The purpose of this study was to investigate the chemical compounds from the calyces of Hibiscus sabdariffa Linn. and their α-glucosidase inhibitory activity. Samples were collected from Balik Pulau, Pulau Pinang. The total of three kilogram of samples were air dried at room temperature, grinded and serially extracted by solid liquid extraction technique using hexane, dichloromethane, methanol, ethanol and water. Compounds were isolated and purified by several chromatographic techniques. Their structures were elucidated with spectroscopic methods including Nuclear Magnetic Resonance (1D-NMR and 2D-NMR), Liquid Chromatography-Mass (LCMS) spectrometry, infrared (IR) spectroscopy, ultraviolet (UV) spectroscopy and compared with data reported in the literature. The α-glucosidase inhibitory activity on the crude extracts and pure compounds was conducted using α -glucosidase inhibitory assay. The finding of this phytochemical study has led to the isolation of seven pure compounds namely s.....

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