UPSI Digital Repository (UDRep)
Start | FAQ | About

QR Code Link :

Type :article
Subject :Q Science (General)
ISSN :2046-2069
Main Author :Maizatul Najwa Jajuli
Title :Graphene and zeolite as adsorbents in bar-micro-solid phase extraction of pharmaceutical compounds of diverse polarities
Place of Production :Tanjung Malim
Publisher :Fakulti Sains dan Matematik
Year of Publication :2021
Notes :RSC Advances
Corporate Name :Universiti Pendidikan Sultan Idris
HTTP Link :Click to view web link

Abstract : Universiti Pendidikan Sultan Idris
A bar micro-solid phase (bar ?-SPE) extraction method using either graphene or zeolite or their mixtures as an adsorbent, coupled with high-performance liquid chromatography (using a C1 column) was developed for the simultaneous determination of pharmaceutical compounds (metformin (MET), buformin (BUF), phenformin (PHEN) and propranolol (PROP)) of diverse polarity (log?P from -1.82 to 3.10). Parameters influencing the extraction, such as conditioning solvents, pH of the sample, sample volume, amount of adsorbent, stirring rate, time of extraction, type and volume of desorption solvent and time of desorption were investigated. Under the optimized conditions, the extraction method using graphene (extraction efficiency, % EE, ?6-15%) resulted in the least amount of extracted drugs. However, the use of zeolite and zeolite/graphene mixtures improves the % EE significantly, i.e. 30% for PHEN and 42% for PROP using zeolite; 22% for MET and 18% for BUF using the adsorbent mixture. Under similar conditions, enrichment factors for these drugs range from 11-15. The validated method was performed for the determination of the drugs that were spiked to urine samples. Good recoveries ranging from 72.8 to 116% were achieved. This journal is ? The Royal Society of Chemistry.

References

Abdullah AlFaris, N., Zaidan ALTamimi, J., ALOthman, Z. A., Fahad Al Qahtani, S., Wabaidur, S. M., Ghfar, A. A., & Saleh Aldayel, T. (2020). Analysis of aflatoxins in foods retailed in saudi arabia using immunoaffinity column cleanup and high-performance liquid chromatography-fluorescence detection. Journal of King Saud University - Science, 32(2), 1437-1443. doi:10.1016/j.jksus.2019.11.039

Abdullah AlFaris, N., Zaidan ALTamimi, J., ALOthman, Z. A., Wabaidur, S. M., Ghafar, A. A., & Saleh Aldayel, T. (2020). Development of a sensitive liquid-liquid extraction and ultra-performance liquid chromatography-tandem mass spectrometry method for the analysis of carbaryl residues in fresh vegetables sold in riyadh. Journal of King Saud University - Science, 32(4), 2414-2418. doi:10.1016/j.jksus.2020.03.030

AbuRuz, S., Millership, J., & McElnay, J. (2003). Determination of metformin in plasma using a new ion pair solid phase extraction technique and ion pair liquid chromatography. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 798(2), 203-209. doi:10.1016/j.jchromb.2003.09.043

Adlnasab, L., Ezoddin, M., Shojaei, R. A., & Aryanasab, F. (2018). Ultrasonic-assisted dispersive micro solid-phase extraction based on melamine-phytate supermolecular aggregate as a novel bio-inspired magnetic sorbent for preconcentration of anticancer drugs in biological samples prior to HPLC-UV analysis. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1095, 226-234. doi:10.1016/j.jchromb.2018.08.001

AlFaris, N. A., Wabaidur, S. M., Alothman, Z. A., Altamimi, J. Z., & Aldayel, T. S. (2020). Fast and efficient immunoaffinity column cleanup and liquid chromatography–tandem mass spectrometry method for the quantitative analysis of aflatoxins in baby food and feeds. Journal of Separation Science, 43(11), 2079-2087. doi:10.1002/jssc.201901307

Almasoud, N., Wabaidur, S. M., Alothman, Z. A., Ghfar, A. A., & Alomar, T. S. (2020). A solid phase extraction based uplc-esi-ms/ms method using surfactant-modified clay as extraction sorbent for the removal andetermination of rhodamine b in industrial wastewater samples. Desalination and Water Treatment, 195, 222-231. doi:10.5004/dwt.2020.25896

