In the current development era, economic globalization is changing. Many jobs today have been lost due to automation and new jobs are popping up every day as a result of technological advances. In fact, technological developments also influence the way students learn, relate and interact. Skills in STEM provide a solid foundation for individuals to succeed at the school level and beyond. The global demand for STEM qualifications and skills is currently high and is expected to continue to increase in the future. This literature review is structured to see the development of STEM learning in Indonesia over the last few years, from 2015 to 2019. The visible developments are focused on STEM learning based on variations in the subjects, media, and learning strategy used. This literature review involves 28 articles of STEM field research results at several school levels, from elementary to tertiary level. From the literature search results obtained a score of 14.28% for the application of ST.....

713 hits

Background: The anticancer effects of Phyllanthus amarus extract on various cancer cells have been investigated, however, the effects of its major constituents on HCT116 human colorectal cancer cells have not been reported. Objective: In the present study, we investigated the cytotoxic effect of 80% ethanol extract of P. amarus and its marker constituents (phyllanthin, hypophyllanthin, gallic acid, niranthin, greraniin, phyltetralin, isolintetralin, corilagin and ellagic acid) on HCT116 and their underlying mechanisms of action. Methods: Their antiproliferative and apoptotic effects on HCT 116 were performed using MTT assay and flow cytometric analysis, respectively, while caspases 3/7, 8 and 9 activities were examined using the colorimetric method. The expression of cleaved poly ADP ribose polymerase enzyme (PARP) and cytochrome c proteins was investigated by the immune-blot technique. Results and Discussion: HPLC and LC-MS/MS analyses demonstrated that the extract contained mainly li.....

952 hits

This research is to find an Augmented Reality (AR) apps that suitable use for education purpose. Today, in school, students and teachers have been introduce to Internet of Thing (IoT) in technology design subject. It has considered using technology application can motivate and increase performance and student achievement in their learning units. The expected of this research is to find a good tools that can be use both of teachers or students in learning and teaching process especially for subject of Technology and Design. The early component in this apps should be a pop out image with details of electronics components until practical exercise. At the end of the used of this application, users are expected to have clear steps in mind about basic Arduino component and installations. For evaluation phases, the apps tested and used by vocational school student in subject of Technology and Design. ? 2021 ACM...

881 hits

One of the most prevalent death causes among women worldwide is breast cancer. This study aimed to characterise and differentiate the proteomics profiles of breast cancer cell lines treated with Doxorubicin (DOX) and Doxorubicin-CaCO3-nanoparticles (DOX-Ar-CC-NPs). This study determines the therapeutic potential of doxorubicin-loaded aragonite CaCO3 nanoparticles using a Liquid Chromatography/Mass Spectrometry analysis. In total, 334 proteins were expressed in DOX-Ar-CC-NPs treated cells, while DOX treatment expressed only 54 proteins. Out of the 334 proteins expressed in DOX-CC-NPs treated cells, only 36 proteins showed changes in abundance, while in DOX treated cells, only 7 out of 54 proteins were differentially expressed. Most of the 30 identified proteins that are differentially expressed in DOX-CC-NPs treated cells are key enzymes that have an important role in the metabolism of carbohydrates as well as energy, including: pyruvate kinase, ATP synthase, enolase, glyceraldehyde-3-p.....

991 hits

In 2007, the QLASSIC was introduced to assess the quality in projects workmanship which included landscaping works and due to this, many elements of non-compliance were recorded all round. The purpose of the paper is to discuss the possibility of why non-compliance in the QLASSIC assessments continued, which had-opened up several subjects' worth re-examining. A combination of mixed qualitative and quantitative research methods were employed. Critical literature review in revisiting the landscape workmanship's quality definition and construct was conducted by using the Atlas.Ti software. Meanwhile, QLASSIC data was obtained from the onsite certified third party quality assessor over a period of nine years, which began from 2007 until 2015. The findings suggested that problems of workmanship quality in landscape architecture works are quite significant. The tip of the iceberg tends to replicate that there is absence of recognised landscape workmanship assessment standards and best practi.....

