Uracil derivatives have been the focus of many researchers examining their potential as a cancer-fighting agent. Human breast, liver, and lung cancer cells were used to test the target compounds and compared to cisplatin. There was a wide range of activity in the newly synthesized compounds against breast and lung cancer, but none were effective against liver cancer. Nevertheless, the most effective substances were 4d and 4j, which were quite effective against both kinds of cell lines. It was shown that the 4d compound is more effective against breast cancer than 4a, 4b, and 4c compounds, and 4j showed higher cytotoxic activity than 4e, 4f, and g compounds. We have been told that further research into the toxicity of these potent substances, as well as in-vivo testing, are necessary. 2023, Iranian Chemical Science and Technologies Association. All rights reserved...

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[No abstract available]..

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This study sought to identify the chemical composition of smoke condensate of Goniothalamus andersonii (Annonaceae) and comparatively evaluate the effectiveness of smoke condensate. The chemical composition has been determined by GC-MS. Five main components were contained in aqueous fraction, namely eugenol (25.31%), (E)-cinnamaldehyde (21.13%), hexamethylene diacrylate (7.0%), caryophyllene (6.25%), and ethyl oleate (4.3%). While, three main components were detected in the n-hexane fractions, namely guaiol (8.98%), ?-eudesmol (5.71%), and (-)-cyperene (3.06%). Laboratory research was conducted to determine the repellency of the smoke condensate of Aedes aegypti mosquitoes at two levels of concentration (5.0% and 10.0%). Tests were carried out to establish the percentage reduction of mosquito landing for each of the concentrations. The synthetic insect repellent, N, N-diethyl-m-toluamide (DEET), was used as a standard at a similar level of concentration. At 5.0% concentration, DEET pro.....

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