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Type :thesis
Subject :QE Geology
Main Author :Nurashikin Abd Azis
Title :Voltammetric sensors of bisphenol A, uric acid, dopamine and acetaminophen using layered double hydroxide modified multiwalled carbon nanotubes paste
Place of Production :Tanjong Malim
Publisher :Fakulti Sains dan Matematik
Year of Publication :2021
Corporate Name :Universiti Pendidikan Sultan Idris
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Abstract : Universiti Pendidikan Sultan Idris
This study aimed to develop a voltammetric sensor for the determination of bisphenol A (BPA), uric acid (UA), dopamine (DA) and acetaminophen (ACT) using multiwalled carbon nanotubes incorporated with zinc/aluminium layered double hydroxidequinmerac (Sensor 1), zinc/aluminium layered double hydroxide-quinclorac (Sensor 2) and zinc/aluminium layered double hydroxide-clopyralid (Sensor 3). The surface morphological was determined using field emission scanning electron microscope. The electrochemical properties were characterized by cyclic voltammetry, square wave voltammetry and electrochemical impedance spectroscopy. Several experimental variables of voltammetric analysis such as composition ratios, type of supporting electrolyte, pH of the solution and square wave voltammetry parameters were optimized. The effective surface area of electrodes was determined by chronocoulometry. At the optimum conditions, Sensor 1 showed three linear ranges for the single determination of BPA (30 to 700 nM, 1 to 10 μM and 30 to 300 μM) with detection limit of 4.4 nM. Sensor 2 showed simultaneous determination of UA and BPA. The linear ranges for UA is from 0.3 to 30 μM and 50 to 100 μM while for BPA is from 0.3 to 5 μM and 10 to 100 μM with detection limit are 0.065 μM and 0.049 μM, respectively. Sensor 3 showed simultaneous determination of DA, ACT and BPA with linear ranges from 7 to 500 μM, 30 to 500 μM and 3 to 500 μM and with detection limit of 0.172 μM, 0.179 μM and 0.136 μM, respectively. All the developed sensors did not interfere by several foreign ions. In a conclusion, the proposed electrodes exhibited good analytical performance with excellent sensitivity and selectivity. In its implication, these fabricated electrodes are applicable for determination of BPA, UA, ACT and DA in baby bottle, baby teether, water samples, urine and pharmaceutical tablets.

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