Biology students at universities must learn about a variety of topics related to genetics.  Non-mendelian genetics, particularly the maternal effect, is one of the topics covered in genetics.  Maternal effect explained the influence of the mother's genetics onto  the  offspring’s  phenotype.   The  purpose  of  this  study  is  to  develop MamaXGenius card games as learning aids and to  investigate the perception of biology majors students on the use of MamaXGenius for the topic  Maternal Effect in Genetic. The ADDIE model had been utilised in the development stage. This study  involved 170 biology students that took the Genetic subject for Semester 3 to 7. The instruments  used in this study are questionnaires to evaluate the validity of MamaXGenius,  assess  the   validity  of  a perception questionnaire, and gauge perceptions through a four-point Likert scale.  For the validity of the MamaXGenius card game, two experts of secondary school teachers.....

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