|
UPSI Digital Repository (UDRep)
|
|
| ||||||||||||||||||||||||||
| Abstract : Universiti Pendidikan Sultan Idris |
| The existing study examined three actinomycetes isolated from Beach Ridges Interspersed with Swales (BRIS) soil where the morphological properties were examined and chemical compounds of their metabolite extracts were ana; ysed. Based on phylogenetic analysis of 16S rRNA gene sequences, the strains were identified as Streptomyces sp. AA13, Amycolatopsis sp. AA12 and Micromonosporasp. AA141. Antimicrobial activities of the extracts were tested against a panel of microorganisms that consist of Escherichia coli DSM 30083, Bacillus subtilis DSM 10, Pseudomonas fluorescens DSM 50090, Klebsiella pneumoniae DSM 30104, Micrococcus luteus DSM 20030, and Saccharomyces cerevisiae. Results revealed a wide range of antimicrobial activities produced by the isolates at different concentration of each extracts. The extracts were found to show stronger antimicrobial activities against gram-negative bacteria compared to gram-positive bacteria, while no activities were shown when tested against fungi. Thirty-nine compounds were detected both from Streptomycessp. AA13 and Amycolatopsissp. AA12, while thirty-eight compounds from Micromonosporasp. AA141 using GC-MS. This Study Demonstrate the ability of actinomycetes in producing variety type of compounds with antimicrobial activities that may be the potential candidates as drug leads. ? RJPT All right reserved. |
| References |
Actinomycetes: Still a source of novel antibiotics. (2017). Natural Product Reports, 34(10), 1203-1232. doi:10.1039/c7np00026j Diastuti, H., Asnani, A., Rastuti, U., & Anggraeni, M. (2020). Toxicity of benzyl benzoate from kaempferia rotunda L. rhizome. Paper presented at the AIP Conference Proceedings, , 2237 doi:10.1063/5.0005554 Retrieved from www.scopus.com Eberhardt, M. J. (2017). Síntese De Iodeto De N-(2, 3-Dimetil-6-Benzotiazolio) Decanamida E Incorporação Em Niossomas Visando Potencial Aplicação Antibacterian, 21(6), 452-476. Retrieved from www.scopus.com Faja, O., Sharad, A., Younis, K. M., Usup, G., & Ahmad, A. J. I. J. C. R. (2017). Isolation, screening and antibiotic profiling of marine actinomycetes extracts from the coastal of peninsular malaysia. Int J Chemtech Res, 10(3), 212-224. Retrieved from www.scopus.com Hodaj, E., Tsiftsoglou, O., Abazi, S., Hadjipavlou-Litina, D., & Lazari, D. (2017). Lignans and indole alkaloids from the seeds of centaurea vlachorum hartvig (asteraceae), growing wild in albania and their biological activity. Natural Product Research, 31(10), 1195-1200. doi:10.1080/14786419.2016.1226823 Huang, Z. -., Lin, Y. -., & Fang, J. -. (2009). Biological and pharmacological activities of squalene and related compounds: Potential uses in cosmetic dermatology. Molecules, 14(1), 540-554. doi:10.3390/molecules14010540 Idris, H., Labeda, D. P., Nouioui, I., Castro, J. F., del Carmen Montero-Calasanz, M., Bull, A. T., . . . Goodfellow, M. (2017). Streptomyces aridus sp. nov., isolated from a high altitude atacama desert soil and emended description of streptomyces noboritoensis isono et al. 1957. Antonie Van Leeuwenhoek, International Journal of General and Molecular Microbiology, 110(5), 705-717. doi:10.1007/s10482-017-0838-2 Idris, H., Nouioui, I., Asenjo, J. A., Bull, A. T., & Goodfellow, M. (2017). Lentzea chajnantorensis sp. nov., an actinobacterium from a very high altitude cerro chajnantor gravel soil in northern chile. Antonie Van Leeuwenhoek, International Journal of General and Molecular Microbiology, 110(6), 795-802. doi:10.1007/s10482-017-0851-5 Idris, H., Nouioui, I., Pathom-aree, W., Castro, J. F., Bull, A. T., Andrews, B. A., . . . Goodfellow, M. (2018). Amycolatopsis vastitatis sp. nov., an isolate from a high altitude subsurface soil on cerro chajnantor, northern chile. Antonie Van Leeuwenhoek, International Journal of General and Molecular Microbiology, 111(9), 1523-1533. doi:10.1007/s10482-018-1039-3 Jacoby, R., Peukert, M., Succurro, A., Koprivova, A., & Kopriva, S. (2017). The role of soil microorganisms in plant mineral nutrition—current knowledge and future directions. Frontiers in Plant Science, 8 doi:10.3389/fpls.2017.01617 Jegan, S., Raj, G. A., Chandrasekaran, M., & Venkatesalu, V. (2019). Anti-MRSA activity of padina tetrastromatica,padina gymnospora from gulf of mannar biosphere. World Sci.News, 115, 15-26. Retrieved from www.scopus.com Kavitha, R., & Uduman, M. A. M. (2017). Identification of bioactive components and its biological activities of abelmoschas moschatus flower extrtact-A gc-ms study. IOSR J Appl Chem, 