UPSI Digital Repository (UDRep)
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Abstract : Perpustakaan Tuanku Bainun |
Over a few decades ago, meta-analysis has rapidly developed in various fields of studies to improve
the quality of previous research by quantitative review. Quantitative review assesses an overall
magnitude of the effect from multiple studies. Hence, the objective in this dissertation is to
determine the methods of finding effect sizes for different conditions in meta-analysis. Two key
findings of this study are as follows: Firstly, vote-counting method will be applied if the effect
size estimates are not available. Next, fixed effects and random effects methods will be used in
combining the effect size estimates when effect size estimates can be calculated. 55 Randomised
Controlled Trials (RCTs) on Tamoxifen treatment for early breast cancer patients are observed
according to recurrences and mortality cases, respectively. The data is then analysed by using
the latest statistical software, Comprehensive Meta-Analysis (CMA) version 2.0. CMA is found to be
beneficial and interactive in the process of meta-analysis. The selection bias as well as the
publication bias should be avoided in order to produce better quality meta-analysis.
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