UPSI Digital Repository (UDRep)
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UPSI Digital Repository (UDRep)
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| Abstract : Universiti Pendidikan Sultan Idris |
| Objectives: This study investigates the impact of injected fish-scale-derived hydroxyapatite nanoparticles (FsHA-NPs) on orthodontic tooth movement (OTM) and the width of the periodontal ligament (PDL) space. Materials and Methods: Twenty-six Wistar rats underwent mesial orthodontic traction with a force of 50 g for 21 days. Following the application of the orthodontic appliance, the rats were randomly divided into two groups: a control group, which received a 0.3 _g saline injection, and the experimental FsHA group, which received 100 mg/0.3 ml of FsHA-NPs after thorough characterisation. Injections were administered immediately after appliance application and repeated at 7 and 14 days. Statistical analysis was conducted with a significance level of P _ 0.05. Result: The experimental group exhibited a significant reduction in OTM at 7-, 14-, and 21-day post-force application. Additionally, a reduction in PDL width was observed in the mesiocervical and disto-apical regions of the mesial and distal roots of the first molar. Conclusion: FsHA-NPs derived from biowaste fish scales exhibit promising potential as biomaterials for enhancing control over OTM. This study underscores the viability, accessibility, and safety of FsHA-NPs as a locally injectable material for orthodontic applications. _ 2024 |
| References |
Alhasyimi, A.A., Pudyani, P.S., Asmara, W., et al., 2017. Locally inhibition of orthodontic relapse by injection of carbonated hydroxy apatite-advanced platelet rich fibrin in a rabbit model. Key Eng. Mater. 758, 255-263. https://doi.org/10.4028/www.scientific.net/KEM.758.255. Alhasyimi, A., Pudyani, P., Asmara, W., et al., 2018. Enhancement of post-orthodontic tooth stability by carbonated hydroxyapatite-incorporated advanced platelet-rich fibrin in rabbits. Orthod. Craniofac. Res. 21, 112-118. https://doi.org/10.1111/ocr.12224. Alhasyimi, A.A., Suparwitri, S., Christnawati, C., 2021. Effect of carbonate apatite hydrogel-advanced platelet-rich fibrin injection on osteoblastogenesis during orthodontic relapse in rabbits. Eur. J. Dent. 15, 412-419. https://doi.org/10.1055/s-0040-1721234. Al-Rahim, A.M., Mahmood, R.I., Mohammed, M.M., et al., 2022. In vitro evaluation of antioxidant and cytotoxic activity of folate-methotrexate conjugated to bovine serum albumin nanoparticles against MCF-7, HepG2, and PC3 cell lines. Gene Rep. 29, 101666 https://doi.org/10.1016/j.genrep.2022.101666. Crawford, D., Lau, T.C., Frost, M.C., et al., 2022. Control of orthodontic tooth movement by nitric oxide releasing nanoparticles in Sprague-Dawley rats. Front. Mater. Sci. 9, 811251 https://doi.org/10.3389/fmats.2022.811251. Espitia-Quiroz, L.C., Fern_andez-Orjuela, A.L., Anaya-Sampayo, L.M., et al., 2022. Viability and adhesion of periodontal ligament fibroblasts on a hydroxyapatite Scaffold combined with collagen, polylactic acid-polyglycolic acid copolymer and platelet-rich fibrin: A preclinical pilot study. Dent. J. 10, 167. https://doi.org/10.3390/dj10090167. Franzen, T.J., Brudvik, P., Vandevska-Radunovic, V., 2013. Periodontal tissue reaction during orthodontic relapse in rat molars. Eur. J. Orthod. 35, 152-159. https://doi.org/10.1093/ejo/cjr127. Gani, A., Yulianty, R., Supiaty, S., et al., 2022. Effectiveness of combination of chitosan gel and hydroxyapatite from crabs shells (Portunus pelagicus) waste as bonegraft on periodontal network regeneration through IL-1 and BMP-2 analysis. Int. J. Biomater. 