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45 record(s) found

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Extraction and isolation of alkaloids from the leaves of alseodaphne corneri (Lauraceae)

Abstract

This phytochemical study is aimed to extract, isolate and identify alkaloids from Alseodaphne corneri leaves. The crude alkaloid was extracted by cold percolation followed by acid-base extraction until Mayer test showed negative result. Then, it was separated by conventional chromatographic methods using column chromatography and preparative thin layer chromatography. The structural elucidation of isolated alkaloids was then carried out by spectroscopic techniques; UV, IR, NMR and HRESIMS. The structures of the compounds were also determined by comparison with previous study. Isolation of alkaloids yielded one new benzylisoquinoline; (6,7- dimethoxyisoquinolinyl)-(2',5'-dihydroxy-4'-methoxyphenyl)-methanone 68, one bisbenylisoquinoline; obamegine 49, one oxoaporphines; atheroline 71, and five aporphine; isocorydine 48, N-methyllaurotetanine 51, laurotetanine 53, lirioferine 69 and norlirioferine 70. The benzylisoquinoline type alkaloid, lirioferine 69 and atheroline 71 were first repor.....

Thesis Published 2015 3877 hits Available

A new record from East Malaysia Sphaerolaimus macrocirculus (Nematoda)

Mohd Rosli Norliana, Mohd Long Shabdin, Cheng Ann Chen,

Abstract

A new record of Sphaerolaimus macrocirculus (Filipjev 1918) in East Malaysian coastal water was described. The species was isolated from the muddy area of Muara Tebas, Sarawak, Malaysia. A total of 47 species of Sphaerolaimus have been reported worldwide. Samples of Sphaerolaimus macrocirculus were previously recorded in the sublittoral mud area of temperate country. S. macrocirculus possesses a stout body (1.1 – 1.6 mm; De Man ratios: a (body length/body width) = 16.8 – 27.5; b (body length/oesophagus length) = 2.3 – 4.3; c (body length/tail length) = 5.6 – 8.6). The circular amphid is very clear and situated at the base of the cephalic capsule. In male, the amphid ranged from 11.3 – 14.3 μm in diameter (mean = 12.7 ± 1.3) and 0.4 c.d. (corresponding diameter). In female, the amphid ranged from 7.2 – 9.4 μm in diameter (mean 7.8 ± 0.9) and 0.2 c.d. The species is characterised by the presence of eight groups of subcephalic setae at the head region and three longer term.....

Article Published 2013 3812 hits Available

Extraction and isolation of alkaloids from the leaves of Alseodaphne corneri Kosterm

Nafiah Mohd Azlan, Khoo Jennie,Hui Chen, Mohammad Siti Nor Fadzilah, Awang Khalijah, A. Hadi A. Hamid, Ahmad Kartini,

Abstract

The isolation and purification of the leaves extract of Alseodaphne corneri Kosterm yielded four alkaloids; norisocorydine 1, isocorydine 2, 2-norobamegine 3 and obamegine 4. This phytochemical study involves extraction, separation by using various chromatographic methods and structural determination by spectroscopic technique such as ultraviolet spectroscopy (UV), infrared spectroscopy (IR), nuclear magnetic resonance spectroscopy (NMR) including 1D-NMR (1H, 13C and DEPT), 2D-NMR (COSY, NOESY, HMQC/HSQC, and HMBC) and mass spectrometry (MS). The IC50 value of antiplasmodial activity for isocorydine 2 and obamegine 4 are 0.50 μmolL-1 and 0.14 μmolL-1 respectively...

Article Published 2013 6778 hits Available

Isolation of aporphine alkaloid from the leaves of Alseodaphne corneri Kosterm

Khoo Jennie, Hui Chen, Ahmad Kartini, Hasnan Muhammad Hafiz Husna, Mohammad Siti Nor Fadzilah, Awang Khalijah, A. Hadi A. Hamid, Nafiah Mohd Azlan,

Abstract

A phytochemical study on the leaf extract of Alseodaphne corneri Kosterm involving extraction, separation by using various chromatographic methods and structural determination by spectroscopic technique such as ultraviolet spectra (UV), infrared spectra (IR), nuclear magnetic resonance (NMR) and mass spectra (MS) was carried out. The isolation and purification from the leaves of Alseodaphne corneri Kosterm yielded two aporphines: norlirioferine and lirioferine...