480 hits

These datasets described the data of the Motor Performance Index for 7 years old kids in Malaysia based on Malaysia's physical fitness test SEGAK. This database has been designed and created with data analysis to create the index from the factor and variable of the test and the test was conducted in the majority of the national primary school in Malaysia. Gender, state of origin, and residential location of the school were the factors used to categorize the participant of the test. The factor of age, weight, height, body mass index (BMI), power, flexibility, coordination, and speed were used for the measurement to relate with the participant's physical fitness. Kids Motor Performances Index data can be reused for talent identification in sport talent scout and to create a baseline for kid's biology growth specifically in gross motor skills and cognitive growth measurement. ? 2020 The Authors..

867 hits

This paper discusses the qualifications of operators of Malaysian childcare centers, namely TASKA and TADIKA, and the challenges faced by practitioners in the industry of early childhood education (PAKK). This research used both qualitative and quantitative methods involving interviews and a survey. The sample study comprised 727 respondents consisting of 282 operators of TASKA and 343 operators of TADIKA. The research used a set of questionnaires and interview guidelines. The findings of the quantitative method showed the operators of TASKA and TADIKA had a diverse range of professional and academic qualifications, while the findings of the qualitative method highlighted a wide spectrum of challenges faced by operators of centers involved in the early childhood education industry. Collectively, such findings suggest that running a childcare center is fraught with a myriad of challenges encompassing economic, logistical, social, educational, and financial factors, which have to be addr.....

1094 hits

Alphonsea cylindrica King belongs to the family Annonaceae, which is traditionally used to treat rheumatism, bruises, and edema. Investigation of its antibacterial properties was carried out on hexane and dichloromethane crude extracts using agar diffusion method and minimum inhibitory concentration against ESKAPE pathogens. Both extracts showed positive results in inhibiting E. faecium, S. aureus, and K. pneumoniae, while the dichloromethane extract showed further inhibition against P. aeruginosa. A morphinan alkaloid, O-methylpallidinine (1), along with a methoxybenzoic acid, isovanillic acid (2), were isolated from the dichloromethane leaf extract of the plant and elucidated via NMR spectroscopy, FTIR spectroscopy, UV-vis spectroscopy, and GC-MS, and compared with the reported data. Both compounds are reported for the first time from A. cylindrica, while O-methylpallidinine was isolated as natural product for the first time from the family Annonaceae. Both 1 and 2 showed low activit.....

1172 hits

Clean water supply has an important role among flood victims at evacuation centers during the flood. However, the water supply from various unknown and unverified sources such as hygiene status can affect the flood victims health. Therefore, the purpose of this study is to evaluate the flood water quality in the Kuala Krai flooding areas. The methodology of data collection in this study are fieldwork methods. It has been used to collect flood water samples during the northeast monsoon season in December 2016 and January 2017. A total of four flood water stations have been select based on the four flood evacuation centers based on the number of flood victims. A total of 13 water quality parameters were analyzed: pH, DO, BOD, COD, SS, NH3N, turbidity, NO3, Fe, Mg, Ca, Cu and E. coli bacteria. Flood water quality assessment in this study is based on the Malaysian National Water Quality Standards by the Malaysia Department of Environment (DOE). The results showed that flood water quality w.....

618 hits

Numerous studies have focused on making telemedicine smart through the Internet of Things (IoT) technology. These works span a wide range of research areas to enhance telemedicine architecture such as network communications, artificial intelligence methods and techniques, IoT wearable sensors and hardware devices, smartphones and cloud computing. Accordingly, several telemedicine applications covering various human diseases have presented their works from a specific perspective and resulted in confusion regarding the IoT characteristics. Although such applications are useful and necessary for improving telemedicine contexts related to monitoring, detection and diagnostics, deriving an overall picture of how IoT characteristics are currently integrated with the telemedicine architecture is difficult. Accordingly, this study complements the academic literature with a systematic review covering all main aspects of advances in IoT-based telemedicine architecture. This study also provides a.....

532 hits