification methods, Springer Verlag. pp. 33.

 

Radauer, C., Bublin, M., Wagner, S., Mari, A. & Breiteneder, H. (2008). Allergens

are distributed into few protein families and possess a restricted number of

biochemical functions, Journal of Allergy and Clinical Immunology, 121, 847-

852.

 

Raikos, V., Hansen, R., Campbell, L. & Euston, S. R. (2006). Separation and

identification of hen egg protein isoforms using SDS-PAGE and 2D gel

electrophoresis with MALDI-TOF mass spectrometry. Food Chemistry, 99 (4),

702-710.

 

Rajagopal, S., Venugopalan, V. P., van der Velde, G. & Jenner, H. A. (2006).

Greening of the coasts: a review of the Perna viridis success story. Aquatic

Ecology, 40, 273-297.

 

Rance, F., Grandmottet, X. & Grandjean, H. (2005). Prevalence and main

characteristics of school children diagnosed with food allergies in France.

Clinical and Experimental Allergy, 35, 167-172.

 

Rashid, R. S., Smith, K. A., Nambiar, K. Z., Frew, A. J. & Tarzi, M. D. (2011).

Pollen-food syndrome is related to Bet v 1/PR-10 protein sensitisation, but not

all patients have spring rhinitis. Allergy, 66, 1391-1392.

 

Rao, J. N., Rivera-Santiago, R., Li, X. E., Lehman, W. & Dominguez, R. (2012).

Structural analysis of smooth muscle tropomyosin alpha and beta isoforms.

Journal of Biological Chemistry, 287, 3165-3174.

 

Reese, G., Ayuso, R. & Lehrer, S. B. (1999). Tropomyosin: an invertebrate panallergen.

International Archives of Allergy and Immunology, 119 (4), 247-258.

 

Ring, J. (2006). Allergy in practice. Springer Science & Business Media. pp. 44.

 

Rippey, S. R. (1994). Infectious diseases associated with molluscan shellfish

consumption. Clinical Microbiology, 7 (4), 419-425.

 

Roberts, G., Ollert, M., Aalberse, R., Austin, M., Custovic, A., DunnGalvin, A., et al.

(2016). A new framework for the interpretation of IgE sensitization tests.

Allergy, doi: 10.1111/all.12939.

 

Rochanaburanon, T. (1980). A comparison of macronutrient levels in green mussel

(Perna viridis) and brown mussel (Modiolus metcalfei Hanley). Journal of the

Science Society of Thailand, 6 (4), 191-197.

 

Rodriguez-Del Rio, P., Sanchez-Lopez, J., Robledo Echarren, T., Martinez-Cocera, C.

& Fernandez-Rivas, M. (2009). Selective allergy to Venus antiqua clam.

Allergy, 64 (5), 815.

 

Rosmilah, M., Shahnaz, M., Zailatul, H. M. Y., Noormalin, A. & Normilah, I. (2012).

Identification of tropomyosin and arginine kinase as major allergens of Portunus

pelagicus (blue swimming crab). Tropical Biomedicine, 29 (3), 467-478.

 

Roux, K. H., Teuber, S. S. & Sathe, K. K. (2003). Tree nut allergens. International

Archives of Allergy and Immunology, 131 (4), 234-244.

 

Sahabudin, S., Misnan, R., Yadzir, Z. H. M., Mohamed, J., Abdullah, N., Bakhtiar, F.,

et al. (2014). Characterization of major and minor allergens of sharp-rostrum

prawn (Parapenaeopsis hardwickii). The Experiment, 19 (4), 1367-1374.

 

Sahabudin, S., Misnan, R., Yadzir, Z. H., Mohamad, J., Abdullah, N., Bakhtiar, F., et

al. (2011). Identification of major and minor allergens of black tiger prawn

(Penaeus monodon) and king prawn (Penaeus latisulcatus). Malaysian Journal

of Medical Sciences, 18 (3), 27-32.

 

Salcedo, G., Sanchez-Monge, R., Diaz-Perales, A., Garcia-Casado, G. & Barber, D.

(2004). Plant non-specific lipid transfer proteins as food and pollen allergens.

Clinical and Experimental Allergy, 34 (9), 1336-1341.

