AbstractThe aims of this study are to determine the chemical structures of the isolated compounds from the leaves and stem bark of Ficus deltoidea var. kunstleri by using various type of spectroscopy and to evaluate their antidiabetic activities. The isolation process of isolated compounds involved extraction, separation and purification by using column chromatography and preparative thin layer chromatography techniques. These compounds were structurally identified by using various spectroscopic techniques such as 1D (1H,13C and DEPT) and 2D-NMR (HMBC,HMQC and COSY), UV, IR and mass spectrometry; and also by comparison with previous studies. Study on in-vitro antidiabetic activities were evaluated by using α-glucosidase inhibitory assay with 4- nitrophenyl-α-D-glucopyranoside (pNPG) as substrate. As findings, chromatographic purification of F. deltoidea var. kunstleri afforded eleven chemical compounds: α- tocopherol, β-amyrin cinnamate, triglycerides fatty acids, hexadecyl palmitate, berg.....