UPSI Digital Repository (UDRep)
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Abstract : Universiti Pendidikan Sultan Idris |
In the present study, the efficacy of gellan gum-magnetic graphene oxide (GG-GO-Fe3O4) and pectin-magnetic graphene oxide (PEC-GO-Fe3O4) nanocomposites as nanocarriers for permethrin to control Aedes aegypti larvae was investigated for the first time. The physicochemical properties of the nanocomposites were studied using various scientific instruments. The ability of GG-GO-Fe3O4 and PEC-GO-Fe3O4 to load and release permethrin in vitro system was determined using an ultravioletvisible (UVVis) spectrometer. FTIR analysis has demonstrated the change in intensity and wavenumber of absorption bands, confirming the successful encapsulation of permethrin into the nanocarriers. Based on STEM analysis, the highest increment in size of nanocarriers (85%) was obtained after permethrin loading. The nanocarriers prolonged the release of permethrin up to 16h. The release profiles of permethrin from nanocarriers in rainwater were best fitted by Korsmeyer-Peppaskinetic model with correlation coefficient (R2) values of greater than 0.9522 for the mass ratio of permethrin:nanocarriers at 1:5, 1:15 and 1:25. Based on Abbotts formula and Probit analysis, the LC50 values for permethrin were between 3.72 and 11.12mg/L. The application of permethrin:GG-GO-Fe3O4 at mass ratio of 1:25 exhibited the highest mortality percentage of 88.20% following 72h exposure to A. aegypti larvae. 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. |
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