Genus prismatomeris (Rubiaceae): phytochemistry and their biological activities

Wan Mohd Nuzul Hakimi Wan Salleh

QR Code Link :
Type :	article
Subject :	QH301 Biology
Main Author :	Wan Mohd Nuzul Hakimi Wan Salleh
Additional Authors :	Saidu Jibril Salam Ahmed Abed Nur Athirah Hashim
Title :	Genus prismatomeris (Rubiaceae): phytochemistry and their biological activities

Place of Production :	Tanjong Malim
Publisher :	Fakulti Sains dan Matematik
Year of Publication :	2019
Corporate Name :	Universiti Pendidikan Sultan Idris
PDF Guest :	Click to view PDF file

Abstract : Universiti Pendidikan Sultan Idris

Prismatomeris is a genus of the family Rubiaceae, which is mainly distributed in Southeast Asia. Some of the species were used to treat wounds, hepatitis, anemia, leukocythemia, pneumoconiosis, bronchitis, and as aphrodisiac. Up to now, the reported constituents from the genus Prismatomeris include anthraquinones, iridoids, and triterpenoids. Among them, anthraquinones, the characteristic components of this species become an intention due to their complex structures and significant biological features such as cytotoxic, antitumor, anticancer, antifungal, antimalarial, antiplasmodial, and antituberculosis activities. This review presents a systematic compilation of available data of secondary metabolites and their bioactivity studies of the genus Prismatomeris. It may lead to upcoming drug design, and therefore, provide a reference for advanced study and application of Prismatomeris.

References

1. Lemmens RH, Bunyapraphatsara N. Plant Resources of South-East Asia, Medicinal and Poisonous Plants. Bogor, Indonesia: Prosea Foundation; 2003.

2. Ridley HN. The Flora of the Malay Peninsula. Kuala Lumpur: L. Reeve and Co., Ltd; 1967.

3. Johansson JT. Revision of the genus perismatomeris thw. (Rubiaceae, morindeae). Opera Bot 1987;94:5.

4. Smitinand T. Thai Plant Names Revised Edition 2014. Bangkok: Prachachon Co., Ltd; 2001.

5. Likhitwitayawuid K, Dej-Adisa S, Jongbunprasert V, Krunfkrai J. Antimalarials from stephania Venosa, Prismatomeris sessiliflora, Diospyros Montana and Murraya siamensis. Planta Med 1999;65:754-6.

6. Feng ZM, Jiang JS, Wang YH, Zhang PC. Anthraquinones from the roots of Prismatomeris tetrandra. Chem Pharm Bull 2005;53:1330-2.

7. Feng SX, Hao J, Chen T, Qiu SX. A new anthraquinone and two new tetrahydroanthraquinones from the roots of Prismatomeris connata. Helvet Chim Acta 2011;94:1843-9.

8. Feng SX, Zhang M, Xu J, Hu Y. Prisconnatanones A, a cytotoxic naphthoquinone from Prismatomeris connata, suppresses the proliferation of humanaryngocarcinoma hep-2 cells in vitro. Nat Prod Res 2016;30:2840-4.

9. Tuntiwachwuttikul P, Butsuri Y, Sukkoet P, Prawat U, Taylor WC. Anthraquinones from the roots of Prismatomeris malayana. Nat Prod Res 2008;22:962-8.

10. Zhang CL, Guan H, Xi PZ, Deng T, Gao JM. Anthraquinones from the roots of Prismatomeris tetrandra. Nat Prod Commun 2010;5:1251-2.

11. Mohamad TA, Naza H, Jalal RS, Hussin K, Rahman MR, Adam A, et al. Chemical and pharmacognostical characterization of two Malaysian plants both known as Ajisamat. Rev Braz Farmacogn 2013;23:724-30.

12. Wang C, Ding X, Feng SX, Guan Q, Zhang XP, Du C, et al. Seven new tetrahydroanthraquinones from the root of Prismatomeris connata and their cytotoxicity against lung tumor cell growth. Molecules 2015;20:22565-77.

13. Hao J, Feng SX, Qiu SX, Chen T. Anthraquinone glycosides from the roots of Prismatomeris connata. Chin J Nat Med 2011;9:42-45.

14. Krohn K, Gehle D, Dey SK, Nahar N, Mosihuzzaman M, Sultana N, et al. Prismatomerin, a new iridoid from Prismatomeris tetrandra. Structure elucidation, determination of absolute configuration, and cytotoxicity. J Nat Prod 2007;70:1339-43.

15. Kanokmedhakul K, Kanokmedhakul S, Phatchana R. Biological activity of anthraquinones and triterpenoids from Prismatomeris fragrans. J Ethnopharmacol 2005;100:284-8.

16. Burkill IH. Dictionary of the Economic Products of the Malay Peninsula. Vol. 2. London Crown Agents; 1935.

17. Ruan YZ. Notes on the genus prismatomeris Thw. (Rubiaceae) of China. J Syst Evol 1988;26:443-9.

18. Feng SX, Bai J, Qiu SX, Li Y, Chen T. Iridoid and phenolic glycosides from the roots of Prismatomeris connata. Nat Prod Commun 2012;7:561-2.

19. Salleh RM, Hasan MH, Adam A. Phenolic compound and antioxidant levels of Prismatomeris glabra. J Pharmacogn Phytochem 2015;3:5-11.

20. Tu D, Pang Z, Bi N. Sudies on chemical constituents of Prismatomeris tetrandra (Roxb) K Schum. Yao Xue Xue Bao 1981;16:631-4.

21. Dey SK, Islam S, Mostafa M, Nahar N, Mosihuzzaman M. Some secondary metabolites from cytotoxic extract of Prismatomeris tetrandra. J Bangl Chem Soc 2003;16:22-7.

22. Jiang J, Feng Z, Zhang P. Chemical constituents from root of Prismatomeris tetrandra. Zhongguo Zhong Yao Za Zhi 2005;30:1751-3.

23. Zhou CY, Deng JG. Progress in chemical and pharmacological studies on Prismatomeris tetrandra. Guangxi Tradit Chin Med Univ J 2006;9:90-2.

24. Lee HH. Colouring matters from Prismatomeris malayana. Phytochemistry 1969;8:501.

25. Abdullah NH. Chemical Constituents of Prismatomeris Malayana Ridley and Quantitative Structure Activity Relationship Study on Anti-Inflammatory agents and their analogues. PhD Thesis, Department Of Chemistry, Faculty of Science, Kuala Lumpur: Universiti of Malaya; 2014.

26. Abdullah NH, Thomas NF, Sivasothy Y, Lee VS, Liew SY, Noorbatcha IA, et al. Hyaluronidase inhibitory activity of pentacylic triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, synthesis and QSAR study. Int J Mol Sci 2016;17:143.

27. Azmi N, Loh WT, Omar SS, Jalil J, Adam A. Effects of aqueous extract of Prismatomeris glabra root on nonspatial memory in rats using object discrimination test. Sains Malays 2011;40:1097-103.

This material may be protected under Copyright Act which governs the making of photocopies or reproductions of copyrighted materials.
You may use the digitized material for private study, scholarship, or research.

Back to previous page