ALOthman, Z. A., Habila, M. A., Yilmaz, E., Alabdullkarem, E. A., & Soylak, M. (2020). A novel deep eutectic solvent microextraction procedure for enrichment, separation and atomic absorption spectrometric determination of palladium at ultra-trace levels in environmental samples. Measurement: Journal of the International Measurement Confederation, 153 doi:10.1016/j.measurement.2019.107394

ALOthman, Z. A., & Wabaidur, S. M. (2019). Application of carbon nanotubes in extraction and chromatographic analysis: A review. Arabian Journal of Chemistry, 12(5), 633-651. doi:10.1016/j.arabjc.2018.05.012

Alshishani, A., Makahleh, A., Yap, H. F., Gubartallah, E. A., Salhimi, S. M., & Saad, B. (2016). Ion-pair vortex assisted liquid-liquid microextraction with back extraction coupled with high performance liquid chromatography-UV for the determination of metformin in plasma. Talanta, 161, 398-404. doi:10.1016/j.talanta.2016.08.067

Alshishani, A., Saaid, M., Basheer, C., & Saad, B. (2019). High performance liquid chromatographic determination of triclosan, triclocarban and methyl-triclosan in wastewater using mini-bar micro-solid phase extraction. Microchemical Journal, 147, 339-348. doi:10.1016/j.microc.2019.03.044

Andrade-Eiroa, A., Canle, M., Leroy-Cancellieri, V., & Cerdà, V. (2016). Solid-phase extraction of organic compounds: A critical review. part ii. TrAC - Trends in Analytical Chemistry, 80, 655-667. doi:10.1016/j.trac.2015.08.014

Asadi, S., & Nojavan, S. (2016). Two-step voltage dual electromembrane extraction: A new approach to simultaneous extraction of acidic and basic drugs. Analytica Chimica Acta, 923, 24-32. doi:10.1016/j.aca.2016.04.007

Asl, Y. A., Yamini, Y., Seidi, S., & Rezazadeh, M. (2016). Simultaneous extraction of acidic and basic drugs via on-chip electromembrane extraction. Analytica Chimica Acta, 937, 61-68. doi:10.1016/j.aca.2016.07.048

Azhar, A., Yamauchi, Y., Allah, A. E., Alothman, Z. A., Badjah, A. Y., Naushad, M., . . . Zakaria, M. B. (2019). Nanomaterials, 9, 1-11. Retrieved from www.scopus.com

Basheer, C., Ali Alnedhary, A., Rao, B. S. M., Valliyaveettil, S., & Lee, H. K. (2006). Development and application of porous membrane-protected carbon nanotube micro-solid-phase extraction combined with gas chromatography/mass spectrometry. Analytical Chemistry, 78(8), 2853-2858. doi:10.1021/ac060240i

Basheer, C., Lee, J., Pedersen-Bjergaard, S., Rasmussen, K. E., & Lee, H. K. (2010). Simultaneous extraction of acidic and basic drugs at neutral sample pH: A novel electro-mediated microextraction approach. Journal of Chromatography A, 1217(43), 6661-6667. doi:10.1016/j.chroma.2010.04.066

Bavatharani, C., Muthusankar, E., Alothman, Z. A., Wabaidur, S. M., Ponnusamy, V. K., & Ragupathy, D. (2020). Ultra-high sensitive, selective, non-enzymatic dopamine sensor based on electrochemically active graphene decorated polydiphenylamine-SiO2 nanohybrid composite. Ceramics International, 46(14), 23276-23281. doi:10.1016/j.ceramint.2020.06.054

Beausse, J. (2004). Selected drugs in solid matrices: A review of environmental determination, occurrence and properties of principal substances. TrAC - Trends in Analytical Chemistry, 23(10-11), 753-761. doi:10.1016/j.trac.2004.08.005

Berduque, A., Sherburn, A., Ghita, M., Dryfe, R. A. W., & Arrigan, D. W. M. (2005). Electrochemically modulated liquid-liquid extraction of ions. Analytical Chemistry, 77(22), 7310-7318. doi:10.1021/ac051029u

