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The genus Alphonsea belongs to the family Annonaceae, which comprises of about 30 species, consisting of small trees and shrubs are distributed in China and Indo-Malayan. In this mini review, we aim to provide an overview of the traditional uses, biological activities and phytochemistry of plants Alphonsea sp. Literature, abstract and full text articles from journals, books, reports and electronic searches as well as from other relevant websites are surveyed, analysed and included in this review. The crude extracts exhibit anti-cancer, anti-oxidant, anti-fungal, anti-inflammatory and anti-trypanasomal activities. The survey reveled that Alphonsea sp. contain alkaloids, steroids, lignan, sesquiterpenes and monoterpenes.
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