10(11), 19-22. Retrieved from www.scopus.com Kornman, K. S., & Loesche, W. J. (1978). New medium for isolation of actinomyces viscosus and actinomyces naeslundii from dental plaque. Journal of Clinical Microbiology, 7(6), 514-518. Retrieved from www.scopus.com Marahatta, A. B., Poudel, B., & Basnyat, R. C. (2019). The phytochemical and nutritional analysis and biological activity of tectaria coadunate linn. International Journal of Herbal Medicine, 7, 42-50. Retrieved from www.scopus.com Maroyi, A. (2019). The therapeutic potential of notobubon galbanum: A review of its medicinal uses and phytochemistry. Journal of Pharmaceutical Sciences and Research, 11(11), 3661-3665. Retrieved from www.scopus.com Mohammad, H., Prabhu, K., Rao, M. R. K., Sundaram, R. L., Shil, S., & Vijayalakshmi, N. (2019). The GC MS studies of one ayurvedic medicine, amritarishtam. Research Journal of Pharmacy and Technology, 12(1), 351-356. doi:10.5958/0974-360X.2019.00064.7 Oladimeji, H. O., Attih, E. E., & Onu, O. N. (2017). Ethyl linalool and diethyl phthalate from pycnanthus angolensis (welw.) warb. Eur.Chem.Bull., 6(2), 76-78. Retrieved from www.scopus.com Rassem, A. M., David, A. A., & Thomas, T. (2018). Phylogenetic analysis of actinomysetes isolated from rhizospher of pisum sativum L. Journal of Pharmacognosy and Phytochemistry, 7(2), 766-770. Retrieved from www.scopus.com Rodríguez, C., Álvarez, F., Pérez, L., & Galarza, C. (2018). PRODUCTION of ANTIFUNGAL COMPOUNDS by ACTINOMYCETES ISOLATED from ANDEAN and ANTARCTIC SOILS. Italian Journal of Food Science, 30(5), 151-163. doi:10.14674/IJFS-1614 Salat, K., Librowski, T., Moniczewski, A., Stanisz-Wallis, K., Wieckowski, K., & Malawska, B. (2012). Analgesic, antioedematous and antioxidant activity of γ-butyrolactone derivatives in rodents. Behavioural Pharmacology, 23(4), 407-416. doi:10.1097/FBP.0b013e3283566042 Salleh, W. M. N. H. W., & Ahmad, F. (2017). Phytochemistry and biological activities of the genus ocotea (lauraceae): A review on recent research results (2000-2016). Journal of Applied Pharmaceutical Science, 7(5), 204-218. doi:10.7324/JAPS.2017.70534 Salleh, W. M. N. H. W., Hashim, N. A., Fabarani, N. P., & Ahmad, F. (2020). Antibacterial activity of constituents from piper retrofractum vahl. and piper arborescens roxb. Agriculturae Conspectus Scientificus, 85(3), 269-280. Retrieved from www.scopus.com Shah, A. M., Shakeel-u-Rehman, Hussain, A., Mushtaq, S., Rather, M. A., Shah, A., . . . Hassan, Q. P. (2017). Antimicrobial investigation of selected soil actinomycetes isolated from unexplored regions of kashmir himalayas, india. Microbial Pathogenesis, 110, 93-99. doi:10.1016/j.micpath.2017.06.017 Shirling, E. B., & Gottlieb, D. (1966). Methods for characterization of streptomyces species. Int.J.Syst.Bacteriol., 16, 313-340. Retrieved from www.scopus.com Subramani, R., & Sipkema, D. (2019). Marine rare actinomycetes: A promising source of structurally diverse and unique novel natural products. Marine Drugs, 17(5) doi:10.3390/md17050249 Takahashi, Y., & Nakashima, T. (2018). Actinomycetes, an inexhaustible source of naturally occurring antibiotics. Antibiotics, 7(2) doi:10.3390/antibiotics7020045 Wang, L., Qiu, P., Long, X. -., Zhang, S., Zeng, Z. -., & Tian, Y. -. (2016). Comparative analysis of chemical constituents, antimicrobial and antioxidant activities of ethylacetate extracts of polygonum cuspidatum and its endophytic actinomycete, streptomyces sp. A0916. Chinese Journal of Natural Medicines, 14(2), 117-123. doi:10.1016/S1875-5364(16)60004-3 Wang, T., Liu, Y. -., Wang, X., Yang, N., Zhu, H. -., & Zuo, P. -. (2010). Protective effects of octacosanol on 6-hydroxydopamine-induced parkinsonism in rats via regulation of ProNGF and NGF signaling. Acta Pharmacologica Sinica, 31(7), 765-774. doi:10.1038/aps.2010.69 Wichner, D., Idris, H., Houssen, W. E., McEwan, A. R., Bull, A. T., Asenjo, J. A., . . . Rateb, M. E. (2017). Isolation and anti-HIV-1 integrase activity of lentzeosides A-F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude atacama desert soil. Journal of Antibiotics, 70(4), 448-453. doi:10.1038/ja.2016.78 Zhang, S., Zu, Y. -., Fu, Y. -., Luo, M., Zhang, D. -., & Efferth, T. (2010). Rapid microwave-assisted transesterification of yellow horn oil to biodiesel using a heteropolyacid solid catalyst. Bioresource Technology, 101(3), 931-936. doi:10.1016/j.biortech.2009.08.069 |
| This material may be protected under Copyright Act which governs the making of photocopies or reproductions of copyrighted materials. You may use the digitized material for private study, scholarship, or research. |