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Total records found : 2
Simplified search suggestions : Nurunajah Ab Ghani
12022
article
Chemical constituents from diospyros argentea griff. (Ebenaceae)
Nurunajah Ab Ghani
Diospyros argentea is distributed mainly in Southeast Asia where it has been used to repel mosquitoes and its pounded roots are applied externally to treat herpes zoster. Chemical investigation of D. Argentea leaves resulted in the isolation of three steroids, β-sitosterol (1), β-sitostenone (2), and stigmasterol (3), together with five triterpenes, identified as friedelin (4), taraxerol (5), taraxerone (6), betulin (7), and lupeol (8). Their structures were elucuidated using spectroscopic analysis and chemical evidence. To the best of our knowledge, all compounds were isolated for the first time from this species...

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22023
article
Characterization of Phenolic Compounds from Pavetta graciliflora Wall. ex Ridl. (Rubiaceae) and their Lipoxygenase Inhibitory Activity
Nurunajah Ab Ghani
Pavetta genus belongs to the family Rubiaceae. The genus is used in traditional medicine to treat various diseases, including hemorrhoids, headaches, urinary conditions, ulcerated nose, and drops. The present study describes the investigation of the phytochemicals from Pavetta graciliflora and their lipoxygenase inhibitory activity. The isolation and purification of the compounds were carried out on the extracts using various chromatographic methods and identified by directly comparing their spectroscopic data with the respective published data. The isolated compounds were tested for anti-inflammatory activity by using lipoxygenase assay. Fractionation and purification of the leaves extract of P. graciliflora led to the isolation and identification of seven phenolics; (+)-catechin (1), (+)-epicatechin (2), quercetin (3), kaempferol (4), myricetin (5), apigenin (6), and luteolin (7), together with ?-sitosterol (8), ?-sitostenone (9), and lupeol (10). Isolated compounds demonstrated rema.....

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