This study performed to investigate the chemical compounds, toxicology, in vitro and in  vivo  antioxidant  capacity  of  Malaysian  Peperomia  pellucida  plant  towards  ICR mice.   The  qualitative  chemical  compound  test  was  performed  and  the  antioxidant capacity of P.  pellucida plant extract was analyzed by 2,2-diphenyl-1-picrylhydrazyl (DPPH),  β-carotene   bleaching  and  oxygen  radical  absorbance  capacity  (ORAC) assays. The in vivo sub-acute  toxicity study that used the best solvent from  in vitro assay was done using ICR mice which were  randomly divided. The different doses of 50 mg/kg, 150 mg/kg, 200 mg/kg, 500 mg/kg and 1000 mg/kg  body weight of extract were administered daily for 21 days to the treated mice. The antioxidant  enzymes in liver and kidney of mice were investigated using standard assays.  P. pellucida only  exhibited the presence of alkaloid, phenol and saponin. The ability to scavenge free radical i.....

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