This study aims to investigate the potential use of biochemical seed oils of agro-waste as anti-trypanosomal, anti-oxidant, and anti-bacterial edible oil, sun-protection oil, and biodiesel. A comparative study was conducted to examine the chemical profile, physicochemical-sensory properties, and trans-esterification of seed oils collected from agro-waste in the Mualim district. Five drying techniques were tested before extracting the seed oils. Standard methods were then used to determine the chemical compounds, physicochemical-sensory properties, and bio-activity of the extracted seed oils. The analysis performed on such oils showed there were significant differences in the amount of seed oils between drying techniques, F (dfb, dfw) = 39.89, p = 0.00. Specifically, the analysis showed the microwave-drying technique produced the highest oil yield except for Carica papaya. L and Cucurbita sp, and the seed oils extracted from Mangifera indica had the best antioxidant property......

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