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Total records found : 3
Simplified search suggestions : Muhammad Hafiz Husna Hasnan
12014
Article
Hernagine type of Aporphine Alkaloids from Alseodaphne perakensis
Md Nazimuddin Mahfuzah, Husna Hasnan Muhammad Hafiz, Ahmad Kartini, Awang Khalijah, Nafiah Mohd Azlan,
A phytochemical study of the stem bark of Alseodaphne perakensis (Lauraceae) had been carried out. The dichloromethane crude extract from stem bark of Alseodaphne perakensis (Lauraceae) yielded two hernagine type of aporphine alkaloids namely oxohernagine and N-methylhernagine. The isolation and purification of these alkaloids were achieved using Column Chromatography (CC) and Preparative Thin Layer Chromatography (PTLC) techniques. The structural elucidations were performed by spectral methods notably Nuclear Magnetic Resonance (NMR) Spectroscopy one-dimentional (1H, 13C and DEPT) and two-dimentional (COSY, HMQC/HSQC and HMBC)...

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22014
Article
Isolation of aporphine alkaloid from the leaves of Alseodaphne corneri Kosterm
Khoo Jennie, Hui Chen, Ahmad Kartini, Hasnan Muhammad Hafiz Husna, Mohammad Siti Nor Fadzilah, Awang Khalijah, A. Hadi A. Hamid, Nafiah Mohd Azlan,
A phytochemical study on the leaf extract of Alseodaphne corneri Kosterm involving extraction, separation by using various chromatographic methods and structural determination by spectroscopic technique such as ultraviolet spectra (UV), infrared spectra (IR), nuclear magnetic resonance (NMR) and mass spectra (MS) was carried out. The isolation and purification from the leaves of Alseodaphne corneri Kosterm yielded two aporphines: norlirioferine and lirioferine...

5821 hits

32014
Thesis
Isolation of alkaloids from Alseodaphne pendulifolia Gamd. (Lauraceae) and their biological activities
Muhammad Hafiz Husna Hasnan
The purpose of this study is to extract, isolate and elucidate the structure of alkaloid constituents from barks of Alseodaphne pendulifolia Gamb. (Lauraceae) and to determine the biological activities (antiplasmodial, cytotoxicity, antibacterial and antioxidant) against the isolated alkaloids. The samples were collected from Sg. Temau Forest Reserve, Kuala Lipis, Pahang and Sg. Tekam Forest Reserve, Jerantut, Pahang, Malaysia. The isolation and purification of alkaloids were done using various chromatographic techniques including chromatotron, column, preparative thin-layer and thin-layer chromatography. The structure elucidations of the isolated alkaloids were established by NMR spectral data using various 1D-NMR (¹H, ¹³C, and DEPT) and 2D-NMR (COSY, HMQC/HSQC, HMBC, H2BC, HSQC-TOCSY and NOESY) techniques, aided via UV, IR, MS data and also by comparison with data from the literature.Further isolation process of the plants yielded four types of isoquinoline alkaloids: aporphine, a.....

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