This study aimed to synthesize and characterise the homogenous chitosan/hydroxyapatite (CS/HA) composite by in situ precipitation method. The optimum ratio of chitosan/hydroxyapatite composite was studied by varying the concentration of chitosan, orthophosphoric acid (H3PO4) and calcium nitrate (Ca(NO3)2.4H2O) used in this formulation. The CS-H3PO4 solution was prepared and reacted with Ca(NO3)2.4H2O to produce CS/HA composites ratio of 30/70, 40/60 and 45/55, which were identified by thermogravimetric analysis. Fourier transform infrared spectroscopy results showed absorption peaks at 601.8 cm-1 and 562.0 cm-1 to 564.2 cm-1 which proved the presence of phosphate, PO43- of HA component whereas absorption peak at 1591.0 cm-1 was corresponding to amide of the chitosan group. Scanning electron microscopy analysis on the composite surface revealed that CS/HA composite with 45/55 ratio exhibited particles with needle like shape with cross-section of 5.41 nm and length of 37.2 nm distributed.....

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