Brittain, H. G. (2007). Profiles of drug substances, excipients and related methodology. Profiles of Drug Substances, Excipients and Related Methodology, Retrieved from www.scopus.com

Domínguez-Romero, J. C., García-Reyes, J. F., & Molina-Díaz, A. (2014). Comparative evaluation of seven different sample treatment approaches for large-scale multiclass sport drug testing in urine by liquid chromatography-mass spectrometry. Journal of Chromatography A, 1361, 34-42. doi:10.1016/j.chroma.2014.07.090

Fan, W., He, M., You, L., Zhu, X., Chen, B., & Hu, B. (2016). Water-compatible graphene oxide/molecularly imprinted polymer coated stir bar sorptive extraction of propranolol from urine samples followed by high performance liquid chromatography-ultraviolet detection. Journal of Chromatography A, 1443, 1-9. doi:10.1016/j.chroma.2016.03.017

Fernández, E., Vidal, L., & Canals, A. (2016). Zeolite/iron oxide composite as sorbent for magnetic solid-phase extraction of benzene, toluene, ethylbenzene and xylenes from water samples prior to gas chromatography⬜mass spectrometry. Journal of Chromatography A, 1458, 18-24. doi:10.1016/j.chroma.2016.06.049

Gabr, R. Q., Padwal, R. S., & Brocks, D. R. (2010). Determination of metformin in human plasma and urine by high-performance liquid chromatography using small sample volume and conventional octadecyl silane column. Journal of Pharmacy and Pharmaceutical Sciences, 13(4), 486-494. doi:10.18433/j32c71

Habila, M. A., Alothman, Z. A., Yilmaz, E., & Soylak, M. (2018). Activated carbon cloth filled pipette tip for solid phase extraction of nickel(II), lead(II), cadmium(II), copper(II) and cobalt(II) as 1,3,4-thiadiazole-2,5-dithiol chelates for ultra-trace detection by FAAS. International Journal of Environmental Analytical Chemistry, 98(2), 171-181. doi:10.1080/03067319.2018.1430794

Habila, M. A., Alothman, Z. A., Yilmaz, E., & Soylak, M. (2018). Dispersive liquid-liquid microextraction of lead(II) as tropaeolin ooo chelates from environmental samples prior to microsampling flame atomic absorption spectrometry. Atomic Spectroscopy, 39(3), 112-117. Retrieved from www.scopus.com

Hanson, K. B., Hoff, D. J., Lahren, T. J., Mount, D. R., Squillace, A. J., & Burkhard, L. P. (2019). Estimating n-octanol-water partition coefficients for neutral highly hydrophobic chemicals using measured n-butanol-water partition coefficients. Chemosphere, 218, 616-623. doi:10.1016/j.chemosphere.2018.11.141

Hemmati, M., Rajabi, M., & Asghari, A. (2017). Ultrasound-promoted dispersive micro solid-phase extraction of trace anti-hypertensive drugs from biological matrices using a sonochemically synthesized conductive polymer nanocomposite. Ultrasonics Sonochemistry, 39, 12-24. doi:10.1016/j.ultsonch.2017.03.024

Huo, F., Tang, H., Wu, X., Chen, D., Zhao, T., Liu, P., & Li, L. (2016). Utilizing a novel sorbent in the solid phase extraction for simultaneous determination of 15 pesticide residues in green tea by GC/MS. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1023-1024, 44-54. doi:10.1016/j.jchromb.2016.04.053

Jajuli, M. N., Hussin, M. H., Saad, B., Rahim, A. A., Hébrant, M., & Herzog, G. (2019). Electrochemically modulated liquid-liquid extraction for sample enrichment. Analytical Chemistry, 91(11), 7466-7473. doi:10.1021/acs.analchem.9b01674

Kanimozhi, S., Basheer, C., Narasimhan, K., Liu, L., Koh, S., Xue, F., . . . Lee, H. K. (2011). Application of porous membrane protected micro-solid-phase-extraction combined with gas chromatography-mass spectrometry for the determination of estrogens in ovarian cyst fluid samples. Analytica Chimica Acta, 687(1), 56-60. doi:10.1016/j.aca.2010.12.007

