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Chemical composition, anti-tyrosinase activity and molecular docking studies of knema malayana warb. essential oil

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General Information
Title
Chemical composition, anti-tyrosinase activity and molecular docking studies of knema malayana warb. essential oil
Type
Article
Main Author
Wan Mohd Nuzul Hakimi Wan Salleh
Subject
Q Science (General)
ISSN
0972-060X
Language Code
eng
Bibliographic Details
Place of Production
Tanjung Malim
Publisher
Fakulti Sains dan Matematik
Year of publication
2023
Notes
Journal of Essential Oil-Bearing Plants
Degree Type
Not related
Corporate Name
Universiti Pendidikan Sultan Idris

Abstract

Essential oils produced from aromatic plants denote significant biological activities and are gaining prominence in scientific research. In this study, the chemical composition, anti-tyrosinase activity, and molecular docking studies of Knema malayana Warb. essential oil was investigated. A hydrodistillation method was used to produce the essential oil, characterised by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC/MS). Additionally, anti-tyrosinase activity was evaluated against mushroom tyrosinase, while molecular docking studies were performed with the major components. A total of 38 components (98.9%) were successfully identified in the essential oil, which was characterised by high proportions of ?-cadinene (20.2%), ?-cadinol (13.7%), ?-amorphene (10.3%), ?-cadinene (6.3%), ?-gurjunene (5.3%), ?-gurjunene (5.3%), and ?-muurolene (5.0%). The essential oil demonstrated moderate activity towards tyrosinase activity with an IC50 value of 85.3 ?g/mL. Consequently, the best docking energy was observed with ?-amorphene (-6.9 Kcal/mol), which successfully formed interactions with His263, Phe264, and Val283. These interactions were essential amino acid residues of the tyrosinase receptor. 2023 Har Krishan Bhalla & Sons.

References

Salleh, W.M.N.H.W., Shakri, N.M., Khamis, S., Setzer, W.N. and Nadri, M.H. (2022). Chemical composition of three Malaysian Horsfieldia essential oils. Nat. Prod. Res. 36(7): 1909-1913.

Salleh, W.M.N.H.W., Khamis, S., Nafiah, M.A. and Abed, S.A. (2021). Chemical composition and anticholinesterase inhi-bitory activity of the essential oil of Pseuduvaria macrophylla (Oliv.) Merr. from Malaysia. Nat. Prod. Res. 35(11): 1887-1892.

Shakri, N.M., Salleh, W.M.N.H.W., Khamis, S. and Ali, N.A.M. (2020). Composition of the essential oils of three Malaysian Xylopia species (Annonaceae). Z. Naturforsch. C J. Biosci. 75(11-12): 479-484.

Pascal, J.P. and Pelissier, R. (1996). Structure and floristic composition of a tropical evergreen forest in South-West India. J. Trop. Ecol. 12(2): 191-214.

Pinto, M.M.M. and Kijjoa, A. (1990). Chemical study of Knema species from Thailand. Quim. Nova. 13(4): 243-244.

Kijjoa, A., Gonzalez, M.J., Pinto, M., Monanondra, I.O. and Herz, W. (1991). Constituents of Knema laurina and Knema tenuinervia ssp setosa. Planta Med. 57(6): 575-577.

Gonzalez, M.J., Deoliveira, C.J.C., Fernandes, J.O., Kijjoa, A. and Herz, W. (1996). Further alkyl and alkenylphenols of Knema laurina and Knema austrosiamensis: location of the double bond in the alkenyl side chains. Phytochemistry. 43(6): 1333-1337.

Wenli, M., Yong, Y., Wei, N. and Chang-Xiang, C. (2000). Flavonoids from Knema globularia. Acta Bot. Yunnan. 22(3): 358-360.

Sinclair, J. (1961). The genus Knema (Myristicaceae) in Malaysia and outside Malaysia. Singapore: Garden Bulletin.

De Wilde, W. (1998). More Notes on Knema and Myristica (Myristicaceae). Blumea. 43(1): 241-254.

Wiart, C., Mogana, S., Khalifah, S., Mahan, M., Ismail, S., Buckle, M., Narayana, A. K. and Sulaiman, M. (2004). Antimicrobial screening of plants used for traditional medicine in the state of Perak, Peninsular Malaysia. Fitoterapia. 75(1): 68-73.

Ismail, N.H., Jaafar, F.M., Ahmat, N., Ahmad, R. and Hana, N. (2008). Phyto-chemical and biological activity screening of plants collected from Kuala Keniam, Taman Negara, Pahang. In Proceeding of National Biodiversity Seminar, pp. 77-85.

Seo, S.Y., Sharma, V.K. and Sharma, N. (2003). Mushroom tyrosinase: recent pros-pects. J. Agric. Food Chem. 51: 2837-2853.

Asanuma, M., Miyazaki, I. and Ogawa, N. (2003). Dopamine- or L-DOPA-induced neurotoxicity: the role of dopamine quinone formation and tyrosinase in a model of Parkinson’s disease. Neurotox. Res. 5: 165-176.

