The complexity of meiosis, combined with a lack of knowledge about chromosomes and misconceptions, contributes to students' difficulty understanding this process. Therefore, this study aimed to develop a Cell-Wolf Game as a teaching tool for form four biology students learning about meiosis and to assess its usability based on teacher trainees' perceptions. This study uses a developmental research design by employing ADDIE model as the instructional design model. Two instruments were used in this study: expert validation form and the usability perception of the questionnaire. Two biology lecturers have been appointed to assess the validity of teaching aid material content and questionnaires. A total of 103 trainee teachers from the Bachelors of Education (Biology) programme were selected as respondents for the field study. The study showed the content validity index for both the teaching aid material, and the questionnaire is 1.0, meanwhile, the reliability index for questionnaire was .....

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