Phytochemistry and biological activities of the Genus Knema (Myristicaceae) (IR)

Wan Salleh Wan Mohd Nuzul Hakimi, Ahmad Farediah,

QR Code Link :
Type :	article
Subject :	Q Science (General)
ISSN :	1735-403X
Main Author :	Wan Salleh Wan Mohd Nuzul Hakimi, Ahmad Farediah,
Title :	Phytochemistry and biological activities of the Genus Knema (Myristicaceae) (IR)

Place of Production :	CrossMark
Year of Publication :	2017
PDF Full Text :	The author has requested the full text of this item to be restricted.

Full Text :

Knema, a genus of the family Myristicaceae, usually found in Southeast Asia, has been used to treat sores, pimples, rheumatism, and cancer. A compilation of the research on isolation, structure elucidation, structural diversity, and bioactivities of Knema secondary metabolites reported between 1978 and 2016 are included in this review. Up to now, the reported constituents from the genus Knema included acetophenone, substituted stilbene, lignan, flavonoid,alkyl/acyl resorcinol, and phenylalkylphenol derivatives. Studies showed that Knema and its active principles possessed a wide range of biological activities such as antibacterial, antinematodal, anti-inflammatory, cytotoxicity, and acetylcholinesterase inhibitory activities. The increasing amounts of data support the application and exploitation for new drug development.

