Chemical constituents and biological activities of the aerial parts of Piper erecticaule C.DC. have been studied for the first time. Fractionation and purification of the extracts afforded aristolactam AII (1), aristolactam BII (2), piperolactam A (3), piperolactam C (4),piperolactam D (5), together with terpenoids of β-sitosterol, β-sitostenone, taraxerol, and lupeol. The structures of these compounds were obtained by analysis of their spectroscopic data, as well as the comparison with that of reported data. Acetylcholinesterase inhibitory activity revealed that compounds 1 and 3 showed strong AChE inhibitory effects with the percentage inhibition of 75.8% and 74.8%, respectively..

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Kajian  ini  bertujuan  untuk  mengenalpasti  hubungan  amalan  pengajaran  guru  mengikut persepsi   pelajar  dan  sikap  pelajar  terhadap  pencapaian  Ekonomi  Asas  di antara  Sekolah Menengah  Kebangsaan (SMK) dan Sekolah Menengah Jenis Kebangsaan Cina (SMJK) di Pulau Pinang. Persampelan  kajian terdiri daripada 125 pelajar Tingkatan 5 daripada empat buah sekolah SMK dan 125 pelajar  Tingkatan 5 daripada tiga buah sekolah SMJK di Pulau Pinang.  Kajian  menggunakan  kaedah  tinjauan   dan  data  diperoleh  dengan  menggunakan soal  selidik.  Instrumen  yang  digunakan  dalam  soal   selidik  kajian  ini  mengandungi  dua bahagian  iaitu  amalan   pengajaran   guru   mengikut    persepsi   pelajar  yang  dibangunkan berdasarkan  instrumen  soal  selidik  Wan  Mohd  Rani   Abdullah,  (1989) dengan  nilai alpha Cronbach 0.875 dan sikap pelajar terhadap Ekonomi  Asas yang  dibangunkan  berdasarkan instrume.....

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Phytochemical investigation from the leaves and stem extracts of Piper maingayi Hk.F. resulted in the isolation of a new amide,N-isobutyl-15-(3??,4??-methylenedioxyphenyl)-2E,4E,12Z-pentadecatrienamide (1), together with sesamin (2), piperumbellactam A (3), cepharadione A (4), cepharadione B (5), piperolactam A (6), oleic acid (7), methyl linolenate (8), β-sitosterol (9), butyl dodecanoate (10), and isovanillic acid (11). Their structures were established by the analysis of their spectroscopic (1D and 2D NMR) and spectrometric (MS) data, as well as by comparison with those reported in the literature. Compound (1) exhibited strong inhibition against lipoxygenase (15-LOX) at IC50 42.5 μM and antibacterial activity toward Bacillus subtillis and Pseudomas aeruginosa with minimum inhibitory concentration (MIC) value of 250 μg/mL each.  ..

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This study was designed to examine the chemical composition and anticholinesterase inhibitory activity of the essential oil of Pseuduvaria macrophylla (Oliv.) Merr. (Annonaceae) from Malaysia. The essential oil was obtained by hydrodistillation and fully analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The analysis led to the identification of thirty-four chemical components that represented 87.7 ± 0.5% of the total oil. The essential oil was found to be rich in germacrene D (21.1 ± 0.4%), bicyclogermacrene (10.5 ± 0.5%), d-cadinene (5.6 ± 0.2%), a-copaene (5.1 ± 0.3%), and a-cadinol (5.0 ± 0.3%). Anticholinesterase activity was evaluated using Ellman method. The essential oil showed weak inhibitory activity against acetylcholinesterase (I%: 32.5%) and butyrylcholinesterase (I%: 35.4%) assays. Our findings demonstrate that the essential oil could be very useful for the characterization, pharmaceutical and therapeutic applications of the essent.....

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The purpose of this study is to acquire expert reviews regarding a comparison between fine motor skills traditional activities with multi-touch gestures screen design. The multi-touch gestures enables children to perform multiple finger gestures such as free rotate, pinch and spread on touch screen design. The gestures are often selected because it is similar to reallife movements. Furthermore, it can enhance the interaction between users and virtual objects. Free rotate gesture enables children to rotate the objects on screen. Pinch gesture enables children to focus on the objects on screen by moving two fingers toward each other. Spread gesture enables children to make the objects look bigger on screen by moving two fingers away from each other. As these gestures involved small muscle movements, it was believed to be related to fine motor skills development. Therefore, this study aimed to get expert reviews about the pre-school children’s fine motor skills development by comparing .....

