This study aimed to investigate the properties of aphrodisiac and to evaluate the toxicological effect of leaves aqueous extract from Aquilaria malaccensis (AEAM) and Aquilaria subintegra (AEAS) against ICR mice. The aphrodisiac properties, which include sexual behaviour, orientation activity, number of offspring, male to female ratio of offspring, the percentage of pregnancy and testosterone level. Meanwhile, toxicological evaluation consists of acute and sub-acute study. In aphrodisiac study, the treated groups received 50, 100, 200, 500, and 1000 mg/kg body weight (b.w.) of extracts for 21 consecutive days. In acute toxicity study, the treated animals received a single dose at 2000 mg/kg b.w., while in sub-acute toxicity study, the treated groups received 50, 100, 150, 200, 500, and 1000 mg/kg b.w. of extracts for 21 consecutive days compared to control groups that received normal saline only. Statistical analyses were performed using t-test and one-way ANOVA and also co.....

2003 hits