Background: Diabetes mellitus is a metabolic diseases characterized by disordered metabolism and abnormally high levels of blood glucose. Aim: This study was conducted to study the effects of Areca catechu seeds and Ficus deltoidea fruits methanolic extracts on glycemic and reproductive parameters of alloxan-induced diabetic rats. Methodology: Diabetes mellitus was induced by a single intraperitoneal injection of 100 mg/kg bwt alloxan monohydrate. Blood glucose level was estimated using electronic glucometer and sperm parameters were measured using Makler chamber. Insulin and testosterone were estimated by ELISA kits. Results: A. catechu and F. deltoidea methanolic extracts significantly reduced blood glucose levels and increased insulin secretion. Both extracts also significantly increased sperm quality and testosterone secretion in diabetic rats. Conclusion: Present study demonstrated anti-hyperglycemic and pro-fertility effects of A. catechu and F. deltoidea methanolic extracts i.....

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Introduction: Cancer is a major issue in medical science with increasing death cases every year worldwide. Therefore, searching for alternatives and nonorthodox methods of treatments with high efficiency, selectivity and less toxicity is the main goal in fighting cancer. Acetyl-11-keto-?-boswellic acid (AKBA), is a derivative pentacyclic triterpenoid that exhibited various biological activities with potential anti-tumoral agents. In this research, AKBA was utilized to examine the potential cytotoxic activity against MCF-7 cells in vitro and monitor the cellular and morphological changes with a prospective impact on apoptosis induction. Methods: The cytotoxic activity of AKBA was measured by 3(4,5dimethylthiazole- 2-yl)-2,5 diphyneltetrazolium bromide (MTT) assay. A dose-dependent inhibition in MCF-7 cell viability was detected. The clonogenicity of MCF-7 cells was significantly suppressed by AKBA increment in comparison with untreated cells. Result: Morphologically, exposure of MCF-7 c.....

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