The purpose of this study was to investigate the essential oils, phytochemicals, and antioxidant activity of Magnolia candollii and Magnolia alba (Magnoliaceae). The essential oils were obtained via hydrodistillation technique and their chemical compositions were determined by gas chromatography-flame ionization detection (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The phytochemicals were isolated using chromatography techniques and their structures were confirmed by spectroscopic data and comparison with literature. The antioxidant activity was determined through total phenolic content and DPPH free radical scavenging assay. The study showed that the essential oil of M. candollii consists of α-pinene (29.7%), elemol (10.2%), β-pinene (8.5%), β-caryophyllene (7.2%), α-terpineol (7.0%), and guaiol (5.4%). In addition, the major components of essential oil from M. alba were linalool (65.4%), β-caryophyllene (6.7%), and (E)-nerolidol (5.2%). Isolation and p.....

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The purposes of this study were to investigate the phytochemicals and antioxidant activity from Magnolia alba (Magnoliaceae). The antioxidant activity was investigated using total phenolic content and DPPH free radical scavenging assay. Isolation and purification of the leaf extracts of M. alba yielded six phytochemicals identified as squalene (1), parthenolide (2), vanillin (3), stigmasterol acetate (4), friedelin (5), and β-sitosterol (6). In antioxidant activity, the hexane extract of M. alba showed the highest value of phenolic content with 206.7 mg GAE/g, whereas methanol extract gave the highest inhibition in DPPH assay with 36.0%. However, all compounds were found weak activity in DPPH assay. The implication of this study demonstrates that M. alba could represent a source of molecules with antioxidant potential in the prevention of free radical-related diseases such as atherosclerosis and diabetes. Keywords: Magnoliaceae; Magnolia alba; phytochemicals; parthenolide; antioxidan.....

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