AbstractThe aim of this study was to determine essential oil composition, phytochemicals, and to evaluate bioactivities of Boesenbergia albosanguinea (Zingiberaceae) rhizomes. The essential oil was extracted using hydrodistillation and its chemical composition was determined via gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS). The rhizome was extracted using Soxhlet extraction (n-hexane, ethyl acetate, and methanol). Phytochemicals of each extract were isolated by chromatographic techniques and their structures were confirmed using spectroscopic analysis and comparison with literature. The antioxidant activity was determined using the 2,2- diphenylpicrylhydrazil (DPPH) free radical scavenging assay, and the antiinflammatory activity was evaluated using the lipoxygenase inhibition assay. The study indicates that the essential oil of B. albosanguinea comprised elemicin (44.0%), _- gurjunene (9.3%), _-caryophyllene (4.5%), and safrole (4.1%). Isolation and purification of.....