Agarwood is a type of wood that originated from an Aquilaria tree. It is considered to be a highly valuable resin that formed inside the main stem. The tree belongs in the Thymelaeaceae family and there are numerous types of Aquilaria tree available. The common ones are Aquilaria malaccensis, Aquilaria sinensis, Aquilaria crassna, and Aquilaria subintegra due to its being favoured among planters. In order to avoid any wastage, planters used various parts of the Aquilaria tree such as the leaves, stem, bark and root to produce various types of agarwood products (i.e.oud oil,agarwood tea, and incense). Based on the extensive researches that had been carried out, it was discovered that the agarwood or Aquilaria tree possess various medicinal properties, such as anticancer, anti-inflammatory, analgesics, antidiabetic, antihistaminic, antianxiety, antibacterial, hepatoprotective, laxative, and improved neural activity. Although agarwood contained various medicinal properties, there are stil.....

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The study was conducted to investigate the acute toxicity of aqueous extract from Aquilaria malaccensis (AMAE) and Aquilaria subintegra (ASAE) leaves and their histological effects on several organ in ICR mice. Comparison between both extracts was included in order to determine which toxicity is more potent. A total of 156 ICR mice was used in this study consisted of 78 male and 78 female with the age of 12 weeks old. The mice were divided into 13 groups containing 12 mice (6 males and 6 females) in each group. 12 groups orally received one type of extract either AMAE or ASAE with only one type concentration. The concentrations used were 4000, 5000, 6000, 7000, 8000, 9000 mg/kg body weight. One group on the other hand act as the control and treated with distilled water. Extract administration was conducted only once on the first day. Mice body weight and organ weight were compared and analyzed using one-way ANOVA and evaluation of abnormalities in term of appearance and beha.....

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