This research aimed to prepare, characterise and study the effectiveness of two magnetic graphene oxide-based nanocomposites, namely gellan gum-graphene oxide (GG-GO-Fe3O4) and pectin-graphene oxide (PEC-GO-Fe3O4) as nanocarriers for permethrin and cinnamaldehyde insecticide compounds. This research is divided into three parts, namely preparation, characterisation and effectiveness studies. Nanocomposites with amorphous structure were successfully produced based on the existence of conjugation mechanism between GG and PEC with iron oxide at wavenumber peak 650 cm-1. Results from thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) have shown that the nanocomposites loaded with insecticides are thermally stable. Performance study of nanocomposites loaded with insecticides towards Aedes aegypti larvae was analysed through Abbott’s and Probit’s formula via in vitro at different pH using ultraviolet-visible (UV-Vis) spectrometer. The encapsulation o.....

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Magnetic nanoparticles have evolved over the last few decades as nanocarriers in drug delivery systems for hydrophobic drugs. Here, novel gellan gum magnetic graphene oxide (GG-GO-Fe3O4) and pectin magnetic graphene oxide (PEC-GOFe3O4) nanocomposites were prepared to carry cinnamaldehyde to control Aedes aegypti larvae. Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM) and scanning transmission electron microscopy (STEM) were employed to investigate the physicochemical characteristics of the nanocomposites. Entrapment efficiencies and loading capacities of nanocomposites on cinnamaldehyde were examined using ultraviolet-visible analysis. The successful cinnamaldehyde loading was confirmed by C-C and C-O stretches in the FTIR spectra. Results of in vitro release study showed the capabilities of GG-GO-Fe3O4 as a drug carrier system, extending the cinnamaldehyde release period for 36 h, and the release profiles for both nanocomposites fit .....

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