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Type :article
Subject :QD Chemistry
ISSN :1478-6419
Main Author :Wan Mohd Nuzul Hakimi Wan Salleh
Additional Authors :Muhammad Zul Afiq Anuar
Mohd Azlan Nafiah
Title :Chemical investigation and biological activities of the essential oil of Knema kunstleri Warb. from Malaysia
Place of Production :Tanjung Malim
Publisher :Fakulti Sains dan Matematik
Year of Publication :2021
Notes :Natural Product Research
Corporate Name :Universiti Pendidikan Sultan Idris
Web Link :Click to view web link
PDF Full Text :Login required to access this item.

Abstract : Universiti Pendidikan Sultan Idris
The chemical composition of the essential oil of Knema kunstleri Warb. (Myristicaceae) was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterized by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). In total, 36 components were identified in the essential oil, which made up 91.7% of the total oil. The essential oil is composed mainly of ?-caryophyllene (23.2%), bicyclogermacrene (9.6%), ?-cadinene (7.3%), ?-humulene (5.7%), and germacrene D (4.3%). The essential oil showed moderate activity towards DPPH free-radical scavenging and lipoxygenase inhibition. To the best of our knowledge, this is the first study of the composition and bioactivities of the essential oil report concerning the genus Knema. ? 2019 Informa UK Limited, trading as Taylor & Francis Group.

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