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Chemical constituents and lipoxygenase inhibitory activity of the aerial part of Piper stylosum have been studied. Fractionation and purification of the extracts afforded five lignans, identified as yangambin (1), sesamin (2), syringaresinol (3), pinoresinol (4), and medioresinol (5), together with other constituents; 4-allyl resorcinol, β-sitosterol, β-sitostenone, taraxerol, vanilin, and vanilic acid. The structures of these compounds were established by analysis of their spectral data, as compared to that of reported compounds. The lipoxygenase inhibitory activity of the extracts and isolated lignans were also evaluated..

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Kajian ini bertujuan untuk menganalisi keberkesanan Program Outbond yang telah dijalankan oleh Program Bahasa Arab Universiti Pendidikan Sultan Idris (UPSI) di Pusat Bahasa, Universiti aL Al-Bayt Mafraq Jordan pada tarikh 8 November 2017 sehingga 8 Januari 2018. Program ini merupakan program outbond pertama dianjurkan oleh pihak program Bahasa Arab UPSI dengan melibatkan universiti awam di Jordan. Jumlah peserta yang terlibat pada peringkat awal adalah seramai 80 orang, walau bagaimanapun jumlah ini berkurangan kepada 12 orang sahaja disebabkan oleh faktor kewangan peserta. Dengan jumlah peserta yang kecil, program ini diteruskan dalam usaha untuk meningkatkan peluang pembelajaran dan memberi pendedahan kepada pelajar berkaitan dengan bahasa Arab di negara penutur. Kajian berbentuk kualitatif ini menggunakan instrument temu bual dan soal selidik untuk mendapatkan data. Selain itu, kaedah analisis teks juga dilakukan untuk menyokong data temubual dan data soal selidik yang diperolehi. A.....

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The purpose of this research is to develop a symptomatic behaviour screening tool (SymBest) for early childhood educators to identify children with symptomatic behaviours. The measuring constructs of the screening tool are the child developmental domains with developmental delays as items representing the constructs. Fuzzy Delphi analysis was conducted with 18 participants from diverse backgrounds of clinical and education to gain the expert consensus on the suitability of the constructs and items representing SymBest. The findings showed that the experts have a fair degree of agreement on the constructs and the items suggested to form SymBest. The constructs and items with accepted threshold value, percentage of group consensus and fuzzy score is then organized in sequence priority to form the screening tool.  ..

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It is a very concerning situation we are having today when seeing youngsters showing less involvement and not being helpful toward the ones in need. Having children to be exposed to storybooks is to introduce them with moral values that help in building their characters. Storybooks are developed containing pedagogies adapted from the Quran that convey the value of prosocial behaviour effectively. The pedagogies are narrative, dialogue, repetition and questioning. Typography, illustrations and simplified phrases are additional elements that are also included. This research involved 60 children aged 5 to 6 years old from selected preschools in Malaysia. 30 children are presented with the original version of the storybooks and the rest are presented with modified storybooks. Modified Prosocial Behaviour Questionnaire which consists of 15 items is required to be filled during pre and post-test. There was no significant difference on the pretest (M= 32.07, SD= 3.89) and post-test (M= 32.80,.....

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Introducing a rail transit system into an urban region is expected to increase land values, and subsequently, residential property values. Despite this general belief, little is known about the spatial distributional effects of land value uplift. Thus, the goal of this paper is to provide new insights on how proximity to light rail transit stations may affect residential property values in Greater Kuala Lumpur, Malaysia using geographically weighted regression (GWR). The results provide information on spatial variations in the effects of a light rail transit system on residential property values. This study utilises GWR to account for spatial heterogeneity and spatial dependence. The results suggest that residential property values benefit from the provision of a light rail transit system but with considerable spatial variation over a geographical area. Evidently, proximity to the nearest light rail transit station gives positive premiums of up to 8% for a majority of properties locate.....

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