Preparation and characterisation of carvacrol encapsulated in Gellan Gum Hydrogel (IR)

Hasnu Norafida, Mohd Azam Nur Aisyah Nasuha, Mohamad Jaafar Adila,

QR Code Link :
Type :	article
Subject :	QD Chemistry
ISSN :	2289-7070
Main Author :	Hasnu Norafida, Mohd Azam Nur Aisyah Nasuha, Mohamad Jaafar Adila,
Title :	Preparation and characterisation of carvacrol encapsulated in Gellan Gum Hydrogel (IR)

Place of Production :	Universiti Pendidikan Sultan Idris
Year of Publication :	2017
PDF Full Text :	Login required to access this item.

Full Text :

Studies on plant materials as natural compound such as carvacrol (Carv) have gained much attention. Carv exhibits numerous potential as antimicrobial agent, food additives, antioxidant and etc. However, this free standing bioactive compound is unstable in the harsh environment conditions. Hence, the encapsulation technology provides protection to enhance the effectiveness in release manner. In this study, the preparation of Carv encapsulated in gellan gum hydrogel forming thin film (GG-Carv TF) was achieved by using 1.0 g of gellan gum at different concentrations of Carv (0.01-0.04 M). The FTIR spectra of GG-Carv TF revealed the combination of both functional groups from GG and Carv. The Carbon, Hydrogen and Nitrogen, CHN analysis further confirmed the encapsulation with the changes in the element percentage. Both swelling and degradation percentage increased with time and showed decreasing patterns in the range of 680.79-666.78 % and 26.83-19.15 % which can be observed as the concentration of Carv increased, respectively.

References

1. Nostro A., Roccaro, A. S., Bisignano, G., Marino, A. and Blanco, A.R. (2007). Effect of oregano, Carvacrol and Thymol on S. aureus and S. epidermdis biofilms. J. Med. Microbiol. 56: 591-523. 2. Chami, F., Chami, N., Bennis, S., Bouchikhi, T., and Remmal, A. (2005). Oregano and clove essential oils induce surface alteration of Saccharomyces cerevisiae. Phytother. Res. 19:405- 408. 3. Arfa, B.A., Combes, S., Preziosi-Belloy, L., Gontard, N., and Chalier, P. (2006). Antimicrobial activity of carvacrol related to its chemical structure. Lett.in Appl. Microbiol. 43:149-154. 4. Oussalah, M., Caillet, S., Saucier, L., and Lacroix, M. (2007). Inhibitory effects of selected plant essential oils on the growth of four pathogenic bacteria: E. coli O157:H7, Salmonella Typhimurium, Staphylococcus aureus and Listeria monocytogenes. Food Control. 18:414-420. 5. Ravishankar, S., Zhu, L., Reyna-Granados, J., Law, B., Joens, L., and Friedman, M. (2010). Carvacrol and cinnamaldehyde inactivate antibiotic-resistant Salmonella enterica in buffer and on celery and oysters. J. Food Prot. 73:234-240. 6. Perez-Conessa, D., Cao, J., Chen, L., Mclandsborough, L., and Weiss, J. (2011). Inactivation of Listeria monocytogenes and Escherichia coli O157:H7 biofilms by micelle encapsulated eugenol and carvacrol. J. Food Prot. 74:55-62. 7. Han J. H.,Krochta, J. M., Kurth, M. J., and Hsieh, Y. L. (2000). Lactitol-based poly (ether polyol) hydrogels for controlled release chemical and drug delivery systems. Journal of Agricultural and Food Chemistry. 48(11), 5278-5282. 8. Kang D., Zhang, H. B., Nitta, Y., Fang, Y. P., & Nishinari, K. (2015). Gellan. Polysaccharides: Bioactivity and Biotechnology. 1627-1682. 9. Chalier P., A.B. Arfa, L.P. Belloy and N. Gontard. (2007). Carvacrol losses from soy protein coated papers as a function of drying conditions. Journal of Applied Polymer Science. 106: 611-620. 10. Pourjavadi A., Kurdtabar M. (2007). Collagen-based highly porous hydrogel without any porogen: Synthesis and characteristics. European Polymer Journal. 43: 877-889. 11. Veldhuizen, E. J. A., Tjeerdsma-Van Bokhoven, J.L.M., Zweijtzer, C., Burt, S.A., and Haagsman, H.P. (2006). Structural requirements for the antimicrobial activity of carvacrol. J. Agric. Food Chem. 54:1874-1879. 12. Oliveira J. T., Santos T. C., Martins L., Picciochi R, Marques A. P., Castro A. G. (2010). Gellan gum injectable hydrogels for cartilage tissue engineering applications: in vitro studies and preliminary in vivo evaluation. Tissue Eng Part A. 16 (1):343-353. 13. Daniela F. Coutinho, Shilpa V. S., HyeonghoS., João T. O., Manuela E. G., Nuno M. N., Ali K., and Rui L. R. (2010). Modified Gellan Gum hydrogels with tunable physical and mechanical properties. Journal Biomaterials. 31: 7494-7502.

This material may be protected under Copyright Act which governs the making of photocopies or reproductions of copyrighted materials.
You may use the digitized material for private study, scholarship, or research.

Back to previous page