Chemical composition and acetylcholinesterase activity of syzygium pyrifolium (Blume) DC. Essential Oil

Wan Mohd Nuzul Hakimi Wan Salleh

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Type :	article
Subject :	Q Science (General)
ISSN :	0327-0793
Main Author :	Wan Mohd Nuzul Hakimi Wan Salleh
Title :	Chemical composition and acetylcholinesterase activity of syzygium pyrifolium (Blume) DC. Essential Oil

Place of Production :	Tanjung Malim
Publisher :	Fakulti Sains dan Matematik
Year of Publication :	2023
Notes :	Latin American Applied Research
Corporate Name :	Universiti Pendidikan Sultan Idris
HTTP Link :	Click to view web link

Abstract : Universiti Pendidikan Sultan Idris

This study aims to investigate the chem-ical composition and acetylcholinesterase activity of essential oil from Syzygium pyrifolium leaves. The es-sential oil was obtained by hydrodistillation in a Clevenger-type apparatus and its chemical composi-tion was analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Thirty-two volatile components were identified in S. pyrifolium leaves oil, including geraniol (73.8%), ?-pinene (7.0%), ?-pinene (5.7%) and (E)-?-ocimene (4.5%) as the major components. Acetylcholinester-ase activity was evaluated using Ellman method and the essential oil showed strong inhibitory activity (I%: 82.5%). Our findings demonstrate that S. pyri-folium essential oil could be useful for an alternative raw material of food and medicinal products for pharmaceutical applications. 2023, Latin American Applied Research. All Rights Reserved.

References

Adams, R.P. (2007) Identification of essential oil compo-nents by gas chromatography-mass spectrometry. 4th ed. Carol Stream (IL): Allured Publishing Corporation.

Aung, E.E., Kristanti, A.N., Aminah, N.S., Takaya, Y. and Ramadhan, R. (2020) Plant description, phyto-chemical constituents and bioactivities of Syzygium genus: A review. Open Chem. 18, 1256-81.

Batiha, G.E., Alkazmi, L.M., Wasef, L.G., Beshbishy, A.M., Nadwa, E.H. and Rashwan, E.K. (2020) Syzyg-ium aromaticum L. (Myrtaceae): Traditional uses, bi-oactive chemical constituents, pharmacological and toxicological activities. Biomolecules. 10, 202-218.

Cheraif, K., Bakchiche, B., Gherib, A., Bardaweel, S.K., Çol Ayvaz, M., Flamini, G., Ascrizzi and R., Ghareeb, M.A. (2020) Chemical composition, antiox-idant, anti-tyrosinase, anti-cholinesterase and cyto-toxic activities of essential oils of six Algerian plants. Molecules. 25, 1710.

Chen, W. and Viljoen, A.M. (2020) Geraniol - A review of a commercially important fragrance material. S Afr. J. Bot. 76, 643-51.

da Costa, J.S., da Cruz, E.N.S., Setzer, W.N., da Silva, J.K.D.R., Maia, J.G.S. and Figueiredo, P.L.B. (2020) Es-sentials oils from Brazilian Eugenia and Syzygium species and their biological activities. Biomolecules, 10, 1-36.

Kochummen, K.M. (1978) Myrtaceae. Tree Flora of Ma-laya. 3, 169-254

Maczka, W., Winska, K. and Grabarczyk, M. (2020) One hundred faces of Geraniol. Molecules. 25, 3303.

Marucci, G., Buccioni, M., Ben, D.D., Lambertucci, C., Volpini, R. and Amenta, F. (2021) Efficacy of acetyl-cholinesterase inhibitors in Alzheimer's disease. Neu-ropharmacology. 190, 108352.

Mukherjee, P.K., Kumar, V., Mal, M. and Houghton, P.J. (2007) Acetylcholinesterase inhibitors from Plants. Phytomedicine. 14, 289-300.

Orhan, I., Aslan, S., Kartal, M., Şener, B. and Husnu Can Başer, K. (2008) Inhibitory effect of Turkish Rosma-rinus officinalis L. on acetylcholinesterase and butyr-ylcholinesterase enzymes. Food Chem. 108, 663-668.

Parnell, J. and Chantaranothai, P. (2002) Myrtaceae. Flora of Thailand. 7, 778-914.

Rahman, M.A., Ali, A., Hasan, N.F., Khandaker, M.M. and Mat, N. (2018) Morphological and anatomical studies of Syzygium polyanthum (Wight) Walp. (Myr-taceae). Malayan Nat. J. 70, 309-322.

Salleh, W.M.N.H.W., Ahmad, F., Khong, H.Y. and Zulkifli, R.M. (2016a). Anticholinesterase and anti-inflammatory constituents from Beilschmiedia pul-verulenta Kosterm. Nat. Prod. Sci., 22, 225-230.

Salleh, W.M.N.H.W., Ahmad, F., Khong, H.Y. and Zulkifli, R.M. (2016b) Comparative study of the essen-tial oils of three Beilschmiedia species and their bio-logical activities. Int. J. Food Sci. Tech. 51, 240-249.

Vernin, G., Vernin, G., Metzger, J., Roque, C. and Pieri-battesti, J.C. (1991). Volatile constituents of the jam-rosa aroma Syzygium jambos L. Aston from Reunion Island. J. Essent. Oil Res. 3, 83-97.

Wong, K.C. and Lai, F.Y. (1996). Volatile constituents from the fruits of four Syzygium species grown in Ma-laysia. Flav. Fragr. J. 11, 61-66.

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