 

Saleh-Langenberg, J., Flokstra-de Blok, B. M., AlAgla, N., Kollen, B. J. & Dubois, A.

E. (2016). Late reactions in food-allergic children and adolescents after doubleblind,

placebo-controlled food challenges. Allergy, 71 (7), 1069-1073.

 

Sancho, A. I. & Mills, E. N. (2010). Proteomic approaches for qualitative and

quantitative characterisation of food allergens. Regulatory Toxicology and

Pharmacology, 58 (3), S42-46.

 

Sander, I., Flagge, A., Merget, R., Halder, T. M., Meyer, H. E. & Baur, X. (2001).

Identification of wheat flour allergens by means of 2-dimensional

immunoblotting. Journal of Allergy and Clinical Immunology, 107 (5), 907-913.

 

Sastre, J. (2010). Molecular diagnosis in allergy. Clinical and Experimental Allergy,

40 (10), 1442-1460.

 

Sathe, S. K. & Sharma, G. M. (2009). Effect of food processing on food allergens.

Molecular Nutrition and Food Research, 53 (8), 970-978.

 

Sathe, S. K., Teuber, S. S. & Roux, K. H. (2005). Effects of food processing on the

stability of food allergens. Biotechnology Advances, 23, 423-429.

 

Savi, E., Rossi, A. & Incorvaia, C. (2006). Cat-pork syndrome: a case report with a

three years follow-up. European Annals of Allergy and Clinical Immunology,

38, 366-368.

 

Schmid-Grendelmeier, P. & Crameri, R. (2001). Recombinant allergens for skin

testing. International Archives of Allergy and Immunology, 125 (2), 96-111.

 

Shanti, K. N., Martin, B. M., Nagpal, S., Metcalfe, D. D. & Subba Rao, P.V. (1993).

Identification of tropomyosin as the major shrimp allergen and characterization

of its IgE-binding epitopes. Journal of Immunology, 151, 5354-5363.

 

Shek, L., Cabrera-Morales, E. A., Soh, S. E., Gerez, I., Ng, P. Z., Yi, F. C., et al.

(2010). A population-based questionnaire survey on the prevalence of peanut,

tree nut and shellfish allergy in 2 Asian populations. Journal of Allergy and

Clinical Immunology,126, 324-331.

 

Shen, Y., Cao, M. J., Cai, Q. F., Su, W. J., Yu, H. L., Ruan, W. W., et al. (2011).

Purification, cloning, expression and immunological analysis of Scylla serrata

arginine kinase, the crab allergen. Journal of Science and Food Agriculture, 91

(7), 1326-1335.

 

Shriver, S. K. & Yang, W. W. (2011). Thermal and nonthermal methods for food

allergen control. Food Engineering Reviews, 3, 26-43.

 

Shore, S. A., Schwartzman, I. N., Mellema, M. S., Flynt, L., Imrich, A. & Johnston,

R. A. (2005). Effect of leptin on allergic airway responses in mice. Journal of

Allergy and Clinical Immunology, 115 (1), 103–109.

 

Sicherer, S. H. (2001). Clinical implications of cross-reactive food allergens. Journal

of Allergy and Clinical Immunology, 108, 881-890.

 

Sicherer, S. H. & Sampson, H. A. (2010). Food allergy. Journal of Allergy and

Clinical Immunology, 125 (2), S116-S125.

 

Simonato, B., Pasini, G., Giannattasio, M., Peruffo, A. D. B., De Lazzari, F. &

Curioni, A. (2001). Food allergy to wheat products: The effect of bread baking

and in vitro digestion on wheat allergenic proteins. A study with bread dough,

crumb, and crust. Journal of Agricultural and Food Chemistry, 49 (1), 5668-

5673.

 

Simpson, A., Lazic, N., Belgrave, D. C. M., Johnson, P., Bishop, C., Mills, C., et al.

(2015). Patterns of IgE responses to multiple allergen components and clinical

symptoms at age 11 years. Journal of Allergy and Clinical Immunology, 136,

1224-1231.

