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Type :article
Subject :Q Science
ISSN :0939-5075
Main Author :Muhammad Taher
Additional Authors :Wan Mohd Nuzul Hakimi Wan Salleh
Title :A new xanthone dimer and cytotoxicity from the stem bark of Calophyllum canum
Place of Production :Tanjung Malim
Publisher :Fakulti Sains dan Matematik
Year of Publication :2021
Notes :Zeitschrift fur Naturforschung - Section C Journal of Biosciences
Corporate Name :Universiti Pendidikan Sultan Idris
Web Link :Click to view web link

Abstract : Universiti Pendidikan Sultan Idris
A phytochemical investigation of the stem bark of Calophyllum canum resulted in the isolation of a new xanthone dimer identified as biscaloxanthone (1), together with four compounds; trapezifoliaxanthone (2), trapezifolixanthone A (3), taraxerone (4) and taraxerol (5). The structures of these compounds were determined via spectroscopic methods of IR, UV, MS and NMR (1D and 2D). The cytotoxicity of compounds 1-3 were screened against A549, MCF-7, C33A and 3T3L1 cell lines, wherein weak cytotoxic activities were observed (IC50 > 50 ?m). 2020 Walter de Gruyter GmbH, Berlin/Boston 2020.

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