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Type :thesis
Subject :RA Public aspects of medicine
Main Author :Mai Shihah Abdullah
Title :Epidemiologi pensensitifan alergi makanan, inhalan dan produk apikultur terhadap darjah kesensitifan dari perspektif atopik dan persekitaran bagi penduduk di Tanjong Malim, Perak (IR)
Place of Production :Tanjong Malim
Publisher :Fakulti Sains dan Matematik
Year of Publication :2010
Notes :doctoral
Corporate Name :Universiti Pendidikan Sultan Idris
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Abstract : Universiti Pendidikan Sultan Idris
Epidemiological studies pensensitifan allergens allergic three groups consisting of food , inhalan and apiculture products was conducted among residents Tanjong Malim , Perak . A total of 2523 respondents , including 141 indigenous population ( 41.4 % male , 58.5 % female : 30.8 % of children , 69.2 % adults : 94.4 % of the population urban , rural 5.6% ) were interviewed and underwent skin prick test . A total of 633 complete data index of mother, father and siblings were used to Familial aggregation test model . Design ex post facto correlation using a questionnaire to obtain information from the self- reporting respondents . Questionnaires were divided into five groups with two ( familial and symptoms) represents a factor of atopic booster while three others ( settlements , style life and behavior ) represents an environment encouraging factors . Panel battery test containing 43 allergens ( 19 meals , 9 and 15 inhalan apiculture products ) used to test for allergic sensitivity respondents. All allergens were apiculture products provided its own and is only used after standardization carried out in accordance with ID50FAL correlation method and basophils histamine protein profiles and reviews . for the purpose of verifying the origins of apiculture products , pollen studies with techniques asetolisis melisopalinologi conducted. The study found 8 allergens have been successful apiculture products standardized . 51.1% of respondents reported a history of allergic sensitivity , 53.7% and 54.9% of familial history of having symptoms while the prevalence of allergies allergic pensensitifan true for only 37.9 % of this population only. Between 86.5 % -44.8 % of respondents reported living in an environment dusty , berlipas , cloudy , with a prevalence protect pets and furry doll . The prevalence of allergic sensitivity according to the show respectively 34 % rural : urban 38.07 % ; 40.15 % male : 36.22 % females, and 35 % of children : 38.9 % of adults . Pensensitifan general population to inhalan is 30.4 % , food 20.4 % and 11.2% of apiculture products . The main trigger food allergy sensitivity is crab ( 10.74 % ) , shrimp ( 5.91 % ) and mussels ( 1.98 % ) . Inhalan major allergens are house dust mites are , Dermatophagoides pteronyssinus (12.64 % ) , D. farinae ( 12:52 % ) , a mixture of both ( 11:41 % ) , animal dander ( 9:27 % ) and cockroach ( 8.68 % ) . Major allergen products Apiculture consist of the issuance of the honey bee ( 3.85 % ) , honey bee pollen ( 1.28% ) and honey bees ( 0.67 % ) . Inhalan is a key indicator of the cause of respondents This study gets allergy sensitivity ( adjusted R2 = .555 , β = .745 , p < .000 ) . Domestic crowding provide coordinated R2 = .005 , β = - .078 , p < .007 give implications for the probability that a protective effect on the population . comparison general population and the prevalence of atopic to pensensitifan degrees is 37.9% : 100 % ( monosensitifan ) : 20.3 % : 53.5 % ( dwisensitifan ) and 5.4 % : 14.3 % ( trisensitifan ) . Relationship with degrees pensensitifan booster factor shows that atopic Symptomatic [ F ( 1.2521 ) = 245 430 , p < .000 , R2 = .089 ) , a key indicator increase the degree of sensitivity followed atopic familial factors , environmental triggers and residential space in the general population . Familial aggregation model shows atopic parents familial relationship is a significant risk factor OR = 3.618 ( 2537 - 5158 , CI 95 % ) , no significant atopic mothers OR = 1338 ( .925-1.933 , CI 95 % ) and adikberadik Atopic significant only if beragregasi with atopic mothers OR = 1569 ( 1.012 - 2433 , CI 95 % ) . Familial relationship atopic parents give risk factors OR = 2578 ( 1837-3618 , 95 % CI ) . Respondents who are atopic baby birth March is the month of the birth cohort of the highest. phase birth cohort was found to clash with the peak growth of dust mites minor home in April and again majors in November-January . study index case also shows familial atopic factor is a major contributor to pensensitifan degrees [ F ( 1,631 = 18:42 , p < .000 , R2 = .028 ) . Stepwise regression environment shows encouraging factors is not the sole factor significant contribution to the degree of allergic pensensitifan R2 = .008 ( p < .254 ) . The study found that providing familial atopic factors predisposing traits to pensensititifan allergy needs to be stimulated in the amount and duration of exposure by a degree of environmental factors that distinguish an allergic sensitivity . In conclusion , exposure hypothesis is applicable to residents of Tanjong Malim.
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