2022 https://doi.org/10.1155/2022/1817236. Hara, A. T., J. C. Carvalho and D. T. Zero, 2015. Causes of dental erosion: extrinsic factors. Dental Erosion and Its Clinical Management. B. T. Amaechi: 69-96. Haraguchi, K., 2015. Application of CL/P Nanocomposites. Encyclopedia of Polymeric Nanomaterials. S. Kobayashi and K. Mullen. Berlin, Heidelberg, Springer Berlin Heidelberg: 49-57. Kaipatur, N., Wu, Y., Adeeb, S., et al., 2014. A novel rat model of orthodontic tooth movement using temporary skeletal anchorage devices: 3D finite element analysis and in vivo validation. Int. J. Dent. 2014 https://doi.org/10.1155/2014/917535. Khan, A.S., Alshaia, A., AlDubayan, A., et al., 2022. Preparation of nano-apatite grafted glass-fiber-reinforced composites for orthodontic application: Mechanical and in vitro biofilm analysis. Materials 15, 3504. https://doi.org/10.3390/ma15103504. Liao, Y., Li, H., Shu, R., et al., 2020. Mesoporous hydroxyapatite/chitosan loaded with recombinant-human amelogenin could enhance antibacterial effect and promote periodontal regeneration. Front. Cell. Infect. Microbiol. 10, 180. https://doi.org/10.3389/fcimb.2020.00180. Mahmood, R. I., H. S. Mohammed-Salih, A. a. Ghazi, et al., 2024. Exploring the potential of copper oxide biogenic synthesis: a review article on the biomedical and dental implementations. Arab Gulf J. Sci. Res. 42, 370-387. Doi: 10.1108/AGJSR-12-2022-0315. Majhooll, A.A., Zainol, I., Jaafar, C.N.A., et al., 2019. Preparation of fish scales hydroxyapatite (FsHAp) for potential use as fillers in polymer. J. Chem. Chem. Eng. 13, 97-104. https://doi.org/10.17265/1934-7375/2019.03.002. Malik, S.S.S., Ghaib, N.H., 2017. The effect of nano-hydroxy apatite on re-mineralize white spot lesions prior to orthodontic adhesive removal by different techniques (An In vitro comparative study). J. Baghdad College Dent. 29, 90-96. https://doi.org/10.12816/0038756. Mohammed-Salih, H. S., H. A. Al-Lami, H. F. Saloom, et al., 2023. Detection of orthodontically induced inflammatory root resorption-associated biomarkers from the gingival crevicular fluid by proteomics analysis: a randomized-controlled clinical trial. 3 Biotech. 13, 157. Doi: 10.1007/s13205-023-03572-5. Mohammed-Salih, H.S., Saloom, H.F., 2022. Collection, storage and protein extraction method of gingival crevicular fluid for proteomic analysis. Baghdad Sci. J. 19, 0368. https://doi.org/10.21123/bsj.2022.19.2.0368. Mudhafar, M., Zainol, I., Alsailawi, H., et al., 2023. Preparation and characterization of FsHA/FsCol beads: Cell attachment and cytotoxicity studies. Heliyon 9. https://doi.org/10.1016/j.heliyon.2023.e15838. Padmanabhan, S.K., Balakrishnan, A., Chu, M.-C., et al., 2009. Sol-gel synthesis and characterization of hydroxyapatite nanorods. Particuology 7, 466-470. https://doi.org/10.1016/j.partic.2009.06.008. Pathomkulmai, T., Chanmanee, P., Samruajbenjakun, B., 2022. Effect of extending corticotomy depth to trabecular bone on accelerating orthodontic tooth movement in rats. Dent. J. 10, 158. https://doi.org/10.3390/dj10090158. Percie du Sert, N., Hurst, V., Ahluwalia, A., et al., 2020. The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research. J. Cereb. Blood Flow Metab. 40, 1769-1777. https://doi.org/10.1177/0271678X20943823. Refaat, M.M., Hamad, T.I., 2016. Evaluation of mechanical and histological significance of nano hydroxyapatite and nano zirconium oxide coating on the osseointegration of CP Ti implants. J. Baghdad College Dent. 28 https://doi.org/10.12816/0031105. Retrouvey, J.-M. and K. Kousaie, 2021. Basic Mechanics Applied to Orthodontics, International Foundation for Dental Education. Sathiskumar, S., Vanaraj, S., Sabarinathan, D., et al., 2019. Green synthesis of biocompatible nanostructured hydroxyapatite from Cirrhinus mrigala fish scale-A biowaste to biomaterial. Ceram. Int. 45, 7804-7810. https://doi.org/10.1016/j.ceramint.2019.01.086. Sun, W., Chu, C., Wang, J., et al., 2007. Comparison of periodontal ligament cells responses to dense and nanophase hydroxyapatite. J. Mater. Sci. Mater. Med. 18, 677-683. https://doi.org/10.1007/s10856-006-0019-8. Swidi, A.J., Taylor, R.W., Tadlock, L.P., et al., 2018. Recent advances in orthodontic retention methods: A review article. J. World Fed. Orthod. 7, 6-12. https://doi.org/10.1016/j.ejwf.2018.01.002. |
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