Article Published 2014 7576 hits Available

The effects of a Chinese and Cuban music programme on the cultural understanding of elementary children

Chen-Hafteck, Lily

Abstract

This study aims to examine whether the American elementary students increase their cultural understanding after a six-week multicultural music programme on China and Cuba, considering factors of age, gender and learning needs. The use of Edwards’ (1994) levels of cultural understanding as a research tool and the way in which this approach can motivate children learning were examined. Participants were 110 second and fifth graders of two schools in New Jersey. Interviews were administered before and after the programme and classroom observations were conducted. Data indicated that such multicultural music programme has increased children’s cultural understanding and reduce their stereotypes on other people. Different levels of cultural understanding have been demonstrated. It was easy for children to achieve the basic level (i.e. Level 1: Knowledge) but it became more and more difficult as the levels proceed (i.e. Levels 2-4: Awareness, Sensitivity and Valuing). Therefore, multicult.....

Article Published 2018 1386 hits Available

Kepentingan Huiguan (persatuan Cina) terhadap orang Cina Bentong semasa zaman kolonial British

Yang, Chen

Abstract

Tujuan artikel ini bertujuan meneliti kepentingan dan peranan huiguan dalam komuniti Cina semasa pentadbiran British. Artikel ini berfokus kepada huiguan yang ditubuhkan sebelum tahun 1957 dan peranan huiguan tersebut terhadap orang Cina Bentong. Kaedah kualitatif telah digunakan dalam kajian ini. Analisis kajian ini dilakukan berdasarkan kepada sumber primer dan sekunder daripada laporan tahunan dan manuskrip persatuan, buku, jurnal, serta majalah terbitan huiguan. Hasil kajian ini menunjukkan bahawa Persatuan Dewan Perniagaan Cina Bentong, Persatuan Kwangsi Bentong dan Persatuan Dewan Perhimpunan Cina ialah huiguan yang paling awal ditubuhkan dan berpengaruh dalam komuniti Cina Bentong. Penubuhan Huiguan tersebut memainkan peranan penting dalam menyediakan kebajikan dan bantuan kepada anggota seperti menyediakan tempat penginapan sementara memberi peluang pekerjaan, menguruskan hal perkahwinan dan pengebumian ahli, mengadakan aktiviti tradisi, adat resam dan kepercayaan orang antara .....

Article Published 2018 1131 hits Available

Supervised and unsupervised learning in data mining for employment prediction of fresh graduate students

Abdul Rahman Nor Azziaty, Tan Kian Lam, Lim Chen Kim,

Article Published 2017 2023 hits Limited

Lsound: an l-system framework for score generation

Lim Chen Kim, Tan Kian Lam, Yusran Hazwanni, Suppramaniam Vicknesh,

Article Published 2017 1862 hits Limited

Proposed best practices to visualization of heritage buildings based on artistic considerations

Lim, Chen Kim

Abstract

The digital preservation of cultural heritage of 3D reconstructed objects presents a new challenge due to difficultiesassociated with this technique. The importance of 3D reconstruction especially in the context of preservation and visualization of heritage buildings as many studies have been conducted that underlined its importance. To this effect, the present study proposed a new digital preservation best practice to visualize heritage monuments and buildings based on artistic considerations for the graphic designer responsible for this task. The best practices presented in this study includes the open standards, procedures, observations as well as considerations that are needed on the objects to be regarded as acceptable for visualization purposes. The proposed best practices were pilot tested by having 33 computer graphics students apply these practices to visualize heritage buildings as assigned..

Article Published 2019 1765 hits Available

A proposed methodology of bringing past life in digital cultural heritage through crowd simulation: a case study in George Town, Malaysia

Lim, Chen Kim

Abstract

One of the heritages can be denoting to the values of human activity in the past and its cultural oral narratives. To virtualize these heritages, it means to actualize the heritage into the digital content. When attempting to understand a particular cultural heritage site, the challenge here is that the connection to the past is non-existence due to insufficient historical information of the heritage sites. On the other hand, crowd simulation has been widely applied for the purpose of construction and reconstruction of tangible and intangible digital heritage. Therefore, the main objective of this research is to bring past life into digital cultural heritage and it would need the inclusions of the visual information of the surroundings and the people in the past. This paper also investigates the phase-by-phase methodology to deal with crowd simulation of different ethnic groups with heterogeneous behaviors in digital cultural heritage. The crowd is modeled and simulated based on the cl.....

Article Published 2019 1650 hits Limited

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