Koruni, M. H., Tabani, H., Gharari, H., & Fakhari, A. R. (2014). An all-in-one electro-membrane extraction: Development of an electro-membrane extraction method for the simultaneous extraction of acidic and basic drugs with a wide range of polarities. Journal of Chromatography A, 1361, 95-99. doi:10.1016/j.chroma.2014.07.075

Lai, E. P. C., & Feng, S. Y. (2006). Solid phase extraction-non-aqueous capillary electrophoresis for determination of metformin, phenformin and glyburide in human plasma. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 843(1), 94-99. doi:10.1016/j.jchromb.2006.05.030

Langmaier, J., Pižl, M., Samec, Z., & Záliš, S. (2016). Extreme basicity of biguanide drugs in aqueous solutions: Ion transfer voltammetry and DFT calculations. Journal of Physical Chemistry A, 120(37), 7344-7350. doi:10.1021/acs.jpca.6b04786

Lee, T. P., Saad, B., Ng, E. P., & Salleh, B. (2012). Zeolite linde type L as micro-solid phase extraction sorbent for the high performance liquid chromatography determination of ochratoxin A in coffee and cereal. Journal of Chromatography A, 1237, 46-54. doi:10.1016/j.chroma.2012.03.031

Lin, S., Yang, X., & Liu, H. (2019). Development of liposome/water partition coefficients predictive models for neutral and ionogenic organic chemicals. Ecotoxicology and Environmental Safety, 179, 40-49. doi:10.1016/j.ecoenv.2019.04.036

Luo, X., Zhang, F., Ji, S., Yang, B., & Liang, X. (2014). Graphene nanoplatelets as a highly efficient solid-phase extraction sorbent for determination of phthalate esters in aqueous solution. Talanta, 120, 71-75. doi:10.1016/j.talanta.2013.11.079

Luo, Y. -., Yuan, B. -., Yu, Q. -., & Feng, Y. -. (2012). Substrateless graphene fiber: A sorbent for solid-phase microextraction. Journal of Chromatography A, 1268, 9-15. doi:10.1016/j.chroma.2012.10.035

Magiera, S., Hejniak, J., & Baranowski, J. (2014). Comparison of different sorbent materials for solid-phase extraction of selected drugs in human urine analyzed by UHPLC-UV. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 958, 22-28. doi:10.1016/j.jchromb.2014.03.014

Magiera, S., Pardylla, A., & Baranowska, I. (2015). Effects of various factors of ultrasonic treatment on the extraction recovery of drugs from fish tissues. Ultrasonics Sonochemistry, 26, 388-398. doi:10.1016/j.ultsonch.2015.03.005

Marchi, I., Rudaz, S., & Veuthey, J. -. (2009). Sample preparation development and matrix effects evaluation for multianalyte determination in urine. Journal of Pharmaceutical and Biomedical Analysis, 49(2), 459-467. doi:10.1016/j.jpba.2008.11.040

Musa, M., Wan Ibrahim, W. A., Mohd Marsin, F., Abdul Keyon, A. S., & Rashidi Nodeh, H. (2018). Graphene-magnetite as adsorbent for magnetic solid phase extraction of 4-hydroxybenzoic acid and 3,4-dihydroxybenzoic acid in stingless bee honey. Food Chemistry, 265, 165-172. doi:10.1016/j.foodchem.2018.04.020

Naing, N. N., Li, S. F. Y., & Lee, H. K. (2016). Evaluation of graphene-based sorbent in the determination of polar environmental contaminants in water by micro-solid phase extraction-high performance liquid chromatography. Journal of Chromatography A, 1427, 29-36. doi:10.1016/j.chroma.2015.12.012

Otoukesh, M., Es'haghi, Z., Feizy, J., & Nerin, C. (2020). Graphene oxide/ layered double hydroxides@ sulfonated polyaniline: A sorbent for ultrasonic assisted dispersive solid phase extraction of phthalates in distilled herbal beverages. Journal of Chromatography A, 1625 doi:10.1016/j.chroma.2020.461307

