Molecularly imprinted polymeric microspheres for electrochemical sensing of cholesterol

Ulianas, Alizar

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Type :	article
Subject :	Q Science (General)
ISSN :	0974-1496
Main Author :	Ulianas, Alizar
Additional Authors :	Mohamad Syahrizal Ahmad Illyas Md Isa
Title :	Molecularly imprinted polymeric microspheres for electrochemical sensing of cholesterol

Place of Production :	Tanjung Malim
Publisher :	Fakulti Sains dan Matematik
Year of Publication :	2021
Notes :	Rasayan Journal of Chemistry
Corporate Name :	Universiti Pendidikan Sultan Idris
HTTP Link :	Click to view web link

Abstract : Universiti Pendidikan Sultan Idris

An electrochemical cholesterol sensor based on emulsion photo-polymerized methacrylic acid molecularly imprinted polymers (MIPs) microspheres modified screen-printed electrode (SPE) has been developed. Electrochemical quantitation of cholesterol concentration was performed by means Cyclic Voltammetry (CV) and Square Wave Voltammetry (SWV) technique by using redox couple of potassium ferricyanide [K3Fe(CN)6]. A decrement in the electrochemical CV and SWV signal indicated that the cholesterol molecules were bound to the microspheres? cavities of the biomimetic MIPs sensor, and formed an electron transfer barrier to the redox species from electron transfer at the electrode surface. Under optimal conditions, the electrochemical MIPs microsensor could detect cholesterol concentration in the linear response range of 0.5 mg L-1 to 50.0 mg L-1 with a limit of detection (LOD) at 0.1 mg L-1. The MIPs microspheres-modified carbon SPE electrode providing good operational stability to cholesterol sensing of up to 11 days long. ? 2021, Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma. All rights reserved.

References

Ahmad, M. S., Isa, I. M., Hashim, N., Saidin, M. I., Si, S. M., Zainul, R., . . . Mukdasai, S. (2019). Zinc layered hydroxide-sodium dodecyl sulphate-isoprocarb modified multiwalled carbon nanotubes as sensor for electrochemical determination of dopamine in alkaline medium. International Journal of Electrochemical Science, 14(9), 9080-9091. doi:10.20964/2019.09.54

Azis, N. A., Isa, I. M., Hashim, N., Ahmad, M. S., Mohd Yazid, S. N. A., Saidin, M. I., . . . Mukdasai, S. (2019). Voltammetric determination of bisphenol a in the presence of uric acid using a zn/al-ldh-qm modified MWCNT paste electrode. International Journal of Electrochemical Science, 14(11), 10607-10621. doi:10.20964/2019.11.46

Bautista-Ruiz, J., Aperador, W., & Joya, M. R. (2020). Electrochemical impedance, cyclic voltammetry, and corrosive behavior in TiO2 nanostructures. Rasayan Journal of Chemistry, 13(4), 2092-2098. doi:10.31788/RJC.2020.1345854

Brüggemann, O. (2002). Molecularly imprinted materials--receptors more durable than nature can provide. Advances in Biochemical Engineering/Biotechnology, 76, 127-163. doi:10.1007/3-540-45345-8_4

Danielsson, B. (2007). Artificial receptors doi:10.1007/10_2007_088 Retrieved from www.scopus.com

Deswati, Suyani, H., Zein, R., Pardi, H., Buchari, & Setiyanto, H. (2020). Analysis method of anti-cancer drug semustine for chemotherapy by cyclic voltammetry. Rasayan Journal of Chemistry, 13(4), 2045-2051. doi:10.31788/RJC.2020.1345845

Futra, D., Heng, L. Y., Jaapar, M. Z., Ulianas, A., Saeedfar, K., & Ling, T. L. (2016). A novel electrochemical sensor for 17β-estradiol from molecularly imprinted polymeric microspheres and multi-walled carbon nanotubes grafted with gold nanoparticles. Analytical Methods, 8(6), 1381-1389. doi:10.1039/c5ay02796a

Ji, J., Zhou, Z., Zhao, X., Sun, J., & Sun, X. (2015). Electrochemical sensor based on molecularly imprinted film at au nanoparticles-carbon nanotubes modified electrode for determination of cholesterol. Biosensors and Bioelectronics, 66, 590-595. doi:10.1016/j.bios.2014.12.014

Li, L. -., Dutkiewicz, E. P., Huang, Y. -., Zhou, H. -., & Hsu, C. -. (2019). Analytical methods for cholesterol quantification. Journal of Food and Drug Analysis, 27(2), 375-386. doi:10.1016/j.jfda.2018.09.001

Ma, X., & Chen, M. (2015). Electrochemical sensor based on graphene doped gold nanoparticles modified electrode for detection of diethylstilboestrol. Sensors and Actuators, B: Chemical, 215, 445-450. doi:10.1016/j.snb.2015.04.016

Mulyasuryani, A., & Savitri, A. (2015). Jurnal Kimia VALENSI: Jurnal Penelitian Dan Pengembangan Ilmu Kimia, 1, 97. Retrieved from www.scopus.com

Pavia, D. L., Lampman, G. M., & Kriz, G. S. (1996). Introduction to Spectroscopy, Retrieved from www.scopus.com

Sellergren, B., & Shea, K. J. (1993). Influence of polymer morphology on the ability of imprinted network polymers to resolve enantiomers. Journal of Chromatography A, 635(1), 31-49. doi:10.1016/0021-9673(93)83112-6

Wang, J. (2000). Analytical Electrochemistry, 2, 121. Retrieved from www.scopus.com

Yang, H., Li, L., Ding, Y., Ye, D., Wang, Y., Cui, S., & Liao, L. (2017). Molecularly imprinted electrochemical sensor based on bioinspired au microflowers for ultra-trace cholesterol assay. Biosensors and Bioelectronics, 92, 748-754. doi:10.1016/j.bios.2016.09.081

Yusof, N. A., Beyan, A., Haron, J., & Ibrahim, N. A. (2010). Synthesis and characterization of a molecularly imprinted polymer for Pb2+ uptake using 2-vinylpyridine as the complexing monomer. Sains Malaysiana, 39(5), 829-835. Retrieved from www.scopus.com

Zhai, Y., Liu, Y., Chang, X., Chen, S., & Huang, X. (2007). Selective solid-phase extraction of trace cadmium(II) with an ionic imprinted polymer prepared from a dual-ligand monomer. Analytica Chimica Acta, 593(1), 123-128. doi:10.1016/j.aca.2007.04.040

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