Chemical composition and acetylcholinesterase activity of syzygium pyrifolium (Blume) DC. Essential Oil

Wan Mohd Nuzul Hakimi Wan Salleh

Abstract

This study aims to investigate the chem-ical composition and acetylcholinesterase activity of essential oil from Syzygium pyrifolium leaves. The es-sential oil was obtained by hydrodistillation in a Clevenger-type apparatus and its chemical composi-tion was analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Thirty-two volatile components were identified in S. pyrifolium leaves oil, including geraniol (73.8%), ?-pinene (7.0%), ?-pinene (5.7%) and (E)-?-ocimene (4.5%) as the major components. Acetylcholinester-ase activity was evaluated using Ellman method and the essential oil showed strong inhibitory activity (I%: 82.5%). Our findings demonstrate that S. pyri-folium essential oil could be useful for an alternative raw material of food and medicinal products for pharmaceutical applications. 2023, Latin American Applied Research. All Rights Reserved.

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