Partani, P., Modhave, Y., Gurule, S., Khuroo, A., & Monif, T. (2009). Simultaneous determination of propranolol and 4-hydroxy propranolol in human plasma by solid phase extraction and liquid chromatography/electrospray tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 50(5), 966-976. doi:10.1016/j.jpba.2009.06.050

Roy, K. S., Purohit, A. K., Chandra, B., Goud, D. R., Pardasani, D., & Dubey, D. K. (2018). Polymeric sorbent with controlled surface polarity: An alternate for solid-phase extraction of nerve agents and their markers from organic matrix. Analytical Chemistry, 90(11), 7025-7032. doi:10.1021/acs.analchem.8b01428

Sajid, M. (2017). Porous membrane protected micro-solid-phase extraction: A review of features, advancements and applications. Analytica Chimica Acta, 965, 36-53. doi:10.1016/j.aca.2017.02.023

Sequeiros, R. C. P., Neng, N. R., Portugal, F. C. M., Pinto, M. L., Pires, J., & Nogueira, J. M. F. (2011). Development and application of stir bar sorptive extraction with polyurethane foams for the determination of testosterone and methenolone in urine matrices. Journal of Chromatographic Science, 49(4), 297-302. doi:10.1093/chrsci/49.4.297

Shah, P. A., & Shrivastav, P. S. (2018). Ion-pair solid phase extraction for the simultaneous separation and quantitation of metformin and canagliflozin in human plasma by LC-MS/MS. Microchemical Journal, 143, 181-189. doi:10.1016/j.microc.2018.08.005

Shen, Q., Gong, L., Baibado, J. T., Dong, W., Wang, Y., Dai, Z., & Cheung, H. -. (2013). Graphene based pipette tip solid phase extraction of marine toxins in shellfish muscle followed by UPLC-MS/MS analysis. Talanta, 116, 770-775. doi:10.1016/j.talanta.2013.07.042

Tache, F., David, V., Farca, A., & Medvedovici, A. (2001). Microchem.J., 68, 398-404. Retrieved from www.scopus.com

Wabaidur, S. M., AlAmmari, A., Aqel, A., AL-Tamrah, S. A., Alothman, Z. A., & Ahmed, A. Y. B. H. (2016). Determination of free fatty acids in olive oils by UPHLC–MS. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1031, 109-115. doi:10.1016/j.jchromb.2016.07.040

Yamamoto, T., Kusama, M., Matsuno, K., Sugiyama, E., Yamada, Y., & Iga, T. (2002). A new method for determination of buformin in plasma and urine by ion-paired reversed-phase HPLC with ultraviolet detection. Biomedical Chromatography, 16(7), 453-454. doi:10.1002/bmc.182

Zakaria, M. B., Tan, H., Kim, J., Badjah, A. Y., Naushad, M., Habila, M., . . . Lin, J. (2019). Structurally controlled layered ni 3 C/graphene hybrids using cyano-bridged coordination polymers. Electrochemistry Communications, 100, 74-80. doi:10.1016/j.elecom.2019.01.004

Zhang, L., Wang, Z. -., Li, H., Liu, Y., Zhao, M., Jiang, Y., & Zhao, W. -. (2014). Simultaneous determination of 12 illicit drugs in whole blood and urine by solid phase extraction and UPLC-MS/MS. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 955-956(1), 10-19. doi:10.1016/j.jchromb.2014.02.007

Zhang, Z. L., & Zhou, J. L. (2007). Simultaneous determination of various pharmaceutical compounds in water by solid-phase extraction-liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1154(1-2), 205-213. doi:10.1016/j.chroma.2007.03.105


This material may be protected under Copyright Act which governs the making of photocopies or reproductions of copyrighted materials.
You may use the digitized material for private study, scholarship, or research.

Back to previous page

Installed and configured by Bahagian Automasi, Perpustakaan Tuanku Bainun, Universiti Pendidikan Sultan Idris
If you have enquiries, kindly contact us at pustakasys@upsi.edu.my or 016-3630263. Office hours only.