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Hernagine type of Aporphine Alkaloids from Alseodaphne perakensis

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Title
Hernagine type of Aporphine Alkaloids from Alseodaphne perakensis
Type
Article
Main Author
Md Nazimuddin Mahfuzah, Husna Hasnan Muhammad Hafiz, Ahmad Kartini, Awang Khalijah, Nafiah Mohd Azlan,
Subject
QD Chemistry
ISSN
2289-7070
Language Code
eng
Bibliographic Details
Place of Production
N/A
Year of publication
2014

Abstract

A phytochemical study of the stem bark of Alseodaphne perakensis (Lauraceae) had been carried out. The dichloromethane crude extract from stem bark of Alseodaphne perakensis (Lauraceae) yielded two hernagine type of aporphine alkaloids namely oxohernagine and N-methylhernagine. The isolation and purification of these alkaloids were achieved using Column Chromatography (CC) and Preparative Thin Layer Chromatography (PTLC) techniques. The structural elucidations were performed by spectral methods notably Nuclear Magnetic Resonance (NMR) Spectroscopy one-dimentional (1H, 13C and DEPT) and two-dimentional (COSY, HMQC/HSQC and HMBC).
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