The purpose of this study was to investigate whether the integration of Simulation in 5E teaching and learning approach is more effective than conventional teaching and learning. The study further investigate the comparisons of achievement in higher and lower of experimental group with higher and lower of control group. The quasi-experimental design 2x2  was used. This study involved 56 form four secondary school students in Chemor, Ipoh. The participants consist of two existing groups (science 1 and science 2), whereby each group has higher and lower achiever. Experimental group was exposed to Simulation in teaching and learning while control group experienced the conventional teaching and learning. The result shows that there is an increase in scores on the post test performance among students in the experimental group compare with the control group (F2-60 = 0.004, p..

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