Friedman, M. (1996). Food browning and its prevention: an overview. J. Agric. Food Chem. 44: 631-653.

Matsuura, R., Ukeda, H. and Sawamura, M. (2006). Tyrosinase inhibitory activity of citrus essential oils. J. Agric. Food Chem. 54: 2309-2313.

Adams, R.P. (1995). Identification of Essen-tial Oil Components by Gas Chromatography/Mass Spectroscopy. Allured Publishing Co. Carol Stream, Illinois.

Salleh, W.M.N.H.W. and Khamis, S. (2021). Chemical composition and tyrosinase inhibitory activity of the essential oil of Rhodamnia cinerea. Chem. Nat. Compd. 57: 770-771.

Abbas, Q., Ashraf, Z., Hassan, M., Nadeem, H., Latif, M., Afzal, S. and Seo, S.Y. (2017). Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies. Drug Des. Dev. 11: 2029-2046.

Hassan, M., Vanjare, B.D., Sim, K.Y., Raza, H., Lee, K.H., Shahzadi, S. and Kloczkowski, A. (2022). Biological and cheminformatics studies of newly designed triazole based derivatives as potent inhibitors against mushroom tyrosinase. Molecules. 27: 1731-1744.

Salleh, W.M.N.H.W., Anuar, M.Z.A., Khamis, S., Nafiah, M.A. and Sul’ain, M.D. (2021). Chemical investigation and biological activities of the essential oil of Knema kunstleri Warb. from Malaysia. Nat. Prod. Res. 35(13): 2279-2284.

Thinh, B.B., Khoi, N.T., Doudkin, R.V., Thin, D.B. and Ogunwande, I.A. (2023). Chemical composition of essential oil and antioxidant activity of the essential oil and methanol extracts of Knema globularia (Lam.) Warb. from Vietnam. Nat. Prod. Res. 37(10): 1625-1631.

Salleh, W.M.N.H.W., Ahmad, F., Khong, H.Y. and Zulkifli, R.M. (2016). Comparative study of the essential oils of three Beilschmiedia species and their biological activities. Int. J. Food Sci. Technol. 51: 240-249.

Almeida, L.Q., Do Nascimento, L.D., Da Costa, F.A.M., Da Costa, K.S. and Andrade, E.H.D.A. (2022). In vitro anti-bacterial activity and in silico analysis of the bioactivity of major compounds obtained from the essential oil of Virola surinamensis Warb (Myristicaceae). J. Food Qual. 5275805.

Mesquita, R.D.S., de Oliveira, A.C., Sá, I.S.C., Sales, M.L.F., Bastos, L.M., Koolen, H.H.F., Tadei, W., da Silva, F.M.A. and Nunomura, R.C.S. (2020). Essential oils from leaves of Virola calophylla, Virola multinervia, and Virola pavonis (Myristicaceae): Chemical composition and larvicidal activity against Aedes aegypti. J. Essent. Oil Bear. Plants. 23(3): 453-463.

Dang, J.L., Yang, X.B., Huang, Y.F., Ye, F., Luo, T., Chen, S.L., Liu, B. and Bai, Y.F. (2009). GC-MS analysis on the chemical constituents of essential oil from bark of Horsfieldia hainanensis. J. Chinese Med. Mat. 32(5): 714-716.

Ashokkumar, K., Simal-Gandara, J., Murugan, M., Dhanya, M.K. and Pandian, A. (2022). Nutmeg (Myristica fragrans Houtt.) essential oil: A review on its composition, biological, and pharmacological activities. Phytother. Res. 36(7): 2839-2851.

da Silva, N.H., Paciencia, M.L.B., Frana, S.A., Díaz, I.E.C. and Suffredini, I.B. (2020). Antibacterial activity of essential oils from leaves of Iryanthera ulei Warb. (Myristicaceae): A temporal analysis pers-pective. J. Essent. Oil Bear. Plants. 23(5): 890-901.

Agnaniet, H., Makani, T., Menut, C. and MarieBessiere, J. (2004). Aromatic plants of tropical central Africa. Part LI chemical and biological investigation of essential oils from seeds and bark of Staudtia gabonensis Warb. J. Essent. Oil Bear. Plants. 7(2): 107-112.

Prasad, K.N., Yang, B., Yang, S., Chen, Y., Zhao, M., Ashraf, M. and Jiang, Y. (2009). Identification of phenolic compounds and appraisal of antioxidant and antityrosinase activities from litchi (Litchi sinensis Sonn.) seeds. Food Chem. 116: 1-7.

Dilshad, R., Khan, K.R., Ahmad, S., Aati, H.Y., Al-qahtani, J.H., Sherif, A.E. and Ahmed, M. (2022). Phytochemical pro-filing, in vitro biological activities, and in-silico molecular docking studies of Typha domingensis. Arab. J. Chem. 15: 104133.


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