 

Singh, Y.T., Krishnamoorthy, M. & Thippeswamy, S. (2012). Seasonal changes in the

biochemical composition of wedge clam, Donax scortum from the Padukere

beach, Karnataka. Recent Research in Science and Technology, 4 (12), 12-17.

 

Skamstrup, H. K., Vestergaard, H., Stahl, S. P., SØndergaard, K. M., Vieths, S.,

Poulsen, L. K. et al. (2001). Double-blind, placebo-controlled food challenge

with apple. Allergy, 56, 109-117.

 

Skypala, I. J., Bull, S., Deegan, K., Gruffydd-Jones, K., Holmes, S., Small, I., et al.

(2013). The prevalence of PFS and prevalence and characteristics of reported

food allergy; a survey of UK adults aged 18-75 incorporating a validated PFS

diagnostic questionnaire. Clinical and Experimental Allergy, 43, 928-940.

 

Sood, A., Ford, E. S. & Camargo, Jr. C. A. (2006). Association between leptin and

asthma in adults. Thorax, 61 (4), 300–305.

 

Sookrung, N., Chaicumpa,W., Tungrongchitr, A., Vichyanond, P., Bunnag, C.,

Ramasoota, P., et al. (2006). Periplaneta americana arginine kinase as a major

cockroach allergen among Thai patients with major cockroach allergies.

Environmental Health Perspectives, 114, 875–880.

 

Sulkowska, M., Golaszewska, J., Wincewicz, A., Koda, M., Baltaziak, M. &

Sulkowski, S. (2006). Leptin-from regulation of fat metabolism to stimulation of

breast cancer growth. Pathology and Oncology Research, 12 (2), 69-72.

 

Suzuki, M., Kobayashi, Y., Hiraki, Y., Nakata, H. & Shiomi, K. (2011). Paramyosin

of the disc abalone Haliotis discus discus: Identification as a new allergen and

cross-reactivity with tropomyosin. Food Chemistry, 124, 921-926.

 

Syed, A., Kohli, A. & Nadeau, K. C. (2013). Food allergy diagnosis and therapy.

Immunotherapy, 5 (9), 931-944.

 

Szépfalusi, Z., Ebner, C., Pandjaitan, R., Orlicek, F., Scheiner, O., Boltz-Nitulescu,

G., et al. (1994). Egg yolk alpha-livetin (chicken serum albumin) is a crossreactive

allergen in the bird-egg syndrome. Journal of Allergy and Clinical

Immunology, 93, 932-942.

 

Taheri-Kafrani, A., Gaudin, J. C., Rabesona, H., Nioi, C., Agarwal, D., Drouet, M., et

al. (2009). Effects of heating and glycation of beta-lactoglobulin on its

recognition by IgE of sera from cow milk allergy patients. Journal of

Agricultural and Food Chemistry, 57, 4974-4982.

 

Taylor, S. L. (2008). Molluscan shellfish allergy. Advances in Food and Nutrition

Research, 54,139-177.

 

Thammathongchat, S., Hagiwara, T. & Sakiyama, T. (2010). Adsorption of

tropomyosin from pink shrimp (Pandalus eous) on stainless steel surface. Food

Control, 21 (9), 1250-1253.

 

Thomas, K., Herouet-Guicheney, C., Ladics, G., Bannon, G., Cockburn, A., Crevel,

R., et al. (2007). Evaluating the effect of food processing on the potential human

allergenicity of novel proteins: International workshop report. Food and

Chemical Toxicology, 45 (7), 1116-1122.

 

Tomikawa, M., Suzuki, N., Urisu, A., Tsuburai, T., Ito, S., Shibata, R., et al. (2006).

Characteristics of shrimp allergy from childhood to adulthood in Japan. Arerugi,

55, 1536-1542.

 

Towbin, H., Staehelin, T. & Gordon, J. (1979). Electrophoretic transfer of proteins

from polyacrylamide gels to nitrocellulose sheets: procedure and some

applications. Proceedings of the National Academy of Sciences, 76 (9), 4350–

4354.

 

Traidl-Hoffmann, C., Jakob, T. & Behrendt, H. (2009). Determinants of allergenicity.

Journal of Allergy and Clinical Immunology, 123, 558-566.

