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Total records found : 2
Simplified search suggestions : Nafiah Mohd Azlan Khoo Jennie Hui Chen Mohammad Siti Nor Fadzilah Awang Khalijah A Hadi A Hamid Ahmad Kartini
12013
article
Extraction and isolation of alkaloids from the leaves of Alseodaphne corneri Kosterm
Nafiah Mohd Azlan, Khoo Jennie,Hui Chen, Mohammad Siti Nor Fadzilah, Awang Khalijah, A. Hadi A. Hamid, Ahmad Kartini,
The isolation and purification of the leaves extract of Alseodaphne corneri Kosterm yielded four alkaloids; norisocorydine 1, isocorydine 2, 2-norobamegine 3 and obamegine 4. This phytochemical study involves extraction, separation by using various chromatographic methods and structural determination by spectroscopic technique such as ultraviolet spectroscopy (UV), infrared spectroscopy (IR), nuclear magnetic resonance spectroscopy (NMR) including 1D-NMR (1H, 13C and DEPT), 2D-NMR (COSY, NOESY, HMQC/HSQC, and HMBC) and mass spectrometry (MS). The IC50 value of antiplasmodial activity for isocorydine 2 and obamegine 4 are 0.50 μmolL-1 and 0.14 μmolL-1 respectively...

4911 hits

22014
article
Isolation of aporphine alkaloid from the leaves of Alseodaphne corneri Kosterm
Khoo Jennie, Hui Chen, Ahmad Kartini, Hasnan Muhammad Hafiz Husna, Mohammad Siti Nor Fadzilah, Awang Khalijah, A. Hadi A. Hamid, Nafiah Mohd Azlan,
A phytochemical study on the leaf extract of Alseodaphne corneri Kosterm involving extraction, separation by using various chromatographic methods and structural determination by spectroscopic technique such as ultraviolet spectra (UV), infrared spectra (IR), nuclear magnetic resonance (NMR) and mass spectra (MS) was carried out. The isolation and purification from the leaves of Alseodaphne corneri Kosterm yielded two aporphines: norlirioferine and lirioferine...

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