References

1. Smitinand T. Thai Plant Names. Revised Edition. Bangkok: Prachachon; 2001. 2. Perry LM. Medicinal Plants of East and Southeast Asia: Attributed Properties and Uses.1st Edition. Cambridge:MIT Press; 1980. 3. Spencer GF, Tjarks LW, Kleiman R. Alkyl and phenylalkyl anacardic acids from Knema elegans seed oil. J Nat Prod. 1980;43(6):724-30.doi:10.1021/np50012a005 4. Pinto MMM, Kijjoa A. Chemical study of Knema species from Thailand. Quim Nova. 1990;13(4):243-4. 5. Gonzalez MJ, Deoliveira CJC, Fernandes JO, Kijjoa A, Herz W. Further alkyl and alkenylphenols of Knema laurina and Knema austrosiamensis: location of the double bond in the alkenyl side chains. Phytochemistry. 1996;43(6):1333-7. doi:10.1016/s0031-9422(96)00413-x 6. Kijjoa A, Gonzalez MJ, Pinto M, Monanondra IO, Herz W. Constituents of Knema laurina and Knema tenuinervia ssp setosa. Planta Med. 1991;57(06):575-7. doi:10.1055/s-2006-960210 7. Pinto M, Kijjoa A, Mondranondra IO, Gutierrez AB, Hertz W. Lignans and other constituents of Knema furfuracea. Phytochemistry.1990;29(6):1985-8. doi:10.1016/0031-9422(90)85052-h 8. Wenli M, Yong Y, Wei N, Chang-Xiang C. Flovonoids from Knema globularia. Acta Botanica Yunnanica. 2000;22(3):358-60. 9. Zahir A, Jossang A, Bodo B, Hadi HA, Schaller H, Sevenet T. Knerachelins A and B, antibacterial phenylacylphenols from Knema furfuracea. J Nat Prod. 1993;56(9):1634-7.doi:10.1021/np50099a031 10.Alen Y, Nakajima S, Nitoda T, Baba N, Kanzaki H, Kawazu K. Antinematodal activity of some tropical rainforest plants against the pinewood nematode, Bursaphelenchus xylophilus. Z Naturforsch C. 2000;55(34):295-9.doi:10.1515/znc-2000-3-425 11.Rangkaew N, Suttisri R, Moriyasu M, Kawanishi K. A new arylnaphthalene lignan from Knema furfuracea. Fitoterapia. 2009;80(6):377-9. doi:10.1016/j.fitote.2009.05.005 12.Rangkaew N, Suttisri R, Moriyasu M, Kawanishi K. A new acyclic diterpene acid and bioactive compounds from Knema glauca. Arch Pharm Res. 2009;32(5):685-92. doi:10.1007/s12272- 009-1506-5 13.Akhtar MN, Lam KW, Abas F, Maulidiani, Ahmad S, Shah SAA, et al. New class of acetylcholinesterase inhibitors from the stem bark of Knema laurina and their structural insights. Bioorg Med Chem Lett.2011;21(13):4097-103. doi:10.1016/j.bmcl.2011.04.065 14.Vinayachandra, Chandrashekar KR. Phenolic contents of Knema attenuata fruits and their bioactive potentials. J Herbs Spices Med Plants.2014;20(2):183-95. doi:10.1080/10496475.2013.848390 15.Vinayachandra, Shwetha R, Chandrashekar KR. Larvicidal activities of Knema attenuata (Hook.f. & Thomson) Warb. (Myristicaceae) extracts against Aedes albopictus Skuse and Anopheles stephensi Liston. Parasitol Res. 2011;109(6):1671-6. doi:10.1007/s00436-011-2440-2 16.Joshi BS, Ravindranath KR, Viswanathan N. Structure and stereochemistry of attenuol, a new lignan from Knema attenuata (Wall.) Warb.Experientia. 1978;34(4):422-3. doi:10.1007/bf01935899 17.Gonzalez MJ, Pinto M, Kijjoa A, Anantachoke C, Herz W. Stilbenes and other constituents of Knema austrosiamensis. Phytochemistry.1993;32(2):433-8. doi:10.1016/s0031-9422(00)95010-6 18.Deng JZ, Starck SR, Li S, Hecht SM. Myristinins A and D from Knema elegans, which inhibit DNA polymerase β and cleave DNA. J Nat Prod.2005;68(11):1625-8. doi:10.1021/np058064g 19.Mei Wenli, Ni Wei, Hua Yan, Chen Changxiang. Flavonoids from Knema globularia Natural Product Research and Development. 2002;14(5):26-8. 20.Sriphana U, Yenjai C, Koatthada M. Cytotoxicity of chemical constituents from the roots of Knema globularia. Phytochem Lett.2016;16:129-33. doi:10.1016/j.phytol.2016.03.010 21.Zeng L, Gu ZM, Fang XP, McLaughlin JL. Kneglomeratanol, kneglomeratanones A and B,and related bioactive compounds from Knema glomerata. J Nat Prod. 1994;57(3):376-81.doi:10.1021/np50105a007 22.Alen Y, Nakajima S, Nitoda T, Baba N, Kanzaki H, Kawazu K. Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant. Z Naturforsch C. 2000;55(3-4):300-3. doi:10.1515/znc-2000-3-426 23.Geny C, Riviere G, Bignon J, Birlirakis N, Guittet E, Awang K, et al. Anacardic acids from Knema hookeriana as modulators of Bcl-xL/Bak and Mcl-1/Bid interactions. J Nat Prod.2016;79(4):838-44 doi:10.1021/acs.jnatprod.5b00915 24.Praptiwi, Dewi P, Harapini M. Peroxide value and DPPH (diphenyl picril hydrazilhydrate) free radical scavenger activity of Knema laurina methanol extract. Majalah Farmasi Indonesia. 2006;17(1):32-6. 25.Hake I, Schoenenberger S, Neumann J, Franke K, Paulsen-Merker K, Reymann K, et al. Neuroprotection and enhanced neurogenesis by extract from the tropical plant Knema laurina after inflammatory damage in living brain tissue.J Neuroimmunol. 2009;206(1-2):91-9. doi:10.1016/j.jneuroim.2008.10.007 26.Chinworrungsee M, Wiyakrutta S, Sriubolmas N, Chuailua P, Suksamrarn A. Cytotoxic activities of trichothecenes isolated from an endophytic fungus belonging to order hypocreales. Arch Pharm Res. 2008;31(5):611-6. doi:10.1007/s12272-001-1201-x 27.Ismail N, Akhtar MN, Ismail M, Zareen S, Ali Shah SA, Lajis NH, et al. Neuroprotective effect from stem bark extracts of Knema laurina against H2O2- and Aβ(1-42)-induced cell death in human SH-SY5Y cells. Nat Prod Res.2015;29(16):1571-4. doi:10.1080/14786419.2014.985676 28.Taher M, Susanti D, Rezali MF. A new sesquiterpene from Knema patentinervia. Chem Nat Compd. 2013;48(6):985-7.doi:10.1007/s10600-013-0445-z 29.Ragasa CY, Torres OB, Mandia EH, Bernardo LO, Shen CC. Phenolics from Knema stellata subsp. cryptocaryoides. Chem Nat Compd. 2015;51(6):1169-70. doi:10.1007/s10600-015-1521-3 30.Ravi Kumar K, Ved DK. One hundred red listed medicinal plants of conservation concern in Southern India. Foundation for Revitalization of Local Health Traditions (FRLHT), Bangalore;2000. 31.Wiart C. Medicinal Plants of Asia and the Pacific. 1st ed. Boca Raton: CRC Press; 2006. 32.Burkill IH. A Dictionary of the Economic Products of the Malay Peninsula, Crown Agents for the Colonies. London; 1935.

This material may be protected under Copyright Act which governs the making of photocopies or reproductions of copyrighted materials.
You may use the digitized material for private study, scholarship, or research.

Back to previous page