 

Tungtrongchitr, A., Sookrung, N., Indrawattana, N., Sae-Lim, J., Punduang, S.,

Phonrat, B., et al. (2009). Seasonal levels of the major American cockroach

allergen Per a 9 (arginine kinase) in Bangkok and their relevance for disease

severity. Asian Pacific Journal of Allergy and Immunology, 27, 1–7.

 

Valenta, R. (2002). The future of antigen-specific immunotherapy of allergy. Nature

Reviews Immunology, 2, 446-453.

 

Valenta, R., Lidholm, J., Niederberger, V., Hayek, B., Kraft, D. & Grönlund, H.

(1999). The recombinant allergen-based concept of component-resolved

diagnostics and immunotherapy (CRD and CRIT). Clinical and Experimental

Allergy, 29, 896-904.

 

Van Ree, R., Antonicelli, L., Akkerdaas, J. H., Pajno, G. B., Barberio, G., Corbetta,

L., et al. (1996). Asthma after consumption of snails in house-dust-mite-allergic

patients: a case of IgE cross-reactivity. Allergy, 51 (6), 387-393.

 

Venkatesan, V. & Mohamed, K. S. (2015). Bivalve classification and taxonomy.

Available from: eprints.cmfri.org.in

 

Verhoeckx, K. C. M., Vissers, Y. M., Boumert, J. L., Faludi, R., Feys, M., Flanagan,

S., et al. (2015). Food processing and allergenicity. Food and Chemical

Toxicology, 80, 223-240.

 

Verma, A. K., Kumar, S., Das, M. & Dwivedi, P. D. (2012). Impact of thermal

processing on legume allergens. Plant Foods for Human Nutrition, 67, 430-441.

 

Vickery, B. P., Chin, S. & Burks, A. W. (2011). Pathophysiology of food allergy.

Pediatric Clinic of North America, 58, 363-376.

 

Vickery, B. P., Scurlock, A. M., Jones, S. M. & Burks, A. W. (2011). Mechanisms of

immune tolerance relevant to food allergy. Journal of Allergy and Clinical

Immunology, 127, 576-584.

 

Vieira, V. J., Ronan, A. M., Windt, M. R. & Tagliaferro, A. R. (2005). Elevated atopy

in healthy obese women. American Journal of Clinical Nutrition, 82 (3), 504-

509.

 

Vieths, S., Scheurer, S. & Ballmer-Weber, B. (2002). Current understanding of crossreactivity

of food allergens and pollen. Annals of the New York Academy of

Sciences, 964, 47-68.

 

Vieths, S., Hoffmann, A., Holzhauser, T., Müller, U., Reindl, J. & Haustein, D.

(1998). Factors influencing the quality of food extracts for in in vitro and in vivo

diagnosis. Allergy, 53 (46), 65-71.

 

Villas, F., Compes, E., Fernández-Nieto, M., Muñoz M. P., Bartolome, B. & de las

Heras, M. (2009). Bird-egg syndrome caused by Agapornis species (lovebird).

Journal of Investigational Allergology and Clinical Immunology, 19, 71-72.

 

Wang, C., Chai, X., Wang, H., Tang, B. & Liu, B. (2013). Growth performance of the

clam, Meretrix meretrix, breeding-selection populations cultured in different

conditions. Acta Oceanologica Sinica, 32 (10), 82-87.

 

Woo, C. K. & Bahna, S. L. (2011). Not all shellfish “allergy” is allergy!. Clinical and

Translational Allergy, 1, 3.

 

Woods, R. K., Abramson, M., Bailey, M. & Walters, E. H. (2001). International

prevalence of reported food allergies and intolerances. Comparisons arising

from the European Community Respiratory Health Survey (ECRHS) 1991-

1994. European Journal of Clinical Nutrition, 55, 298-304.

 

Wright, D. J., Leach, I. B. & Wilding, P. (1977). Differential scanning calorimetric

studies of muscle and its constituents. Journal of the Science of Food and

Agriculture, 28 (6), 557-564.

 

Wu, A. Y. & Williams, G. A. (2004). Clinical characteristics and pattern of skin test

reactivities in shellfish allergy patients in Hong Kong. Allergy and Asthma

Proceedings, 25, 237-242.

