Chemical composition and biological activities of Dipterocarpus cornutus dyer essential oil

Wan Mohd Nuzul Hakimi Wan Salleh

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Type :	article
Subject :	QH301 Biology
Main Author :	Wan Mohd Nuzul Hakimi Wan Salleh
Additional Authors :	Shamsul Khamis Muhammad Nurakmal Abdul Rahman Mohd azlan Nafiah
Title :	Chemical composition and biological activities of Dipterocarpus cornutus dyer essential oil

Place of Production :	Tanjong Malim
Publisher :	Fakulti Sains dan Matematik
Year of Publication :	2020
Corporate Name :	Universiti Pendidikan Sultan Idris

Abstract : Universiti Pendidikan Sultan Idris

The design of this study was developed to examine the chemical composition, anticholinesterase and anti-inflammatory inhibitory activities of the essential oil of Dipterocarpus cornutus Dyer from Malaysia. Gas chromatography (GC) and gas chromatography/mass spectrometry (GC-MS) analysis of the essential oil revealed 20 components, representing 94.6% of the oil. The major components identified were α-gurjunene (50.6%), α-selinene (8.3%), spathulenol (5.7%), and bicyclogerma-crene (5.4%). Anticholinesterase and anti-inflammatory activity were also evaluated using the Ellman method and lipoxygenase (LOX) enzyme, respectively, in which the essential oil revealed weak inhibitory activity against the acetylcholinesterase (AChE) (I%: 30.2%) and butyrylcho-linesterase (BChE) (I%: 32.5%), while moderate inhibitory activity was reported in the LOX (I%: 70.2%). The approach adopted in this study and results are reported for the first time which could be useful for the characterization, pharmaceutical and therapeutic applications of the essential oil from Dipterocarpus genus.

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