UPSI Digital Repository (UDRep)
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Abstract : Universiti Pendidikan Sultan Idris |
This study aimed to develop a voltammetric sensor for the determination of bisphenol
A (BPA), uric acid (UA), dopamine (DA) and acetaminophen (ACT) using multiwalled
carbon nanotubes incorporated with zinc/aluminium layered double hydroxidequinmerac
(Sensor 1), zinc/aluminium layered double hydroxide-quinclorac (Sensor 2)
and zinc/aluminium layered double hydroxide-clopyralid (Sensor 3). The surface
morphological was determined using field emission scanning electron microscope. The
electrochemical properties were characterized by cyclic voltammetry, square wave
voltammetry and electrochemical impedance spectroscopy. Several experimental
variables of voltammetric analysis such as composition ratios, type of supporting
electrolyte, pH of the solution and square wave voltammetry parameters were
optimized. The effective surface area of electrodes was determined by
chronocoulometry. At the optimum conditions, Sensor 1 showed three linear ranges for
the single determination of BPA (30 to 700 nM, 1 to 10 μM and 30 to 300 μM) with
detection limit of 4.4 nM. Sensor 2 showed simultaneous determination of UA and
BPA. The linear ranges for UA is from 0.3 to 30 μM and 50 to 100 μM while for BPA
is from 0.3 to 5 μM and 10 to 100 μM with detection limit are 0.065 μM and 0.049 μM,
respectively. Sensor 3 showed simultaneous determination of DA, ACT and BPA with
linear ranges from 7 to 500 μM, 30 to 500 μM and 3 to 500 μM and with detection limit
of 0.172 μM, 0.179 μM and 0.136 μM, respectively. All the developed sensors did not
interfere by several foreign ions. In a conclusion, the proposed electrodes exhibited
good analytical performance with excellent sensitivity and selectivity. In its
implication, these fabricated electrodes are applicable for determination of BPA, UA,
ACT and DA in baby bottle, baby teether, water samples, urine and pharmaceutical
tablets. |
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