 

Xiong, Y. L. & Blanchard, S. P. (1994). Dynamic gelling properties of myofibrillar

protein from skeletal muscles of different chicken parts. Journal of Agricultural

and Food Chemistry, 42 (3), 670-674.

 

Xu, C., Lin, X., Ren, H., Zhang, Y., Wang, S. & Peng, X. (2006). Analysis of outer

membrane proteome of Escherichia coli related to resistance to ampicillin and

tetracycline. Proteomics, 6 (2), 462-473.

 

Yadzir, Z. H. M., Misnan, R., Abdullah, N., Bakhtiar, F., Arip, M. & Murad, S.

(2012a). Identification of the major allergen of Macrobrachium rosenbergii

(giant freshwater prawn). Asian Pacific Journal of Tropical Biomedicine, 2 (1),

50-54.

 

Yadzir, Z. H. M., Misnan, R. & Murad, S. (2012b). Identification of tropomyosin as

major allergen of white squid (Loligo edulis) by two-dimensional

immunoblotting and mass spectrometry. Southeast Asian Journal of Tropical

Medicine and Public Health, 43 (1), 185-191.

 

Yadzir, Z. H. M., Misnan, R., Abdullah, N., Bakhtiar, F., Arip, M. & Murad, S.

(2010). Identification of IgE-binding proteins of raw and cooked extracts of

Loligo edulis (white squid). Southeast Asian Journal of Tropical Medicine and

Public Health, 41 (3), 653-659.

 

Yagami, T., Haishima, Y., Tsuchiya, T., Tomitaka-Yagami, A., Kano, H. &

Matsunaga, K. (2004). Proteomic analysis of putative latex allergens.

International Archives of Allergy and Immunology, 135, 3-11.

 

Yamatomo, T., Okano, M., Ono, T., Nakayama, E., Yoshino, T., Satoskar, A. R., et al.

(2001). Sex-related differences in the initiation of allergic rhinitis in mice.

Allergy, 56 (6), 525–531.

 

Yap, C. K., Tan, S. G., Ismail, A. & Omar, H. (2004). Allozyme polymorphisms and

heavy metal levels in the green-lipped mussel Perna viridis (Linnaeus) collected

from contaminated and uncontaminated sites in Malaysia. Environment

International, 20 (1), 39-46.

 

Yokoyama, A. & Park, H. D. (2003). Depuration kinetics and persistence of the

cyanobacterial toxin microcystin-LR in the freshwater bivalve Unio douglasiae.

Environmental Toxicology, 18, 61-67.

 

Yu, C. J., Lin, Y. F., Chiang, B. L. & Chow, L. P. (2003). Proteomics and

immunological analysis of a novel shrimp allergen, Pen m 2. Journal of

Immunology, 170, 445-453.

 

Zahedi, F. D., Gendeh, B. S. & Husain, S. (2011). Sensitization to common allergens

in children with allergic rhinitis. Brunei International Medical Journal, 7 (4),

200-206.

 

Zinn, C., Lopata, A., Visser, M. & Potter, P. C. (1997). The spectrum of allergy to

South African bony fish (Teleosti). Evaluation by double-blind, placebocontrolled

challenge. South African Medical Journal, 87, 146-152.

 

Zuberbier, T., Edenharter, G., Worm, M., Ehlers, I., Reimann, S., Hantke, T., et al.

(2004) Prevalence of adverse reactions to food in Germany-a population study.

Allergy, 59, 338-345.

 

Zuidmeer-Jongejan, L., Fernandez-Rivas, M., Poulsen, L., Neubauer, A., Asturias, J.,

Blom, L., et al. (2012). FAST: Towards safe and effective subcutaneous

immunotherapy of persistent life-threatening food allergies. Clinical and

Translational Allergy, 2 (1), 5.

 


This material may be protected under Copyright Act which governs the making of photocopies or reproductions of copyrighted materials.
You may use the digitized material for private study, scholarship, or research.

Back to previous page

Installed and configured by Bahagian Automasi, Perpustakaan Tuanku Bainun, Universiti Pendidikan Sultan Idris
If you have enquiries with this repository, kindly contact us at pustakasys@upsi.edu.my or Whatsapp +60163630263 (Office hours only)